72. Pituitary ADH secretion disorder Clinical trials / Disease details
Clinical trials : 41 / Drugs : 27 - (DrugBank : 8) / Drug target genes : 7 - Drug target pathways : 10
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04789148 (ClinicalTrials.gov) | June 2023 | 5/3/2021 | Effects of Intranasal Oxytocin in Patients With Central Diabetes Insipidus | Effects of Intranasal Oxytocin in Patients With Central Diabetes Insipidus - A Pilot Study | Central Diabetes Insipidus | Drug: Oxytocin nasal spray | Elizabeth Austen Lawson | NULL | Not yet recruiting | 18 Years | 60 Years | All | 30 | Phase 1 | United States |
| 2 | NCT05319301 (ClinicalTrials.gov) | April 1, 2022 | 17/3/2022 | Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study) | Identification and Clinical Relevance of an Oxytocin Deficient State Following Melatonin Administration in Patients With Hypopituitarism: a Proof-of-concept, Physiopathological Study With a Control Group | Oxytocin Deficiency;Hypopituitarism;Hypothalamic Obesity;Pituitary Dysfunction;Central Diabetes Insipidus;Social Isolation | Dietary Supplement: Melatonin | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | NULL | Not yet recruiting | 18 Years | N/A | All | 40 | N/A | Spain |
| 3 | NCT04897802 (ClinicalTrials.gov) | September 13, 2021 | 17/5/2021 | Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study) | Identification and Clinical Relevance of an Oxytocin Deficient State: a Randomized, Crossover, Placebo-controlled, Proof-of-concept, Physiopathological Study (GLP1 Study) | Hypopituitarism;Central Diabetes Insipidus;Panhypopituitarism;Psychological Disorder;Social Isolation;Hypothalamic Diseases;Pituitary Diseases;Oxytocin Deficiency | Drug: Experimental: GLP1-RA (exenatide) administration;Drug: Control: Placebo administration | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Instituto de Salud Carlos III | Recruiting | 18 Years | 65 Years | All | 52 | Phase 4 | Spain |
| 4 | NCT04902235 (ClinicalTrials.gov) | July 6, 2021 | 17/5/2021 | Identification and Clinical Relevance of an Oxytocin Deficient State (CRH Study) | Identification and Clinical Relevance of an Oxytocin Deficient State: a Randomized, Crossover, Placebo-controlled, Proof-of-concept Physiopathological Study (CRH Study) | Hypopituitarism;Central Diabetes Insipidus;Panhypopituitarism;Psychological Disorder;Social Isolation;Hypothalamic Diseases;Pituitary Diseases;Oxytocin Deficiency | Drug: Experimental: CRH administration;Drug: Control: Placebo administration | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Instituto de Salud Carlos III | Recruiting | 18 Years | 65 Years | All | 52 | Phase 4 | Spain |