DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬	D00680 💬	Methylergometrine	[2] 118, 288 💬
2	Adrenergic signaling in cardiomyocytes 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬	D08207 💬	Methylergometrine	[2] 118, 288 💬
3	Alzheimer disease 💬	[1] PSMB5 💬	D03150 💬	Bortezomib	[15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
4	AMPK signaling pathway 💬	[1] ADRA1A 💬	D00680 💬	Methylergometrine	[2] 118, 288 💬
5	AMPK signaling pathway 💬	[1] ADRA1A 💬	D08207 💬	Methylergometrine	[2] 118, 288 💬
6	AMPK signaling pathway 💬	[1] HMGCR 💬	D00434 💬	Simvastatin	[21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
7	Amyotrophic lateral sclerosis 💬	[1] PSMB5 💬	D03150 💬	Bortezomib	[15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
8	Bile secretion 💬	[1] HMGCR 💬	D00434 💬	Simvastatin	[21] 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
9	Calcium signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬	D00680 💬	Methylergometrine	[2] 118, 288 💬
10	Calcium signaling pathway 💬	[3] ADRA1A, ADRA1B, ADRA1D 💬	D08207 💬	Methylergometrine	[2] 118, 288 💬

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