Regn2477    (DrugBank: -)

1 disease
告示番号疾患名(ページ内リンク)臨床試験数
272進行性骨化性線維異形成症5

272. 進行性骨化性線維異形成症 [臨床試験数:23,薬物数:21(DrugBank:4),標的遺伝子数:10,標的パスウェイ数:87
Searched query = "Fibrodysplasia ossificans progressiva", "FOP"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
5 / 23 trials found
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PhaseCountries
1EUCTR2016-005035-33-ES
(EUCTR)
17/01/201922/01/2019A study to examine the safety, tolerability and effects on abnormal bone formation of REGN2477 in patients with Fibrodysplasia Ossificans ProgressivaA randomized, placebo-controlled study to assess the safety, tolerability, pharmacokinetics, and effects on heterotopic bone formation of REGN2477 in patients with Fibrodysplasia Ossificans Progressiva - LUMINA-1 Fibrodysplasia Ossificans Progressiva (FOP)
MedDRA version: 20.0;Level: PT;Classification code 10068715;Term: Fibrodysplasia ossificans progressiva;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]
Product Name: REGN2477
Product Code: REGN2477
INN or Proposed INN: N/A
Other descriptive name: REGN2477
Regeneron Pharmaceuticals, Inc.NULLNot RecruitingFemale: yes
Male: yes
40Phase 2United States;France;Mexico;Canada;Poland;Spain;Netherlands;Colombia;United Kingdom;Italy
2EUCTR2016-005035-33-NL
(EUCTR)
05/03/201804/07/2017A study to examine the safety, tolerability and effects on abnormal bone formation of REGN2477 in patients with Fibrodysplasia Ossificans ProgressivaA randomized, placebo-controlled study to assess the safety, tolerability, pharmacokinetics, and effects on heterotopic bone formation of REGN2477 in patients with Fibrodysplasia Ossificans Progressiva - LUMINA-1 Fibrodysplasia Ossificans Progressiva (FOP)
MedDRA version: 20.0;Level: PT;Classification code 10068715;Term: Fibrodysplasia ossificans progressiva;System Organ Class: 10010331 - Congenital, familial and genetic disorders ;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]
Regeneron Pharmaceuticals, Inc.NULLAuthorised-recruitment may be ongoing or finished Female: yes
Male: yes
40Phase 2France;United States;Argentina;Spain;Brazil;Netherlands;Italy;United Kingdom
3NCT03188666
(ClinicalTrials.gov)
February 26, 201813/6/2017A Study to Examine the Safety, Tolerability and Effects on Abnormal Bone Formation of REGN2477 in Patients With Fibrodysplasia Ossificans ProgressivaA Randomized, Placebo-controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Effects on Heterotopic Bone Formation of REGN2477 in Patients With Fibrodysplasia Ossificans ProgressivaFibrodysplasia Ossificans ProgressivaDrug: REGN2477;Drug: Matching placeboRegeneron PharmaceuticalsNULLActive, not recruiting18 Years60 YearsAll44Phase 2United States;Canada;France;Italy;Netherlands;Poland;Spain;United Kingdom;Colombia
4EUCTR2016-005035-33-IT
(EUCTR)
15/12/201708/03/2018A study to examine the safety, tolerability and effects on abnormal bone formation of REGN2477 in patients with Fibrodysplasia Ossificans ProgressivaA randomized, placebo-controlled study to assess the safety, tolerability,pharmacokinetics, and effects on heterotopic bone formation of REGN2477in patients with Fibrodysplasia Ossificans Progressiva - LUMINA-1 Fibrodysplasia Ossificans Progressiva (FOP)
MedDRA version: 20.0;Level: PT;Classification code 10068715;Term: Fibrodysplasia ossificans progressiva;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]
Product Name: REGN2477
Product Code: REGN2477
Other descriptive name: REGN2477
REGENERON PHARMACEUTICALS, INC.NULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
40Phase 2France;United States;Argentina;Brazil;Netherlands;United Kingdom;Italy
5EUCTR2016-005035-33-GB
(EUCTR)
15/08/201722/05/2017A study to examine the safety, tolerability and effects on abnormal bone formation of REGN2477 in patients with Fibrodysplasia Ossificans ProgressivaA randomized, placebo-controlled study to assess the safety, tolerability, pharmacokinetics, and effects on heterotopic bone formation of REGN2477 in patients with Fibrodysplasia Ossificans Progressiva - LUMINA-1 Fibrodysplasia Ossificans Progressiva (FOP)
MedDRA version: 20.0;Level: PT;Classification code 10068715;Term: Fibrodysplasia ossificans progressiva;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]
Product Name: REGN2477
Product Code: REGN2477
INN or Proposed INN: N/A
Other descriptive name: REGN2477
Regeneron Pharmaceuticals, Inc.NULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
40Phase 2United States;France;Mexico;Canada;Spain;Poland;Netherlands;Colombia;Italy;United Kingdom