Autologous Umbilical Cord Blood ( DrugBank: - )
2 diseases
| ID | Disease name (Link within this page) | Number of trials |
|---|---|---|
| 211 | Hypoplastic left heart syndrome | 3 |
| 294 | Congenital diaphragmatic hernia | 1 |
211. Hypoplastic left heart syndrome
Clinical trials : 22 / Drugs : 29 - (DrugBank : 9) / Drug target genes : 5 - Drug target pathways : 14
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03779711 (ClinicalTrials.gov) | June 6, 2019 | 4/12/2018 | Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome | Phase IIb Study of Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Stage II Surgical Repair of Right Ventricular Dependent Variants of Hypoplastic Left Heart Syndrome (AutoCell-S2) | Hypoplastic Left Heart Syndrome | Biological: Autologous (self) mononuclear cells derived from umbilical cord blood;Procedure: Stage II Surgical repair | Timothy J Nelson, MD, PhD | University of Oklahoma;Children's Hospital of Philadelphia;Children's Hospital Los Angeles;Children's Hospital Colorado;Children's Hospitals and Clinics of Minnesota;Ochsner Health System;Children's of Alabama;Children's Hospital Medical Center, Cincinnati | Active, not recruiting | N/A | 12 Months | All | 95 | Phase 2 | United States |
| 2 | NCT01883076 (ClinicalTrials.gov) | May 15, 2013 | 11/6/2013 | Safety Study of Autologous Umbilical Cord Blood Cells for Treatment of Hypoplastic Left Heart Syndrome | Phase I Safety Study of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Stage II Palliation of Hypoplastic Left Heart Syndrome | Hypoplastic Left Heart Syndrome | Biological: autologous cell-based delivery | Timothy J Nelson, MD, PhD | University of Oklahoma;Children's Hospital of Philadelphia;Children's Hospitals and Clinics of Minnesota;Children's Hospital Los Angeles;Children's Hospital Colorado;Mayo Clinic | Completed | N/A | 18 Months | All | 30 | Phase 1 | United States |
| 3 | NCT01445041 (ClinicalTrials.gov) | September 1, 2011 | 15/9/2011 | Safety and Feasibility Study of Umbilical Cord Blood Cells for Infants With Hypoplastic Left Heart Syndrome | Autologous Cord Blood Cells for Patients With HLHS: Phase I Study of Feasibility and Safety | Hypoplastic Left Heart Syndrome | Biological: Autologous Umbilical Cord Blood | Michael Cotten | NULL | Terminated | N/A | 2 Days | All | 7 | Phase 1 | United States |
294. Congenital diaphragmatic hernia
Clinical trials : 16 / Drugs : 26 - (DrugBank : 5) / Drug target genes : 5 - Drug target pathways : 14
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03526588 (ClinicalTrials.gov) | August 1, 2018 | 27/4/2018 | Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH) | Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH) | Congenital Diaphragmatic Hernia | Biological: Autologous umbilical cord blood | The University of Texas Health Science Center, Houston | Texas Medical Center Regenerative Medicine Consortium | Recruiting | N/A | 7 Days | All | 20 | Phase 1 | United States |