DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Acute myeloid leukemia 💬	1件: MPO 💬	D11684 💬	Verdiperstat	2件: 2 , 17 💬
2	Acute myeloid leukemia 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
3	Adipocytokine signaling pathway 💬	1件: MTOR 💬	D00753 💬	Sirolimus	40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
4	Adrenergic signaling in cardiomyocytes 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D01307 💬	Midodrine	3件: 6 , 17, 58 💬
5	Adrenergic signaling in cardiomyocytes 💬	3件: ADRA1A, ADRA1B, ADRA1D 💬	D08220 💬	Midodrine	3件: 6 , 17, 58 💬
6	Adrenergic signaling in cardiomyocytes 💬	5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D01277 💬	Droxidopa	3件: 5 , 6 , 17 💬
7	Adrenergic signaling in cardiomyocytes 💬	5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D00485 💬	Pseudoephedrine	1件: 17 💬
8	Adrenergic signaling in cardiomyocytes 💬	5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D05648 💬	Pseudoephedrine	1件: 17 💬
9	Adrenergic signaling in cardiomyocytes 💬	5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D05649 💬	Pseudoephedrine	1件: 17 💬
10	Adrenergic signaling in cardiomyocytes 💬	5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	D08449 💬	Pseudoephedrine	1件: 17 💬

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