96. Crohn disease Clinical trials / Disease details
Clinical trials : 2,442 / Drugs : 1,278 - (DrugBank : 248) / Drug target genes : 142 - Drug target pathways : 209
Showing 1 to 10 of 59 diseases
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05521672 (ClinicalTrials.gov) | October 24, 2022 | 22/8/2022 | Clinical Trial to Evaluate if the Laparoscopic Administration of Cells Derived From the Fatty Tissue Can Improve the Inflammatory Stenosis in Patient With Crohn's Disease Clinical Trial to Evaluate if the Laparoscopic Administration of Cells Derived From the Fatty Tissue ... | Clinical Trial Phase IIa to Evaluate the Safety and Effectiveness of Treatment With Fat-derived Mesenchymal Allogenic Mesenchymal Troncal Cells in Patients With Single Inflammatory Stenosis in the Context of Crohn's Disease. Clinical Trial Phase IIa to Evaluate the Safety and Effectiveness of Treatment With Fat-derived Mese ... | Stenosis; Bowel;Crohn Disease | Drug: Adipose derived allogenic mesenchymal stem cells (adAMSC) | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | Effice Servicios Para la Investigacion S.L. | Recruiting | 18 Years | 75 Years | All | 20 | Phase 1/Phase 2 | Spain |
| 2 | NCT05407766 (ClinicalTrials.gov) | August 2022 | 9/5/2022 | Mesenchymal Stem Cells (MSCs) for Perianal Fistula | A Phase I Safety Study of Allogeneic Bone Marrow Derived MSCs for Refractory Perianal Fistulizing Crohn's Disease A Phase I Safety Study of Allogeneic Bone Marrow Derived MSCs for Refractory Perianal Fistulizing Cr ... | Rectal Fistula | Biological: OSSM-001;Other: Placebo | Ossium Health, Inc. | NULL | Withdrawn | 18 Years | 75 Years | All | 0 | Phase 1 | NULL |
| 3 | EUCTR2021-006068-26-ES (EUCTR) | 27/07/2022 | 24/03/2022 | Clinical trial to evaluate if the laparoscopic administration of cells derived from the fatty tissue can improve the inflammatory stenosis in patient with Crohn's disease. Clinical trial to evaluate if the laparoscopic administration of cells derived from the fatty tissue ... | CLINICAL TRIAL PHASE IIa TO EVALUATE THE SAFETY AND EFFECTIVENESS OF TREATMENT WITH FAT-DERIVED MESENCHYMAL ALLOGENIC MESENCHYMAL TRONCAL CELLS IN PATIENTS WITH SINGLE INFLAMMATORY STENOSIS IN THE CONTEXT OF CROHN'S DISEASE. CLINICAL TRIAL PHASE IIa TO EVALUATE THE SAFETY AND EFFECTIVENESS OF TREATMENT WITH FAT-DERIVED MESE ... | Inflammatory stenosis in patient with Crohn's disease.;Therapeutic area: Diseases [C] - Digestive System Diseases [C06] Inflammatory stenosis in patient with Crohn's disease.;Therapeutic area: Diseases [C] - Digestive Sy ... | Product Name: allogenic mesenchymal stem cell isolated from adipose tissue INN or Proposed INN: ALLOGENEIC ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS EXPANDED Other descriptive name: ALLOGENEIC ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS EXPANDED Product Name: allogenic mesenchymal stem cell isolated from adipose tissue INN or Proposed INN: ALLOG ... | FUNDACION JIMENEZ DIAZ HEALTH RESEARCH INSTITUTE | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 20 | Phase 2 | Spain | ||
| 4 | NCT05578508 (ClinicalTrials.gov) | April 2022 | 1/11/2019 | Stem Cells for the Treatment of Pouchitis | A Phase I Study of Bone Marrow Derived Mesenchymal Stem Cells (MSCs) for the Treatment of Medically Refractory Pouchitis A Phase I Study of Bone Marrow Derived Mesenchymal Stem Cells(MSCs) for the Treatment of Medically R ... | Pouchitis;Crohn's Disease;Ulcerative Colitis Chronic;Inflammatory Bowel Diseases;Pouch, Ileal | Drug: Mesenchymal Stem Cells (MSCs) | The Cleveland Clinic | Case Western Reserve University | Withdrawn | 18 Years | 75 Years | All | 0 | Phase 1 | United States |
| 5 | NCT05262829 (ClinicalTrials.gov) | February 28, 2022 | 8/2/2022 | Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Moderate and Severe Crohn's Disease Clinical Study of Human Umbilical Cord Mesenchymal Stem Cellsin the Treatment of Moderate and Severe ... | A Single-arm, Open-label Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Refractory Moderate to Severe Crohn's Disease A Single-arm, Open-label Clinical Study of Human Umbilical Cord Mesenchymal Stem Cellsin the Treatme ... | Crohn Disease | Biological: Human Umbilical Cord Mesenchymal Stem Cells | Shanghai East Hospital | NULL | Recruiting | 18 Years | 70 Years | All | 40 | N/A | China |
| 6 | NCT05075811 (ClinicalTrials.gov) | February 1, 2022 | 28/9/2021 | Study of Ossium Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in the Setting of Crohn's Disease Study of Ossium Mesenchymal Stem Cellsfor the Treatment of Pouch Fistulas in the Setting of Crohn's ... | A Phase IB/IIA Study of Ossium Vertebral Bone Marrow Derived Mesenchymal Stem Cells (vBM-MSC) for the Treatment of Ileal Anal Anastomosis and Ileal Pouch Fistulas in the Setting of Crohn's Disease of the Pouch A Phase IB/IIA Study of Ossium Vertebral Bone Marrow Derived Mesenchymal Stem Cells(vBM-MSC) for the ... | Pouch, Ileal;Fistula | Drug: Ossium vBM-MSC;Other: Placebo | Amy Lightner | Ossium Health, Inc. | Recruiting | 18 Years | 75 Years | All | 20 | Phase 1/Phase 2 | United States |
| 7 | NCT05039411 (ClinicalTrials.gov) | January 1, 2022 | 1/9/2021 | Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) to Treat Perianal Fistulas Patients With Crohn's Disease Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells(UC-MSCs) to Treat Perianal Fistulas ... | A Phase I Study of the Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) for Perianal Fistulas in Patients With Crohn's Disease A Phase I Study of the Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells(UC-MSCs) for ... | Perianal Fistula Due to Crohn's Disease;Fistula in Ano | Biological: Human umbilical cord mesenchymal stem cells (UC-MSCs) | CryoCord Sdn Bhd | University of Malaya | Not yet recruiting | 18 Years | N/A | All | 7 | Phase 1 | Malaysia |
| 8 | NCT04073472 (ClinicalTrials.gov) | June 1, 2021 | 23/8/2019 | Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in Crohn's | A Phase I Study of Allogeneic Bone Marrow Derived Mesenchymal Stem Cells for the Treatment of Ileal Anal Anastomosis and Ileal Pouch Fistulas in the Setting of Crohn's Disease of the Pouch A Phase I Study of Allogeneic Bone Marrow Derived Mesenchymal Stem Cellsfor the Treatment of Ileal A ... | Crohn's Disease;Fistula;Anal Fistula;Pouch, Ileal;Pouches, Ileoanal | Drug: mesenchymal stem cells (MSCs) | The Cleveland Clinic | NULL | Withdrawn | 18 Years | 75 Years | All | 0 | Phase 1 | United States |
| 9 | EUCTR2017-000725-12-DK (EUCTR) | 07/04/2021 | 14/10/2020 | A clinical research study of an investigational new drug to treat perianal fistulas in patients with Crohn’s disease (CD). A clinical research study of an investigational new drug to treat perianal fistulas in patients with ... | A phase III, randomized, double blind, parallel group, placebo controlled, international, multicentre study to assess efficacy and safety of Cx601, adult allogeneic expanded adipose-derived stem cells (eASC), for the treatment of complex perianal fistula(s) in patients with Crohn’s disease over a period of 24 weeks and a follow-up period up to 52 weeks. ADMIRE-CD II study. A phase III, randomized, double blind, parallel group, placebo controlled, international, multicentr ... | Perianal fistulising Crohn´s disease MedDRA version: 20.0;Level: PT;Classification code 10002156;Term: Anal fistula;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06] Perianal fistulising Crohn´s disease MedDRA version: 20.0;Level: PT;Classification code 10002156;Ter ... | Trade Name: Alofisel Product Name: Allogenic eASCs 5 million cells/ml suspension for injection CX601 Product Code: Cx601 INN or Proposed INN: Darvadstrocel Other descriptive name: Expanded human allogenic mesenchymal adult stem cells extracted from adipose tissue (eASCs) Trade Name: Alofisel Product Name: Allogenic eASCs 5 million cells/ml suspension for injection CX601 P ... | TiGenix, S.A.U. | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 554 | Phase 3 | United States;Czechia;Spain;Israel;Italy;United Kingdom;France;Hungary;Czech Republic;Canada;Belgium;Poland;Denmark;Germany;Sweden United States;Czechia;Spain;Israel;Italy;United Kingdom;France;Hungary;Czech Republic;Canada;Belgium ... | ||
| 10 | NCT04791878 (ClinicalTrials.gov) | April 1, 2021 | 6/3/2021 | Study of Mesenchymal Stem Cells for Pediatric Perianal Fistulizing Crohn's Disease | A Phase I Study of Adult Allogeneic Bone Marrow Derived Mesenchymal Stem Cells for Pediatric Perianal Fistulizing Crohn's Disease A Phase I Study of Adult Allogeneic Bone Marrow Derived Mesenchymal Stem Cellsfor Pediatric Perianal ... | Perianal Fistula Due to Crohn's Disease (Disorder) | Drug: Mesenchymal stem cells | Amy Lightner | NULL | Recruiting | 13 Years | 17 Years | All | 10 | Phase 1 | United States |