DDrare: Database of Drug Development for Rare Diseases

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Target Gene/Pathway（薬物標的遺伝子／パスウェイリスト）💬 Info on mouse-over

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	指定難病告示番号
1	Adipocytokine signaling pathway 💬	1件: JAK2 💬	D09970 💬	Tofacitinib	12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
2	Adipocytokine signaling pathway 💬	1件: PRKCQ 💬	D09671 💬	Sotrastaurin	1件: 97 💬
3	Adipocytokine signaling pathway 💬	1件: TNF 💬	D02597 💬	Adalimumab	16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬
4	Adipocytokine signaling pathway 💬	1件: TNF 💬	D03441 💬	Certolizumab pegol	6件: 37, 46, 96, 97, 226, 271 💬
5	Adipocytokine signaling pathway 💬	1件: TNF 💬	D04358 💬	Golimumab	6件: 46, 56, 84, 96, 97, 271 💬
6	Adipocytokine signaling pathway 💬	1件: TNF 💬	D02598 💬	Infliximab	25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
7	Adipocytokine signaling pathway 💬	1件: TNF 💬	D00754 💬	Thalidomide	20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
8	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D00357 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
9	Adrenergic signaling in cardiomyocytes 💬	1件: AGTR1 💬	D08146 💬	Losartan	18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
10	African trypanosomiasis 💬	2件: IL12A, IL12B 💬	D09214 💬	Ustekinumab	15件: 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬

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