MK-6194 ( DrugBank: - )


1 disease
IDDisease name (Link within this page)Number of trials
97Ulcerative colitis2

97. Ulcerative colitis


Clinical trials : 2,630 Drugs : 1,459 - (DrugBank : 265) / Drug target genes : 144 - Drug target pathways : 202
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PhaseCountries
1JPRN-jRCT2051210183
09/03/202202/03/2022Single Dose Study of MK-6194 in Healthy Japanese ParticipantsA Single Dose Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK-6194 in Healthy Japanese Participants Ulcerative colitis- Drug: MK-6194
MK-6194 1-7.5 mg subcutaneously administered in sterile solution form once
- Drug: Placebo
5% glucose subcutaneously administered in sterile solution form once
Tanaka YoshiyukiNULLRecruiting>= 20age old<= 55age oldMale48Phase 1Japan
2NCT04924114
(ClinicalTrials.gov)
October 14, 202126/2/2021A Study of MK-6194 (PT101) in Participants With Active Ulcerative Colitis (UC) (MK-6194-002)A Phase 1b, Randomized, Adaptive, Double-Blind, Placebo-Controlled, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of PT101 in Subjects With Active Ulcerative ColitisUlcerative ColitisDrug: MK-6194;Drug: MK-6194-matching placeboMerck Sharp & Dohme LLCNULLRecruiting18 Years80 YearsAll30Phase 1United States;Georgia;Germany;Hungary;Moldova, Republic of;Poland;Ukraine;United Kingdom