DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adrenergic signaling in cardiomyocytes 💬	1件: ADRB1 💬	D00235 💬	Atenolol	1件: 167 💬
2	Adrenergic signaling in cardiomyocytes 💬	1件: ADRB1 💬	D05127 💬	Nebivolol	3件: 17, 113, 167 💬
3	Adrenergic signaling in cardiomyocytes 💬	2件: ADRB1, ADRB2 💬	D00483 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
4	Adrenergic signaling in cardiomyocytes 💬	2件: ADRB1, ADRB2 💬	D08443 💬	Propranolol	6件: 6 , 158, 167, 227, 278, 296 💬
5	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
6	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
7	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
8	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00619 💬	Verapamil	3件: 96, 140, 167 💬
9	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D02356 💬	Verapamil	3件: 96, 140, 167 💬
10	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬

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