51. Scleroderma
466 clinical trials, 536 drugs (DrugBank: 142 drugs), 110 drug target genes, 210 drug target pathways
Searched query = "Scleroderma", "Systemic sclerosis", "SSc", "dcSSc", "lcSSc"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT00577304 (ClinicalTrials.gov) | December 2007 | 18/12/2007 | A Study of a Topical Form of Nitroglycerin and Placebo in the Treatment and Prevention of Raynaud's Phenomenon | A Study of a Topical Formulation of Nitroglycerin, MQX-503, and Matching Vehicle in the Treatment and Prevention of Raynaud's Phenomenon | Raynaud's Disease;Raynaud's Disease Secondary to Scleroderma;Raynaud's Disease Secondary to Other Autoimmune Disease | Drug: Nitroglycerin;Drug: Topical AmphiMatrix | MediQuest Therapeutics | NULL | Active, not recruiting | 15 Years | 70 Years | Both | 200 | Phase 3 | United States |
| 2 | NCT00419419 (ClinicalTrials.gov) | December 2006 | 4/1/2007 | Phase III Study of a Topical Gel Formulation for Treatment and Prevention of Raynaud's Phenomenon | Phase III In-Life Study of a Topical Gel Formulation of Nitroglycerin, MQX-503, and Matching Placebo Gel in the Treatment and Prevention of Raynaud's Phenomenon | Raynaud's Disease;Scleroderma;Autoimmune Diseases | Drug: Topical AmphiMatrix with nitroglycerin (MQX-503) | MediQuest Therapeutics | NULL | Completed | 18 Years | 70 Years | Both | 80 | Phase 3 | United States;Sweden;United Kingdom |
| 3 | EUCTR2005-004979-37-GB (EUCTR) | 27/11/2006 | 18/09/2006 | Phase III In-Life” Study of a Topical Gel Formulation of Nitroglycerin, MQX-503, and Matching Placebo Gel in the Treatment and Prevention of Raynaud’s Phenomenon - 06-004 A2 | Phase III In-Life” Study of a Topical Gel Formulation of Nitroglycerin, MQX-503, and Matching Placebo Gel in the Treatment and Prevention of Raynaud’s Phenomenon - 06-004 A2 | Moderate to severe primary Raynaud’s, OR patients with Raynaud’s phenomenon secondary to autoimmune diseases, such as scleroderma | MediQuest Therapeutics, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 100 | Phase 3 | United Kingdom;Sweden | |||
| 4 | EUCTR2005-004979-37-SE (EUCTR) | 27/10/2006 | 08/09/2006 | Phase III In-Life” Study of a Topical Gel Formulation of Nitroglycerin, MQX-503, and Matching Placebo Gel in the Treatment and Prevention of Raynaud’s Phenomenon - 06-004 A2 | Phase III In-Life” Study of a Topical Gel Formulation of Nitroglycerin, MQX-503, and Matching Placebo Gel in the Treatment and Prevention of Raynaud’s Phenomenon - 06-004 A2 | Moderate to severe primary Raynaud’s,OR patients with Raynaud’s phenomenon secondary to autoimmune diseases, such as scleroderma | Product Name: MQX-503 Product Code: MQX-503 INN or Proposed INN: 10% Nitroglycerine in Propylene Glycol, USP Other descriptive name: Nitroglycerine gel | MediQuest Therapeutics, Inc. | NULL | Not Recruiting | Female: yes Male: yes | 100 | Phase 3 | United Kingdom;Sweden | ||
| 5 | NCT00378521 (ClinicalTrials.gov) | July 2006 | 18/9/2006 | Dose Response Study of a Topical Gel for the Treatment of Raynaud's Phenomenon | Phase II Dose Response Study of a Topical Gel Formulation of Nitroglycerin, MQX-503, in the Treatment of Raynaud's Phenomenon | Raynaud's Disease;Raynaud's Disease Secondary to Scleroderma;Raynaud's Disease Secondary to Autoimmune Disease | Drug: MQX-503 | MediQuest Therapeutics | NULL | Completed | 18 Years | 75 Years | Both | 15 | Phase 2 | United States |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | NCT00253331 (ClinicalTrials.gov) | November 2004 | 13/11/2005 | Lab Study of MQX-503 in Treatment of Raynaud's | Phase III Laboratory Study of a Topical Gel Formulation of Nitroglycerin, MQX-503, in the Treatment of Raynaud’s Phenomenon | Raynaud Disease;Raynaud Disease Secondary to Scleroderma;Raynaud Secondary to Other Autoimmune Disease | Drug: topical organogel with nitroglycerin | MediQuest Therapeutics | NULL | Completed | 18 Years | 80 Years | Both | 36 | Phase 2;Phase 3 | United States |