DDrare: Database of Drug Development for Rare Diseases

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adipocytokine signaling pathway 💬	[1] JAK2 💬	D10308 💬	Baricitinib	[9] 41, 46, 49, 50, 93, 107, 265, 268, 325 💬
2	Adipocytokine signaling pathway 💬	[1] JAK2 💬	D09970 💬	Tofacitinib	[12] 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬
3	Adipocytokine signaling pathway 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
4	Adipocytokine signaling pathway 💬	[1] TNF 💬	D02598 💬	Infliximab	[25] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬
5	Adipocytokine signaling pathway 💬	[1] TNF 💬	D01583 💬	Pirfenidone	[10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
6	Adrenergic signaling in cardiomyocytes 💬	[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬	D00437 💬	Nifedipine	[2] 50, 81 💬
7	African trypanosomiasis 💬	[4] IL10, IL1B, IL6, TNF 💬	D01583 💬	Pirfenidone	[10] 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
8	African trypanosomiasis 💬	[2] IL12A, IL12B 💬	D09214 💬	Ustekinumab	[15] 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 💬
9	African trypanosomiasis 💬	[1] IL1B 💬	D09911 💬	Gevokizumab	[4] 41, 50, 56, 269 💬
10	African trypanosomiasis 💬	[1] TNF 💬	D00742 💬	Etanercept	[15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬

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