Vorinostat    (DrugBank: Vorinostat)

3 diseases
告示番号疾患名(ページ内リンク)臨床試験数
19ライソゾーム病1
75クッシング病1
96クローン病1

19. ライソゾーム病 [臨床試験数:784,薬物数:673(DrugBank:101),標的遺伝子数:68,標的パスウェイ数:184
Searched query = "Lysosomal storage disease", "Lysosomal disease", "Gaucher disease", "Niemann-Pick disease", "Niemann-Pick type C", "GM1-gangliosidosis", "GM1-gangliosidoses", "GM2-gangliosidosis", "GM2-gangliosidoses", "Tay-Sachs disease", "Sandhoff disease", "Krabbe disease", "Metachromatic leukodystrophy", "Multiple-sulfatase deficiency", "Farber disease", "Mucopolysaccharidosis type I", "Mucopolysaccharidosis I", "MPS I", "Hurler syndrome", "Scheie syndrome", "Mucopolysaccharidosis type II", "Mucopolysaccharidosis II", "MPS II", "Hunter syndrome", "Mucopolysaccharidosis type III", "Mucopolysaccharidosis III", "MPS III", "Sanfilippo syndrome", "Mucopolysaccharidosis type IV", "Mucopolysaccharidosis IV", "MPS IV", "MPS IVA", "Morquio syndrome", "Morquio A syndrome", "Mucopolysaccharidosis type VI", "Mucopolysaccharidosis VI", "MPS VI", "Maroteaux-Lamy syndrome", "Mucopolysaccharidosis type VII", "Mucopolysaccharidosis VII", "MPS VII", "Sly syndrome", "Mucopolysaccharidosis type IX", "Mucopolysaccharidosis IX", "MPS IX", "Hyaluronidase deficiency", "Sialidosis", "Galactosialidosis", "Mucolipidosis II", "Mucolipidosis type II", "I-cell disease", "Mucolipidosis III", "Mucolipidosis type III", "Alpha-Mannosidosis", "Alpha-Mannosidase Deficiency", "Beta-Mannosidosis", "Beta-Mannosidase Deficiency", "Fucosidosis", "Aspartylglucosaminuria", "Schindler disease", "Kanzaki disease", "Pompe disease", "Acid lipase deficiency", "Wolman disease", "Cholesterol ester storage disease", "Danon disease", "Free sialic acid storage disease", "Salla disease", "Ceroid lipofuscinosis", "Fabry disease", "Cystinosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 784 trial found
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PhaseCountries
1NCT02124083
(ClinicalTrials.gov)
April 25, 201425/4/2014Phase 1/2 Study of Vorinostat Therapy in Niemann-Pick Disease, Type C1Phase 1/2 Study of Vorinostat Therapy in Niemann-Pick Disease, Type C1Neimann-Pick DiseaseDrug: VorinostatEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Washington University School of Medicine;Weill Medical College of Cornell UniversityCompleted18 Years60 YearsAll12Phase 1;Phase 2United States

75. クッシング病 [臨床試験数:191,薬物数:172(DrugBank:48),標的遺伝子数:61,標的パスウェイ数:121
Searched query = "Cushing disease", "Cushing"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 191 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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agemin
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agemax
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PhaseCountries
1NCT04339751
(ClinicalTrials.gov)
December 17, 20208/4/2020Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing s DiseaseThe Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing s DiseaseCushing's DiseaseDrug: VorinostatNational Institute of Neurological Disorders and Stroke (NINDS)NULLRecruiting18 YearsN/AAll22Phase 2United States

96. クローン病 [臨床試験数:2,209,薬物数:1,276(DrugBank:240),標的遺伝子数:166,標的パスウェイ数:210
Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 2,209 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
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Inclusion_
agemin
Inclusion_
agemax
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gender
Target_
size
PhaseCountries
1NCT03167437
(ClinicalTrials.gov)
October 30, 201724/5/2017Safety and Tolerability of Vorinostat for the Treatment of Moderate-to-Severe Crohn s DiseaseAn Open-Label, Phase I/II Pilot Study to Assess the Safety and Tolerability of Vorinostat for the Treatment of Moderate-to-Severe Crohn s DiseaseCrohn's DiseaseDrug: VorinostatNational Institute of Allergy and Infectious Diseases (NIAID)NULLRecruiting18 Years65 YearsAll35Phase 1;Phase 2United States