60. Aplastic anemia Clinical trials / Disease details
Clinical trials : 245 / Drugs : 318 - (DrugBank : 86) / Drug target genes : 44 - Drug target pathways : 166
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05720234 (ClinicalTrials.gov) | November 10, 2022 | 11/1/2023 | Avatrombopag Combined With IST as First-line Treatment for SAA | The Efficacy and Safety Study of Avatrombopag Combined With IST as First-line Treatment for Severe Aplastic Anemia, A Single-arm, Phase II Clinical Study | Severe Aplastic Anemia | Drug: avatrombopag | Institute of Hematology & Blood Diseases Hospital | NULL | Recruiting | 12 Years | 60 Years | All | 53 | Phase 2 | China |
| 2 | NCT05571332 (ClinicalTrials.gov) | June 28, 2022 | 28/8/2022 | Efficacy and Safety of Avatrombopag Combined With IST for the Treatment of HAAA and SAA With Abnormal Liver Function | Efficacy and Safety of Avatrombopag Combined With IST for the Treatment of HAAA and SAA With Abnormal Liver Function | Aplastic Anemia | Drug: Avatrombopag 20 MG Oral Tablet | Institute of Hematology & Blood Diseases Hospital | NULL | Recruiting | 18 Years | 70 Years | All | 39 | N/A | China |
| 3 | ChiCTR2200057674 | 2022-03-01 | 2022-03-15 | Clinical study of Avatrombopag combined with immunosuppressive therapy in the treatment of severe hepatitis-related aplastic anemia in children | A prospective clinical study of Avatrombopag combined with immunosuppressive therapy in the treatment of severe hepatitis-related aplastic anemia in children | Severe hepatitis-associated aplastic anaemia in children | Avatrombopag+IST: Avatrombopag; | Capital Medical University, National Center for Children’s Health | NULL | Pending | 2 | 18 | Both | Avatrombopag+IST:10; | Phase 4 | china |
| 4 | ChiCTR2100050045 | 2021-09-01 | 2021-08-16 | A Study to Assess the Safety and Efficacy of Avatrombopag in Chinese Patients with Aplastic Anemia | A Non-randomized, Open-label, Phase II Study to Assess the Safety and Efficacy of Avatrombopag in Chinese Patients With Aplastic Anemia | aplastic anemia | Group 1:Avatrombopag treatment; | Tianjin Medical University, General Hospitial | NULL | Pending | 16 | 75 | Both | Group 1:60; | Phase 4 | China |
| 5 | NCT04728789 (ClinicalTrials.gov) | February 1, 2021 | 1/12/2020 | Avatrombopag Usage in NSAA | Efficacy and Safety of Avatrombopag in Non-severe Aplastic Anemia - a Multicenter Prospective Single Arm Study | Aplastic Anemia;Drug Effect | Drug: Avatrombopag 20 MG | Peking Union Medical College Hospital | NULL | Not yet recruiting | 18 Years | 75 Years | All | 40 | Phase 2/Phase 3 | China |