DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Alanine, aspartate and glutamate metabolism 💬	[1] ABAT 💬	D00535 💬	Vigabatrin	[2] 145, 158 💬
2	Aldosterone synthesis and secretion 💬	[1] MC2R 💬	D00146 💬	Corticotropin	[13] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
3	Aldosterone synthesis and secretion 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
4	beta-Alanine metabolism 💬	[1] ABAT 💬	D00535 💬	Vigabatrin	[2] 145, 158 💬
5	Butanoate metabolism 💬	[1] ABAT 💬	D00535 💬	Vigabatrin	[2] 145, 158 💬
6	Calcium signaling pathway 💬	[3] HTR2A, HTR2B, HTR2C 💬	D07945 💬	Fenfluramine	[3] 140, 144, 145 💬
7	cAMP signaling pathway 💬	[1] MC2R 💬	D00146 💬	Corticotropin	[13] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
8	cAMP signaling pathway 💬	[1] MC2R 💬	D00284 💬	Tetracosactide	[5] 78, 83, 113, 145, 222 💬
9	Circadian entrainment 💬	[2] MTNR1A, MTNR1B 💬	D08170 💬	Melatonin	[11] 6 , 8 , 13, 46, 49, 90, 97, 144, 145, 149, 202 💬
10	Cortisol synthesis and secretion 💬	[1] MC2R 💬	D00146 💬	Corticotropin	[13] 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬

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