65. Primary immunodeficiency Clinical trials / Disease details

Clinical trials : 500 /  Drugs : 614 - (DrugBank : 119) / Drug target genes : 92 - Drug target pathways : 217

  
5 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT05329935
(ClinicalTrials.gov)		April 202224/3/2022Congenital Athymia Patient RegistryCongenital Athymia Patient Registry of RETHYMICComplete DiGeorge Anomaly;Complete DiGeorge Syndrome;Congenital AthymiaBiological: Cultured Thymus TissueEnzyvant Therapeutics GmBHNULLRecruitingN/A21 YearsAll75United States
2NCT01220531
(ClinicalTrials.gov)		November 8, 201022/9/2010Thymus Transplantation Safety-EfficacySafety and Efficacy of Thymus Transplantation in Complete DiGeorge Anomaly, IND#9836Complete DiGeorge Anomaly;DiGeorge Syndrome;DiGeorge Anomaly;Complete DiGeorge SyndromeBiological: Cultured Thymus Tissue;Procedure: Blood Draw;Drug: Rabbit anti-thymocyte globulin;Drug: Cyclosporine;Drug: Tacrolimus;Drug: Methylprednisolone or Prednisolone;Drug: Mycophenolate mofetilM. Louise MarkertNational Institutes of Health (NIH);National Institute of Allergy and Infectious Diseases (NIAID);Enzyvant Therapeutics GmbHAvailableN/AN/AAllUnited States
3NCT00579527
(ClinicalTrials.gov)		December 19, 200520/12/2007Phase I/II Thymus Transplantation With Immunosuppression #950Phase I/II Trial of Thymus Transplantation With Immunosuppression, #950DiGeorge Anomaly;Complete DiGeorge Anomaly;Complete Atypical DiGeorge Anomaly;Complete DiGeorge Syndrome;Complete Atypical DiGeorge SyndromeBiological: Cultured Thymus Tissue for Implantation (CTTI);Other: Cultured Thymus Tissue Implantation and Parental Parathyroid Transplantation;Procedure: Blood Draw;Drug: Rabbit anti-thymocyte globulin;Drug: Cyclosporine;Drug: Tacrolimus;Drug: Methylprednisolone or Prednisolone;Drug: Daclizumab;Drug: Mycophenolate mofetilEnzyvant Therapeutics GmBHNational Institutes of Health (NIH);National Institute of Allergy and Infectious Diseases (NIAID);Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)CompletedN/AN/AAll14Phase 1/Phase 2United States
4NCT00576836
(ClinicalTrials.gov)		September 2, 200417/12/2007Thymus Transplantation Dose in DiGeorge #932Dose Study of Thymus Transplantation in DiGeorge Anomaly, IND 9836, #932.1DiGeorge Anomaly;DiGeorge Syndrome;Complete DiGeorge Anomaly;Complete DiGeorge SyndromeBiological: Cultured Thymus Tissue Implantation (CTTI);Other: Cultured Thymus Tissue Implantation with Parathyroid TransplantationEnzyvant Therapeutics GmBHNational Institutes of Health (NIH);National Institute of Allergy and Infectious Diseases (NIAID);Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)CompletedN/AN/AAll7Phase 2United States
5NCT00576407
(ClinicalTrials.gov)		October 199117/12/2007Thymus Transplantation in DiGeorge Syndrome #668Phase II Study of Thymus Transplantation in Complete DiGeorge Syndrome #668DiGeorge Syndrome;Complete Typical DiGeorge AnomalyBiological: Cultured Thymus Tissue for Implantation (CTTI)Enzyvant Therapeutics GmBHNational Institutes of Health (NIH);National Institute of Allergy and Infectious Diseases (NIAID);Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)CompletedN/AN/AAll26Phase 2United States

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