96. Crohn disease Clinical trials / Disease details

Clinical trials : 2,442 / Drugs : 1,278 - (DrugBank : 248) / Drug target genes : 142 - Drug target pathways : 209

20 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04991324 (ClinicalTrials.gov)	September 21, 2022	27/7/2021	Cholecalciferol Comedication in IBD - the 5C-study	Cholecalciferol Comedication in Patients With Chronic Inflammatory Bowel Diseases (Crohn's Disease or Ulcerative Colitis) - the 5C-study	Inflammatory Bowel Diseases	Drug: Vitamin D3	University Hospital, Basel, Switzerland	NULL	Recruiting	18 Years	N/A	All	150	Phase 3	Switzerland
2	NCT05624801 (ClinicalTrials.gov)	September 1, 2022	14/11/2022	Cholecalciferol in Chronic Inflammatory Bowel Diseases	Cholecalciferol Comedication in Patients With Chronic Inflammatory Bowel Diseases (Crohn's Disease or Ulcerative Colitis) - the 5C-study	IBD	Drug: D3 VitaCaps®	University Hospital, Basel, Switzerland	NULL	Recruiting	18 Years	N/A	All	150	Phase 3	Switzerland
3	NCT04225819 (ClinicalTrials.gov)	October 1, 2020	3/1/2020	Adjunctive Treatment With Vitamin D3 in Patients With Active IBD	Adjunctive Treatment With Vitamin D3 in Patients With Active IBD (ACTIVATED): A Randomized, Double-blind, Placebo-controlled Trial	IBD;Inflammatory Bowel Diseases;Crohn Disease;Ulcerative Colitis;Vitamin D3 Deficiency	Dietary Supplement: Vitamin D3;Other: Placebo	Massachusetts General Hospital	NULL	Recruiting	18 Years	N/A	All	100	N/A	United States
4	NCT03999580 (ClinicalTrials.gov)	February 7, 2020	24/6/2019	The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )	A Pragmatic Randomized Controlled Trial on High Dose Vitamin D to Prevent Relapses of Crohn's Disease in Children	Crohn Disease	Drug: vitamin D3	Jantchou Prevost	NULL	Recruiting	4 Years	18 Years	All	316	Phase 3	Canada
5	NCT03718182 (ClinicalTrials.gov)	September 17, 2019	23/10/2018	Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy?	Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy? D-CODE Feasibility Randomised Controlled Trial	Crohn Disease;Vitamin D Deficiency	Dietary Supplement: Cholecalciferol	University Hospital Birmingham NHS Foundation Trust	National Institute for Health Research, United Kingdom;University of Birmingham;Clinical Trials Research Centre	Recruiting	18 Years	N/A	All	50	Phase 4	United Kingdom
6	NCT02186275 (ClinicalTrials.gov)	February 2016	4/7/2014	The Vitamin D in Pediatric Crohn's Disease	Randomized Controlled Trial of High Dose Vitamin D in Children With Newly Diagnosed Crohn's Disease for the Prevention of Relapses	Crohn's Disease	Drug: Vitamin D3 : 3000 or 4000 UI/day then 2,000 UI/day;Drug: Vitamin D3 800 UI/day then 800 UI/day	St. Justine's Hospital	Canadian Institutes of Health Research (CIHR)	Completed	9 Years	18 Years	All	25	Phase 3	Canada
7	NCT02208310 (ClinicalTrials.gov)	April 2015	1/8/2014	Trial of High Dose Vitamin D in Patient's With Crohn's Disease	A Randomized Controlled Trial of High-Dose Vitamin D in Crohn's Disease	Crohn's Disease;Vitamin D Deficiency	Drug: Cholecalciferol 10,000 IU;Drug: Cholecalciferol 400 IU	University of Michigan	Crohn's and Colitis Foundation	Terminated	18 Years	75 Years	All	11	Phase 4	United States
8	EUCTR2013-002838-20-BE (EUCTR)	09/12/2014	15/09/2014	The effect of Vitamin D to prevent post-operative relapse of Crohn's Disease	The effect of Vitamin D3 to prevent post-operative relapse of Crohn’s Disease: a placebo-controlled randomized trial (DETECT) - DETECT	Crohn's Disease MedDRA version: 19.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Trade Name: D-CURA Product Name: D-Cura INN or Proposed INN: Cholecalciferol Other descriptive name: CHOLECALCIFEROL CONCENTRATE (WATER-DISPERSIBLE FORM)	Academic Medical Center	NULL	Not Recruiting			Female: yes Male: yes	142	Phase 3	Belgium;Netherlands
9	NCT04606017 (ClinicalTrials.gov)	January 1, 2014	25/10/2020	Effect of Vitamin D Supplementation on Infliximab Response in Patients With Crohn's Disease	Influence of Vitamin D3 Supplementation on Infliximab Efficacy in Chinese Patients With Crohn's Disease: A Retrospective Cohort Study	Crohn Disease;Vitamin D Deficiency;Vitamin D Supplement	Drug: Caltrate Pill	Second Affiliated Hospital of Wenzhou Medical University	NULL	Completed	18 Years	N/A	All	70		China
10	NCT02615288 (ClinicalTrials.gov)	January 2014	23/11/2015	High Dose Vitamin D3 in Crohn's Disease	Impact of High Dose Vitamin D3 Supplementation in Treatment of Crohn's Disease in Remission: A Randomized Double-blind Controlled Study	Crohn's Disease	Dietary Supplement: Vitamin D3	McMaster University	Canadian Association of Gastroenterology	Completed	18 Years	70 Years	Both	40	N/A	NULL
11	EUCTR2013-002838-20-NL (EUCTR)	12/11/2013	06/09/2013	The effect of Vitamin D to prevent post-operative relapse of Crohn's Disease	The effect of Vitamin D3 to prevent post-operative relapse of Crohn’s Disease: a placebo-controlled randomized trial (DETECT) - DETECT	Crohn's Disease MedDRA version: 18.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Trade Name: InVita D3 INN or Proposed INN: Colecalciferol Other descriptive name: CHOLECALCIFEROL CONCENTRATE	Academic Medical Center	NULL	Not Recruiting			Female: yes Male: yes	142	Phase 3	Belgium;Netherlands
12	EUCTR2013-000971-34-DK (EUCTR)	01/08/2013	01/08/2013	High dose vitamin D treatment in Crohn's disease affects the gut immune cells	Mucosal immune regulation by high dose vitamin D treatment in Crohn’s disease - MirViDiC	Active Crohn's Disease in colon and/or terminal ileum MedDRA version: 19.0;Level: LLT;Classification code 10011408;Term: Crohns disease aggravated;System Organ Class: 100000004856 ;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Trade Name: Dekristol 20.000 ie INN or Proposed INN: cholecalciferol Other descriptive name: CHOLECALCIFEROL Trade Name: Remicade INN or Proposed INN: INFLIXIMAB Trade Name: Remsima INN or Proposed INN: INFLIXIMAB	Jørgen Agnholt	NULL	Not Recruiting			Female: yes Male: yes	50	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (Phase 3): yes Therapeutic use (Phase 4): no	Denmark
13	NCT01864616 (ClinicalTrials.gov)	July 2013	22/5/2013	The Impact of Vitamin D on Disease Activity in Crohn's Disease		Crohn Disease	Dietary Supplement: Vitamin D3	University of Saskatchewan	Dania Alrefai;Dr.Jennifer Jones;Dr.Hani Jawa;Dr.Wael El-matary;Saudi Arabian Cultural Bureau	Terminated	16 Years	70 Years	All	9	N/A	Canada;Saudi Arabia
14	NCT02010762 (ClinicalTrials.gov)	February 2013	10/12/2013	The Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's Disease	The Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's Disease: a Placebo-controlled Randomized Trial	Crohn's Disease	Drug: Vitamin D;Drug: Placebo	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	NULL	Completed	18 Years	N/A	All	142	Phase 4	Netherlands
15	NCT01692808 (ClinicalTrials.gov)	October 2012	17/9/2012	Bioavailability of Vitamin D in Children and Adolescents With Crohn's Disease	Bioavailability of Vitamin D in Children and Adolescents With Crohn's Disease.	Crohn's Disease	Drug: Vitamin D3 3000 UI daily;Drug: Vitamin D3 4000 UI daily	St. Justine's Hospital	NULL	Completed	10 Years	18 Years	Both	20	Phase 2	Canada
16	NCT01369667 (ClinicalTrials.gov)	April 2012	7/6/2011	Vitamin D Supplementation in Adult Crohn's Disease	Vitamin D and Immunomodulation: Effects in Crohn's Disease	Crohn's Disease	Dietary Supplement: Vitamin D3;Other: Placebo	University of Dublin, Trinity College	Queen Mary University of London	Completed	18 Years	75 Years	Both	117	Phase 4	Ireland
17	NCT01877577 (ClinicalTrials.gov)	April 2012	11/6/2013	Supplementation of Vitamin D3 in Patients With Inflammatory Bowel Diseases and Hypovitaminosis D	Supplementation of Vitamin D3 (Cholecalciferol) in Patients With Inflammatory Bowel Diseases (IBD) and Hypovitaminosis D: A Prospective Randomized Controlled Trial.	Crohn's Disease (CD);Ulcerative Colitis (UC)	Dietary Supplement: Vitamin D3	University of California, San Francisco	NULL	Completed	18 Years	N/A	Both	30	N/A	United States
18	NCT01046773 (ClinicalTrials.gov)	January 2010	11/1/2010	Vitamin D Supplementation as Non-toxic Immunomodulation in Children With Crohn's Disease	Vitamin D Supplementation as Non-toxic Immunomodulation in Children With Crohn's Disease	Crohn's Disease;Vitamin D Deficiency	Drug: Cholecalciferol	University of California, Los Angeles	The Broad Foundation	Terminated	8 Years	18 Years	All	3	Phase 1	United States
19	NCT00672763 (ClinicalTrials.gov)	May 2008	2/5/2008	Adjuvant Vitamin D With Corticosteroids in Active Crohn's Disease	The Immunomodulatory Role of Vitamin D in Inflammatory Bowel Disease (The IBDVit Study): Double-Blind, Placebo-Controlled Trial of Adjuvant Vitamin D (Colecalciferol) With Corticosteroids in Active Crohn's Disease	Crohn's Disease	Drug: Colecalciferol D3 (Vigantol Oil);Drug: Medium chain triglycerides	Imperial College London	NULL	Withdrawn	18 Years	N/A	Both	0	Phase 4	United Kingdom
20	NCT00621257 (ClinicalTrials.gov)	January 2008	11/2/2008	Vitamin D Levels in Children With IBD	Optimization of Vitamin D Stores and Its Impact on the Bone Health and Disease Outcomes of Children and Adolescents With IBD.	Inflammatory Bowel Disease;Crohn's Disease;Ulcerative Colitis	Dietary Supplement: ergocalciferol;Dietary Supplement: Cholecalciferol	Boston Children’s Hospital	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);Crohn's and Colitis Foundation;NASPGHAN Foundation	Terminated	5 Years	21 Years	All	134	N/A	United States