DDrare: Database of Drug Development for Rare Diseases

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No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	Carbidopa	Carbidopa	1件: D00558 💬	1件: DDC 💬	9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism	9件: 2 , 4 , 6 , 13, 17, 90, 140, 164, 201 💬
2	Carbidopa-levodopa	Carbidopa	2件: D00059, D00558 💬	6件: DDC, DRD1, DRD2, DRD3, DRD4, DRD5 💬	16件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway	3件: 2 , 4 , 6 💬
3	Dalfampridine	Dalfampridine	1件: D04127 💬	4件: KCNA4, KCNC3, KCND2, KCND3 💬	4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia	2件: 4 , 13 💬
4	Daraprim	-	-	-	-	2件: 2 , 4 💬
5	Dexdor	-	-	-	-	4件: 2 , 4 , 6 , 70 💬
6	Dexmedetomidine	Dexmedetomidine	2件: D00514, D01205 💬	3件: ADRA2A, ADRA2B, ADRA2C 💬	2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway	12件: 2 , 4 , 6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬
7	Esketamine	Esketamine	1件: D07283 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway	3件: 2 , 4 , 70 💬
8	Ketanest	-	-	-	-	3件: 2 , 4 , 70 💬
9	Ketanest-s	-	-	-	-	3件: 2 , 4 , 70 💬
10	Levetiracetam	Levetiracetam	1件: D00709 💬	1件: SV2A 💬	1件: ECM-receptor interaction	4件: 2 , 4 , 6 , 13 💬

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