DDrare: Database of Drug Development for Rare Diseases

Searched query = "Pituitary ADH secretion disorder", "Inappropriate antidiuretic hormone secretion", "Syndrome of inappropriate secretion of antidiuretic hormone", "Inappropriate ADH syndrome", "Syndrome of inappropriate ADH", "Central diabetes insipidus", "Syndrome of inappropriate secretion of ADH", "SIADH"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = C03XA01; Desmopressin; Desmopressin Oral Melt; Desmopressin intranasal; Empagliflozin; Empagliflozin 25 MG; Empagliflozin 25mg; Empagliflozin 25mg Tbl; IUPAC; Other: Fluid Restriction; Other: Induced hypotonic hyponatremia - SIAD model; SAMSCA*10CPR 15MG; SR121463B; Samsca; Satavaptan; Satavaptan (SR121463); Satavaptan (SR121463B); TOLVAPTAN; Tolvaptan; Tolvaptan Oral Tablet; Tolvaptan in euvolemic hyponatremia; Urea

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00728091 (ClinicalTrials.gov)	July 2008	31/7/2008	A Phase III Study Evaluating the Efficacy and Safety of Satavaptan Versus Placebo in Patients With Dilutional Hyponatremia	A Double-Blind, Randomized, Placebo-Controlled Multicenter Study Evaluating the Efficacy and Safety of Two Doses of Satavaptan (SR121463B) Versus Placebo in Patients With Dilutional Hyponatremia Due to the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)	Hyponatremia;Inappropriate ADH Syndrome	Drug: satavaptan (SR121463);Drug: placebo	Sanofi	NULL	Terminated	18 Years	N/A	Both	2	Phase 3	United States

No.

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registration

Public_title

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Condition

Intervention

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sponsor

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sponsor

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Inclusion_
agemin

Inclusion_
agemax

Inclusion_
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NCT00728091
(ClinicalTrials.gov)

July 2008

31/7/2008

A Phase III Study Evaluating the Efficacy and Safety of Satavaptan Versus Placebo in Patients With Dilutional Hyponatremia

A Double-Blind, Randomized, Placebo-Controlled Multicenter Study Evaluating the Efficacy and Safety of Two Doses of Satavaptan (SR121463B) Versus Placebo in Patients With Dilutional Hyponatremia Due to the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Hyponatremia;Inappropriate ADH Syndrome

Drug: satavaptan (SR121463);Drug: placebo

Sanofi

NULL

Terminated

18 Years

N/A

Both

Phase 3

United States