DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adherens junction 💬	1件: IGF1R 💬	D03297 💬	Mecasermin	6件: 65, 78, 96, 168, 265, 299 💬
2	Adherens junction 💬	1件: IGF1R 💬	D04870 💬	Mecasermin	6件: 65, 78, 96, 168, 265, 299 💬
3	Alcoholism 💬	1件: ADORA2A 💬	D00528 💬	Caffeine	9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬
4	Alcoholism 💬	1件: ADORA2A 💬	D01453 💬	Caffeine	9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬
5	Alcoholism 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D00848 💬	Dextromethorphan	11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
6	Alcoholism 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D03742 💬	Dextromethorphan	11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
7	Alcoholism 💬	5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	D03744 💬	Dextromethorphan	11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
8	Aldosterone synthesis and secretion 💬	1件: MC2R 💬	D00146 💬	Corticotropin	13件: 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
9	Aldosterone synthesis and secretion 💬	1件: MC2R 💬	D00284 💬	Tetracosactide	5件: 78, 83, 113, 145, 222 💬
10	Aldosterone synthesis and secretion 💬	1件: PDE2A 💬	D00528 💬	Caffeine	9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬

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