Enteral nutrition ( DrugBank: - )
1 disease
| ID | Disease name (Link within this page) | Number of trials |
|---|---|---|
| 96 | Crohn disease | 22 |
96. Crohn disease
Clinical trials : 2,442 / Drugs : 1,278 - (DrugBank : 248) / Drug target genes : 142 - Drug target pathways : 209
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05606419 (ClinicalTrials.gov) | January 2023 | 24/10/2022 | The Crohn's Disease Exclusion Diet With Early Dairy Introduction Plus Partial Enteral Nutrition for Crohn's Disease | The Crohn's Disease Exclusion Diet With Early Dairy Introduction Plus Partial Enteral Nutrition (CD-EDEN) in Adult Patients With Crohn's Disease | Crohn Disease | Dietary Supplement: CDED+PEN+dairy products;Dietary Supplement: PEN+usual care | Evangelismos Hospital | Agricultural University of Athens | Not yet recruiting | 18 Years | N/A | All | 120 | N/A | NULL |
| 2 | ChiCTR2200058343 | 2022-04-13 | 2022-04-07 | To investigate the effect of pancreatin on diarrhea of crohn's disease patients taking total enteral nutrition | To investigate the effect of pancreatin on diarrhea of crohn's disease patients taking total enteral nutrition | Crohn's disease | Experimental group:Take trypsin medications; | Renmin Hospital of Wuhan University | NULL | Pending | 18 | 75 | Both | Experimental group:53; | Phase 4 | China |
| 3 | ChiCTR2200058055 | 2022-04-01 | 2022-03-27 | A prospective, multicenter observational study of adalimumab biological analogues combined with partial enteral nutrition in the evaluation of the efficacy of Crohn's disease | A prospective, multicenter observational study of adalimumab biological analogues combined with partial enteral nutrition in the evaluation of the efficacy of Crohn's disease | Inflammatory bowel disease (IBD) | Hemienteral nutrition group:adalimumab biological analogues combined with partial enteral nutrition therapy;Internal nutrition group:adalimumab combined with total enteral nutrition;The adamumab group:adalimumab; | The First Affiliated Hospital of Shantou University Medical College | NULL | Pending | 18 | 75 | Both | Hemienteral nutrition group:30;Internal nutrition group:30;The adamumab group:60; | N/A | China |
| 4 | NCT04859088 (ClinicalTrials.gov) | September 20, 2021 | 15/4/2021 | Biologics and Partial Enteral Nutrition Study | Combining Partial Enteral Nutrition With Biologics to Optimise Induction and Maintenance Therapy for Adults With Active Ileocolonic Crohn's Disease | Crohn Disease | Dietary Supplement: Partial Enteral Nutrition | NHS Greater Glasgow and Clyde | University of Glasgow | Recruiting | 16 Years | N/A | All | 80 | N/A | United Kingdom |
| 5 | NCT04921033 (ClinicalTrials.gov) | March 1, 2021 | 4/6/2021 | Exclusive Enteral Nutrition in Patients With Ileocaecal Crohn's Disease | Exclusive Enteral Nutrition in Patients With Ileocaecal Crohn's Disease (XENIC): an Open-label, Multicenter, Prospective, Randomized Clinical Trial | Crohn Disease;Nutrient; Excess;Remission/Regression | Dietary Supplement: EEN (Nestle Modulen®);Drug: Standart of care | Duzce University | NULL | Recruiting | 18 Years | 75 Years | All | 256 | Phase 3 | Turkey |
| 6 | NCT04398836 (ClinicalTrials.gov) | September 2020 | 18/7/2019 | Preoperative Nutrition for Crohn's Disease Patients | Preoperative Nutrition for Crohn's Disease Patients | Malnutrition;Crohn Disease | Dietary Supplement: Exclusive Enteral Nutrition;Other: High energy / protein diet.;Other: Standard nutrition | Tel-Aviv Sourasky Medical Center | NULL | Not yet recruiting | 18 Years | 70 Years | All | 144 | Phase 3 | Israel |
| 7 | NCT05321758 (ClinicalTrials.gov) | March 22, 2020 | 4/4/2022 | Fecal Microbiota Transplantation as the First-line Treatment in Active Pediatric Crohn's Disease | Repeated and Multiple Fecal Microbiota Transplantations Plus Partial Enteral Nutrition as the First-line Treatment in Active Pediatric Crohn's Disease | Crohn Disease | Biological: Fecal Microbiota Transplantation;Other: PEN | Tongji Hospital | NULL | Recruiting | 2 Years | 16 Years | All | 50 | N/A | China |
| 8 | NCT03833596 (ClinicalTrials.gov) | October 25, 2018 | 21/12/2018 | Exclusive Enteral Nutrition and Corticosteroids Therapy in Crohn's Disease (EENCD) | Synergistic Effect of Exclusive Enteral Nutrition Formula in Addition to Corticosteroids Therapy to Induce Clinical Remission in Patients With Crohn's Disease: a Pilot Study Involving a Multidimensional Assessment of Potential Mechanisms | Crohn's Disease | Drug: Prednisone;Dietary Supplement: Exclusive Enteral Nutrition | McMaster University | Nestlé | Terminated | 18 Years | 75 Years | All | 3 | Phase 4 | Canada |
| 9 | NCT04160325 (ClinicalTrials.gov) | May 14, 2018 | 3/11/2019 | Effect of the Exclusive Enteral Nutrition Combined With Azathioprine for Remission of Crohn's Diseases After Surgery | The Effect of the Exclusive Enteral Nutrition Combined With Azathioprine in Maintaining Remission of Patients With Crohn's Diseases After Surgery | Crohn Disease | Dietary Supplement: postoperative 3-month exclusive enteral nutrition;Drug: azathioprine;Other: normal diet | Zhu Weiming | Sixth Affiliated Hospital, Sun Yat-sen University;Sir Run Run Shaw Hospital;The First Affiliated Hospital of Anhui Medical University;Beijing Tsinghua Changgung Hospital | Recruiting | 18 Years | 65 Years | All | 198 | N/A | China |
| 10 | NCT03755583 (ClinicalTrials.gov) | February 1, 2017 | 18/11/2018 | Effect of Exclusive Enteral Nutrition on Disease Process, Nutritional Status and Gastrointestinal Microbiota for Chinese Children With Crohn's Disease | Effect of Exclusive Enteral Nutrition on Disease Process, Nutritional Status and Intestinal Microbiota for Chinese Children With Crohn's Disease | Crohn Disease;Enteral Nutrition;Gastrointestinal Microbiome | Dietary Supplement: Exclusive Enteral Nutrition | Children's Hospital of Fudan University | NULL | Completed | 1 Year | 17 Years | All | 31 | N/A | China |
| 11 | NCT02231814 (ClinicalTrials.gov) | December 2016 | 27/8/2014 | The Crohn's Disease Exclusion Diet With Partial Enteral Nutrition or Alone in Adult Patients With Crohn's Disease | Dietary Therapy Using the Crohn's Disease Exclusion Diet (CDED) With Partial Enteral Nutrition or Alone for Induction and Maintenance of Remission in in Adults With Mild to Moderate Crohn's Disease- A Pilot Study | Crohn's Disease | Dietary Supplement: Crohns Disease Exclusion Diet + PEN;Other: Crohns Disease Exclusion Diet | Prof. Arie Levine | NULL | Completed | 18 Years | 55 Years | All | 40 | N/A | Israel |
| 12 | NCT02998827 (ClinicalTrials.gov) | November 2016 | 24/11/2016 | Thalidomide Results in Diminished Ovarian Reserve in Reproductive Age Female IBD Patients | Crohn Disease | Drug: Thalidomide;Drug: infliximab, azathioprine;Other: enteral nutrition | Sixth Affiliated Hospital, Sun Yat-sen University | NULL | Enrolling by invitation | N/A | N/A | Female | 90 | N/A | NULL | |
| 13 | NCT02897661 (ClinicalTrials.gov) | August 2016 | 14/8/2016 | Washed Microbiota Transplantation Improves Nutritional Status of Patients With Crohn's Disease | Washed Microbiota Transplantation Combining Exclusive Enteral Nutrition Contribute to Nutritional Improvement of Patients With Crohns' Disease | Crohn's Diseases | Procedure: WMT;Dietary Supplement: EEN | The Second Hospital of Nanjing Medical University | NULL | Recruiting | 18 Years | 65 Years | All | 30 | N/A | China |
| 14 | NCT02517684 (ClinicalTrials.gov) | April 2015 | 1/7/2015 | Top-down Infliximab Study in Kids With Crohn's Disease | Top-down Infliximab Study in Kids With Crohn's Disease | Crohn's Disease | Drug: Infliximab;Drug: Prednisolone;Other: Exclusive enteral nutrition;Drug: Azathioprine | Erasmus Medical Center | ZonMw: The Netherlands Organisation for Health Research and Development;Hospira, now a wholly owned subsidiary of Pfizer | Active, not recruiting | 3 Years | 17 Years | All | 100 | Phase 4 | Belgium;Finland;Netherlands;Denmark;Italy;Poland |
| 15 | NCT02201693 (ClinicalTrials.gov) | December 12, 2014 | 17/7/2014 | Cyclic Exclusive Enteral Nutrition as Maintenance Therapy for Pediatric Crohn's Disease | Randomised Trial Comparing 12 Months of Cyclic Enteral Nutrition to Supplementary Enteral Nutrition as Maintenance Therapy for Pediatric Crohn's Disease | Crohn's Disease | Dietary Supplement: MODULEN IBD | Assistance Publique - Hôpitaux de Paris | GETAID Pediatric | Completed | 6 Years | 18 Years | All | 100 | N/A | France |
| 16 | NCT02056418 (ClinicalTrials.gov) | January 2014 | 24/1/2014 | Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in Adult | A Randomized, Controlled, Single-blind Study of Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in Adult | Crohn Disease | Dietary Supplement: enteral nutrition;Drug: corticosteroid | Jinling Hospital, China | NULL | Active, not recruiting | 18 Years | 75 Years | Both | 30 | Phase 4 | China |
| 17 | NCT02887287 (ClinicalTrials.gov) | July 2013 | 29/8/2016 | Efficacy of Exclusive Enteral Nutrition in Adult Active Crohn's Disease | Efficacy of Exclusive Enteral Nutrition in Adult Active Crohn's Disease With Complications or Failure of Medical Treatment | Drug: EEN | Sun Yat-sen University | NULL | Completed | 18 Years | 60 Years | Both | 48 | N/A | China | |
| 18 | NCT02233062 (ClinicalTrials.gov) | May 2013 | 1/9/2014 | Impact of Exclusive Enteral Nutrition Therapy on Sperm Quality of Patients With Crohn's Disease | Impact of Exclusive Enteral Nutrition Therapy on Sperm Quality of Male Patients With Crohn's Disease | Crohn's Disease | Dietary Supplement: Exclusive Enteral Nutrition Therapy | Jinling Hospital, China | NULL | Completed | 18 Years | 40 Years | Male | 12 | N/A | China |
| 19 | NCT01820247 (ClinicalTrials.gov) | December 2012 | 25/3/2013 | Efficacy Study of Tripterygium Glycoside Combined With Enteral Nutrition in the Treatment of Crohn's Disease for Induction Remission | Efficacy Study of Tripterygium Glycoside Combined With Enteral Nutrition in the Treatment of Crohn's Disease for Induction Remission | Crohn's Disease | Drug: enteral nutrition;Drug: Tripterygium glycosides | Zhu Weiming | NULL | Recruiting | 18 Years | 75 Years | Both | 100 | N/A | China |
| 20 | NCT01823029 (ClinicalTrials.gov) | November 2012 | 25/3/2013 | Oxidative Stress and Inflammation Caused by Intravenous Iron in Crohn's Disease Patients With Iron Deficiency Anemia | Crohn's Disease | Drug: erythropoietin;Drug: enteral nutrition.;Drug: injection of iron | Jinling Hospital, China | Ministry of Health, China | Completed | 18 Years | 75 Years | Both | 387 | N/A | China | |
| 21 | NCT01823042 (ClinicalTrials.gov) | October 2012 | 25/3/2013 | The Efficacy of Enteral Nutrition in Fill of the Treatment Blank Period of the Postoperative Maintain Remission Medication for Crohn's Disease (CD) | A Randomized, Controlled, Open-label Study to Assess the the Efficacy of Enteral Nutrition in Fill of the Treatment Blank Period of the Postoperative Maintain Remission Medication for Crohn's Disease (CD). | Crohn's Disease | Drug: azathioprine+enteral nutrition;Drug: Azathioprine | Jinling Hospital, China | NULL | Recruiting | 18 Years | 75 Years | Both | 100 | N/A | China |
| 22 | NCT00265772 (ClinicalTrials.gov) | November 2005 | 14/12/2005 | Comparison of a Nutritional Anti-Inflammatory Treatment to Steroids for Pediatric Crohn's Disease - the Molecular Basis | Phase IV Study Comparing a Nutritional Anti-Inflammatory Treatment to Steroids for Pediatric Crohn's Disease - the Molecular Basis | Crohn's Disease;Pediatric | Drug: MODULEN IBD (R) (specific Enteral Nutrition);Drug: prednisolon | Hôpital Necker-Enfants Malades | Institut National de la Santé Et de la Recherche Médicale, France;Nestlé | Recruiting | 6 Years | 18 Years | Both | 24 | Phase 4 | France |