DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	ABC transporters 💬	1件: ABCC8 💬	D00418 💬	Minoxidil	1件: 179 💬
2	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
3	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
4	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
5	AGE-RAGE signaling pathway in diabetic complications 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
6	Alcoholism 💬	1件: DRD2 💬	D00426 💬	Risperidone	5件: 8 , 156, 179, 187, 206 💬
7	Alcoholism 💬	1件: SLC6A3 💬	D01296 💬	Methylphenidate	7件: 6 , 13, 34, 84, 113, 179, 206 💬
8	Alcoholism 💬	1件: SLC6A3 💬	D04999 💬	Methylphenidate	7件: 6 , 13, 34, 84, 113, 179, 206 💬
9	Aldosterone synthesis and secretion 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
10	Aldosterone synthesis and secretion 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬

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