DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adipocytokine signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D00944 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
2	Adipocytokine signaling pathway 💬	2件: PRKAA1, PRKAA2 💬	D04966 💬	Metformin	21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
3	Adrenergic signaling in cardiomyocytes 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00437 💬	Nifedipine	2件: 50, 81 💬
4	Aldosterone synthesis and secretion 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00437 💬	Nifedipine	2件: 50, 81 💬
5	Aldosterone-regulated sodium reabsorption 💬	1件: NR3C2 💬	D00986 💬	Fludrocortisone	3件: 6 , 17, 81 💬
6	Aldosterone-regulated sodium reabsorption 💬	1件: NR3C2 💬	D07967 💬	Fludrocortisone	3件: 6 , 17, 81 💬
7	Alzheimer disease 💬	4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00437 💬	Nifedipine	2件: 50, 81 💬
8	Amphetamine addiction 💬	2件: CACNA1C, CACNA1D 💬	D00437 💬	Nifedipine	2件: 50, 81 💬
9	AMPK signaling pathway 💬	1件: PPARG 💬	D00945 💬	Pioglitazone	17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
10	AMPK signaling pathway 💬	1件: PPARG 💬	D08378 💬	Pioglitazone	17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬

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