AGT-181 ( DrugBank: - )


1 disease
IDDisease name (Link within this page)Number of trials
19Lysosomal storage disease4

19. Lysosomal storage disease


Clinical trials : 899 Drugs : 684 - (DrugBank : 99) / Drug target genes : 51 - Drug target pathways : 182
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03071341
(ClinicalTrials.gov)
October 201627/2/2017Extension Study Evaluating Long Term Safety and Activity of AGT-181 in Children With MPS IAn Extension Study Evaluating Long Term Safety and Activity of AGT-181 in Patients With Mucopolysaccharidosis I Who Were Previously Enrolled in Studies With AGT-181Mucopolysaccharidosis IDrug: AGT-181ArmaGen, IncNULLCompleted2 YearsN/AAll19Phase 1/Phase 2Brazil
2NCT02597114
(ClinicalTrials.gov)
November 20153/11/2015Extension Study of AGT-181-102 to Evaluate Long Term Safety and Activity of AGT-181An Extension Study of AGT-181-102 Evaluating Safety and Glycosaminoglycans (GAGs) in Adult Patients With Hurler-Scheie or Scheie Syndrome Who Have Completed 8-Weeks of Dosing With AGT-181 in Study AGT-181-102Mucopolysaccharidosis IDrug: AGT-181ArmaGen, IncNULLCompleted18 YearsN/AAll3Phase 1NULL
3NCT03053089
(ClinicalTrials.gov)
October 20159/2/2017Safety and Dose Ranging Study of Human Insulin Receptor MAb-IDUA Fusion Protein in Adults and Children With MPS IA Two-Stage, Phase 1/2, Open-Label Study of the Human Insulin Receptor Monoclonal Antibody-Human Alpha-L-iduronidase (HIRMAb-IDUA) Fusion Protein, AGT-181 in Patients With Mucopolysaccharidosis I (MPS I, Hurler Syndrome)Mucopolysaccharidosis IDrug: AGT-181ArmaGen, IncNULLCompleted2 YearsN/AAll21Phase 1/Phase 2Brazil
4NCT02371226
(ClinicalTrials.gov)
July 201519/2/2015Safety and Dose Ranging Study of Insulin Receptor MAb-IDUA Fusion Protein in Patients With MPS IA Phase 1 Safety and Dose-Finding Study of a Human Insulin Receptor Monoclonal Antibody-Human Alpha-L-iduronidase (HIRMAb-IDUA) Fusion Protein, AGT-181 in Adult Patients With Mucopolysaccharidosis I (MPS I, Hurler Syndrome)Mucopolysaccharidosis IDrug: AGT-181 (HIRMAb-IDUA)ArmaGen, IncNULLCompleted18 YearsN/AAll3Phase 1United States