6. Parkinson disease Clinical trials / Disease details


Clinical trials : 2,307 Drugs : 2,007 - (DrugBank : 349) / Drug target genes : 188 - Drug target pathways : 199

  
8 trials found
No.TrialIDDate_
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PhaseCountries
1ChiCTR2000039697
2020-11-152020-11-06Application of etomidate in deep brain stimulation under general anesthesia for Parkinson's diseaseApplication of etomidate in deep brain stimulation under general anesthesia for Parkinson's disease Parkinson DiseaseExperimental group:Etomidate-based anesthesia;Control group: Propofol-based anesthesia;Department of Anesthesiology, the First Affiliated Hospital of Sun Yat-Sen UniversityNULLRecruiting1880BothExperimental group:30;Control group:30;Phase 4China
2NCT04502550
(ClinicalTrials.gov)
October 15, 202030/7/2020Brain Networks and ConsciousnessSubcortical-cortical Network Dynamics of Anesthesia and ConsciousnessLoss of Consciousness;Parkinson Disease;Essential Tremor;AnesthesiaDrug: PropofolUniversity of Texas Southwestern Medical CenterUniversity of California, Los AngelesRecruiting18 YearsN/AAll144United States
3ChiCTR1900021760
2019-03-092019-03-08Effect-site concentration of remifentanil for I-gel insertion in male patients with Parkinson’s disease undergoing deep brain stimulator implantation during target-controlled infusion of propofolEffect-site concentration of remifentanil for I-gel insertion in male patients with Parkinson’s disease undergoing deep brain stimulator implantation during target-controlled infusion of propofol Parkinson’s diseaseParkinson’s disease:propofol and remifentanil;Non-Parkinson’s disease:propofol and remifentanil;The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of ChinaNULLRecruiting4064MaleParkinson’s disease:25;Non-Parkinson’s disease:25;N/AChina
4ChiCTR1800014542
2018-01-222018-01-20Up-down sequential testing of propofol - induced half-effective dose ( ed50 ) in patients with Parkinson's disease and non - Parkinson's diseaseUp-down sequential testing of propofol - induced half-effective dose ( ed50 ) in patients with Parkinson's disease and non - Parkinson's disease Parkinson's DiseasePD group:propofol;NPD group:propofol;Xuanwu Hospital of CCMUNULLRecruiting1865BothPD group:40;NPD group:40;China
5ChiCTR-IOR-16010168
2016-12-202016-12-15Propofol-remifetanyl vs dexmedetomidine continous infusion for deep brain stimulation implantationPropofol-remifetanyl vs dexmedetomidine continous infusion for deep brain stimulation implantation Parkinson's Diseasepropofol-remifentanyl group:propofol-remifentany infusion for monitored anesthesia care during awake deep brain stimulation surgery;dexmedetomidine group:dexmedetomidine infusion for monitored anesthesia care during awake deep brain stimulation surgery;West China Hospital, Sichuan UniversityNULLRecruiting18Bothpropofol-remifentanyl group:25;dexmedetomidine group:25;China
6NCT02256319
(ClinicalTrials.gov)
September 201430/9/2014Dexmedetomidine vs Propofol on the Recordings of Deep Brain Activity Measured Through Implanted StimulatorsEffects of Dexmedetomidine vs Propofol on the Recordings of Deep Brain Activity (Local Field Potentials) Measured Through Implanted StimulatorsParkinson's DiseaseDrug: Dexmedetomidine;Drug: PropofolClinica Universidad de Navarra, Universidad de NavarraNULLCompleted18 YearsN/ABoth12Phase 4Spain
7EUCTR2014-000868-17-ES
(EUCTR)
26/06/201417/03/2014Effect of dexmedetomidine vs propofol on basal ganglia activity (local field potentials) recorded through implanted stimulatorsEffect of dexmedetomidine vs propofol on basal ganglia activity (local field potentials) recorded through implanted stimulators Parkinson's disease
MedDRA version: 16.1;Level: LLT;Classification code 10013113;Term: Disease Parkinson's;System Organ Class: 100000004852;Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
Trade Name: Dexdor
Product Name: Dexdor
INN or Proposed INN: DEXMEDETOMIDINE
Other descriptive name: DEXMEDETOMIDINA
Trade Name: Propofol-Lipuro
Product Name: Propofol-Lipuro
INN or Proposed INN: PROPOFOL
Other descriptive name: PROPOFOL
Clínica Universidad de Navarra/Universidad de NavarraNULLNot RecruitingFemale: yes
Male: yes
Spain
8NCT00615472
(ClinicalTrials.gov)
October 20039/1/2008Intravenous Versus Inhalational Anesthesia in Parkinson's DiseaseIntravenous General Anesthesia Versus Inhalational General Anesthesia in Parkinson's DiseaseParkinson's DiseaseDrug: Isoflurane;Drug: Remifentanil;Drug: PropofolColumbia UniversityNULLTerminated18 YearsN/AAll58N/AUnited States