DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adrenergic signaling in cardiomyocytes 💬	1件: ADRB2 💬	D02147 💬	Salbutamol	14件: 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
2	Alanine, aspartate and glutamate metabolism 💬	4件: ABAT, ALDH5A1, GAD1, GAD2 💬	D00399 💬	Valproic acid	16件: 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬
3	Alcoholism 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	8件: 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬
4	Aldosterone synthesis and secretion 💬	3件: CACNA1G, CACNA1H, CACNA1I 💬	D00399 💬	Valproic acid	16件: 2 , 3 , 5 , 6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬
5	Alzheimer disease 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	8件: 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬
6	Alzheimer disease 💬	1件: PTGS2 💬	D00217 💬	Acetaminophen	16件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬
7	Alzheimer disease 💬	1件: PTGS2 💬	D00567 💬	Celecoxib	9件: 2 , 3 , 34, 46, 70, 89, 161, 171, 271 💬
8	Amphetamine addiction 💬	9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	8件: 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬
9	Amyotrophic lateral sclerosis 💬	7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00775 💬	Riluzole	8件: 2 , 3 , 5 , 8 , 13, 17, 18, 206 💬
10	Arachidonic acid metabolism 💬	2件: PTGS1, PTGS2 💬	D00217 💬	Acetaminophen	16件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271 💬

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