DDrare: Database of Drug Development for Rare Diseases

Searched query = "Hemiconvulsion hemiplegia epilepsy syndrome", "One side convulsions", "Hemiplegia", "Epilepsy syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = 4cc of lidocaïne®; 9060X; BOTOX; BOTULINUM TOXIN TYPE A; Baclofen; Balance; Botox; Botulinum toxin; Botulinum toxin A; Botulinum toxin type A; Brivaracetam; Diagnostic Test: Nociceptor flexor reflex; Diagnostic Test: gait analysis; Edonerpic; Gradient; HC-58; Lacosamide; MEOPA; Medicinal air; Melatonin; Other: Review of past medical history, clinical exam, and electroencephalogram, polysomnography and urine samples of melatonin and pupillometry.; Other: The patients' parents have to complete the VINELAND II adaptive behavior scales scoring, The Sleep Disturbance Scale for Children (SDSC) and Horne & Ostberg Circadian Typology Questionnaire; Oxybate; Padsevonil; Placebo; Procedure: upper limb muscle block; SPM927; Sodium Oxybate; Sodium oxybate; T-817MA; Time delay treatment of botulinum toxin; Triheptanoin; Ucb 34714

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04630873 (ClinicalTrials.gov)	November 20, 2020	31/10/2020	Low or High Botox Dilution for the Hemiplegic Gait?	Different Dilutions and Efficacy of Botulin Toxin in the Correction of the Hemiplegic Gait	Post Stroke Spastic Hemiplegia	Drug: Botulinum toxin;Diagnostic Test: gait analysis	University of Ioannina	NULL	Recruiting	18 Years	N/A	All	20	Phase 1	Greece
2	NCT03860662 (ClinicalTrials.gov)	February 26, 2019	8/2/2019	Nociceptive Flexor Reflex and Antispastic Treatmens	Research Assistant Doctor	Stroke Sequelae;Spastic Hemiplegia	Diagnostic Test: Nociceptor flexor reflex;Drug: Botox;Drug: Baclofen	Mustafa Kemal University	NULL	Not yet recruiting	18 Years	60 Years	All	30	Phase 4	Turkey
3	EUCTR2009-015620-29-BE (EUCTR)	08/03/2010	09/02/2010	The efficacy of the Botulinum toxin-A on the manual abilities in children with congenital spastic hemiplegia. Interest of the measure of the bimanual task performance.	The efficacy of the Botulinum toxin-A on the manual abilities in children with congenital spastic hemiplegia. Interest of the measure of the bimanual task performance.	The main objective of this study is to investigate the effect of Botulinum toxin A to improve the Upper Limb dysfunction in Hemiplegic Cerebral Palsy Children and in particular, its impact on Upper limb activity performance and how this might be translate in bimanual activities. MedDRA version: 12.0;Level: LLT;Classification code 10019475;Term: Hemiplegic infantile cerebral palsy	Trade Name: BOTOX Product Name: BOTOX Product Code: 9060X Other descriptive name: BOTULINUM TOXIN TYPE A		NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	30		Belgium

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT04630873
(ClinicalTrials.gov)

November 20, 2020

31/10/2020

Low or High Botox Dilution for the Hemiplegic Gait?

Different Dilutions and Efficacy of Botulin Toxin in the Correction of the Hemiplegic Gait

Post Stroke Spastic Hemiplegia

Drug: Botulinum toxin;Diagnostic Test: gait analysis

University of Ioannina

NULL

Recruiting

18 Years

N/A

All

Phase 1

Greece

NCT03860662
(ClinicalTrials.gov)

February 26, 2019

8/2/2019

Nociceptive Flexor Reflex and Antispastic Treatmens

Research Assistant Doctor

Stroke Sequelae;Spastic Hemiplegia

Diagnostic Test: Nociceptor flexor reflex;Drug: Botox;Drug: Baclofen

Mustafa Kemal University

NULL

Not yet recruiting

18 Years

60 Years

All

Phase 4

Turkey

EUCTR2009-015620-29-BE
(EUCTR)

08/03/2010

09/02/2010

The efficacy of the Botulinum toxin-A on the manual abilities in children with congenital spastic hemiplegia. Interest of the measure of the bimanual task performance.

The main objective of this study is to investigate the effect of Botulinum toxin A to improve the Upper Limb dysfunction in Hemiplegic Cerebral Palsy Children and in particular, its impact on Upper limb activity performance and how this might be translate in bimanual activities.
MedDRA version: 12.0;Level: LLT;Classification code 10019475;Term: Hemiplegic infantile cerebral palsy

Trade Name: BOTOX
Product Name: BOTOX
Product Code: 9060X
Other descriptive name: BOTULINUM TOXIN TYPE A

NULL

Authorised-recruitment may be ongoing or finished

Female: yes
Male: yes

Belgium