65. Primary immunodeficiency Clinical trials / Disease details

Clinical trials : 500 / Drugs : 614 - (DrugBank : 119) / Drug target genes : 92 - Drug target pathways : 217

8 trials found

diseases per page:

Showing 1 to 8 of 8 diseases

Filter by

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01659606 (ClinicalTrials.gov)	July 2012	6/8/2012	Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Con ...	Radiation- and Alkylator-free Hematopoietic Cell Transplantation for Bone Marrow Failure Due to Dysk ...	Dyskeratosis Congenita;Hoyeraal Hreidarsson Syndrome;Revesz Syndrome;Aplastic Anemia	Biological: alemtuzumab;Drug: Fludarabine;Drug: Cyclosporins;Drug: Mycophenolate mofetil;Drug: Tacrol ...	Boston Children's Hospital	Dana-Farber Cancer Institute;Children's Hospital Medical Center, Cincinnati;Children's Hospital Los ...	Active, not recruiting	30 Days	65 Years	All	40	Phase 2	United States;Norway;Sweden
2	NCT01220531 (ClinicalTrials.gov)	November 8, 2010	22/9/2010	Thymus Transplantation Safety-Efficacy	Safety and Efficacy of Thymus Transplantation in Complete DiGeorge Anomaly, IND#9836	Complete DiGeorge Anomaly;DiGeorge Syndrome;DiGeorge Anomaly;Complete DiGeorge Syndrome	Biological: Cultured Thymus Tissue;Procedure: Blood Draw;Drug: Rabbit anti-thymocyte globulin;Drug: C ...	M. Louise Markert	National Institutes of Health (NIH);National Institute of Allergy and Infectious Diseases (NIAID);En ...	Available	N/A	N/A	All			United States
3	NCT00579527 (ClinicalTrials.gov)	December 19, 2005	20/12/2007	Phase I/II Thymus Transplantation With Immunosuppression #950	Phase I/II Trial of Thymus Transplantation With Immunosuppression, #950	DiGeorge Anomaly;Complete DiGeorge Anomaly;Complete Atypical DiGeorge Anomaly;Complete DiGeorge Synd ...	Biological: Cultured Thymus Tissue for Implantation (CTTI);Other: Cultured Thymus Tissue Implantatio ...	Enzyvant Therapeutics GmBH	National Institutes of Health (NIH);National Institute of Allergy and Infectious Diseases (NIAID);Eu ...	Completed	N/A	N/A	All	14	Phase 1/Phase 2	United States
4	NCT00301834 (ClinicalTrials.gov)	January 2005	9/3/2006	Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Pati ...	Evaluation of Fludarabine, Busulfan and Alemtuzumab as a Reduced Toxicity Ablative Bone Marrow Stem ...	Congenital Amegakaryocytic Thrombocytopenia;Diamond-blackfan Anemia;Leukemia;Myelodysplastic Syndrom ...	Biological: alemtuzumab;Drug: busulfan;Drug: cyclosporine;Drug: fludarabine phosphate;Drug: methotrex ...	University of California, San Francisco	National Cancer Institute (NCI)	Completed	N/A	21 Years	All	35	Phase 2	United States
5	NCT00578643 (ClinicalTrials.gov)	March 2004	19/12/2007	Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous ...	HLA Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomat ...	Chronic Granulomatous Disease	Drug: Busulfan;Biological: Alemtuzumab;Drug: Cyclophosphamide;Drug: Fludarabine;Drug: Cyclosporine;P ...	Baylor College of Medicine	NULL	Completed	N/A	N/A	All	15	Phase 2	United States
6	NCT00006056 (ClinicalTrials.gov)	March 2000	5/7/2000	Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threate ...		Chediak-Higashi Syndrome;Graft Versus Host Disease;X-Linked Lymphoproliferative Syndrome;Familial Er ...	Drug: anti-thymocyte globulin;Drug: busulfan;Drug: cyclophosphamide;Drug: cyclosporine;Drug: etoposi ...	Fairview University Medical Center	NULL	Active, not recruiting	N/A	55 Years	Both	40	N/A	United States
7	NCT00006054 (ClinicalTrials.gov)	March 2000	5/7/2000	Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies		Immunologic Deficiency Syndromes;Chediak-Higashi Syndrome;Common Variable Immunodeficiency;Graft Ver ...	Drug: anti-thymocyte globulin;Drug: busulfan;Drug: cyclophosphamide;Drug: cyclosporine;Drug: etoposi ...	Fairview University Medical Center	NULL	Terminated	N/A	35 Years	Both		N/A	United States
8	NCT00008450 (ClinicalTrials.gov)	August 11, 1997	6/1/2001	Total-Body Irradiation Followed By Cyclosporineand Mycophenolate Mofetil in Treating Patients With S ...	Induction of Mixed Hematopoietic Chimerism in Patients With Severe Combined Immunodeficiency Disorde ...	Adenosine Deaminase Deficiency;Autosomal Recessive Disorder;Immune System Disorder;Purine-Nucleoside ...	Procedure: Allogeneic Bone Marrow Transplantation;Drug: Cyclosporine;Other: Laboratory Biomarker Ana ...	Fred Hutchinson Cancer Research Center	National Cancer Institute (NCI);National Heart, Lung, and Blood Institute (NHLBI)	Completed	N/A	N/A	All	6	Phase 1	United States

First Previous1Next Last