DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adherens junction 💬	1件: IGF1R 💬	D03297 💬	Mecasermin	6件: 65, 78, 96, 168, 265, 299 💬
2	Adherens junction 💬	1件: IGF1R 💬	D04870 💬	Mecasermin	6件: 65, 78, 96, 168, 265, 299 💬
3	Adrenergic signaling in cardiomyocytes 💬	1件: ADRB1 💬	D07660 💬	Celiprolol	1件: 168 💬
4	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬
5	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D01450 💬	Bupivacaine	8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
6	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D07552 💬	Bupivacaine	8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
7	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D00358 💬	Lidocaine	12件: 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
8	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D02086 💬	Lidocaine	12件: 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
9	Adrenergic signaling in cardiomyocytes 💬	1件: SCN5A 💬	D08127 💬	Lidocaine	12件: 6 , 13, 34, 46, 51, 70, 84, 86, 168, 226, 231, 256 💬
10	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D00523 💬	Irbesartan	4件: 66, 167, 168, 222 💬

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