Neofuse (DrugBank: -)
1 disease| ID | Disease name (Link within this page) | Number of trials |
|---|---|---|
| 70 | Spinal stenosis | 5 |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT01106417 (ClinicalTrials.gov) | June 2010 | 16/4/2010 | Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion | Phase 2 Study Evaluating Safety and Preliminary Efficacy of NeoFuse When Combined With MasterGraft Matrix in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion With Anterior Cervical Plate Fixation | Cervical Degenerative Disc Disease;Degenerative Spondylolisthesis;Spinal Stenosis | Biological: NeoFuse;Device: MasterGraft Granules | Mesoblast, Ltd. | NULL | Completed | 18 Years | 70 Years | All | 12 | Phase 1;Phase 2 | Australia |
| 2 | NCT01097486 (ClinicalTrials.gov) | June 2010 | 30/3/2010 | Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy | Phase 2 Study Evaluating Safety and Preliminary Efficacy of NeoFuse When Combined With MasterGraft Matrix in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion With Anterior Cervical Plate Fixation | Cervical Degenerative Disc Disease;Degenerative Spondylolisthesis;Spinal Stenosis | Biological: NeoFuse;Procedure: Allograft | Mesoblast, Ltd. | NULL | Completed | 18 Years | 70 Years | All | 24 | Phase 2 | United States |
| 3 | NCT00996073 (ClinicalTrials.gov) | September 2009 | 9/10/2009 | Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion | A Prospective, Multicenter, Randomized, Open-Label, Controlled Study Evaluating Safety and Preliminary Efficacy of NeoFuse When Combined With MasterGraft Matrix in Subjects Undergoing Lumbar Interbody Fusion With Instrumentation | Degenerative Disc Disease;Degenerative Spondylolisthesis;Spinal Stenosis | Biological: Lumbar Interbody Fusion with Autograft;Biological: Lumbar Interbody Fusion with NeoFuse | Mesoblast, Ltd. | NULL | Completed | 18 Years | 70 Years | All | 24 | Phase 2 | United States |
| 4 | NCT00810212 (ClinicalTrials.gov) | November 2008 | 17/12/2008 | Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion | A Prospective, Multicenter, Randomized, Open-Label, Controlled Study Evaluating Safety and Preliminary Efficacy of NeoFuse When Combined With Mastergraft Granules in Subjects Undergoing Posterolateral Lumbar Fusion With Instrumentation | Degenerative Disc Disease;Degenerative Spondylolisthesis;Spinal Stenosis | Procedure: PLF with autograft;Biological: PLF with NeoFuse | Mesoblast, Ltd. | NULL | Withdrawn | 18 Years | 70 Years | All | 0 | Phase 1;Phase 2 | United States |
| 5 | NCT00549913 (ClinicalTrials.gov) | October 2007 | 24/10/2007 | Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) | A Dose-escalation Study to Assess the Feasibility and Safety of 3 Different Doses of NeoFuse When Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion With Instrumentation. | Degenerative Disc Disease;Spondylolisthesis;Spinal Stenosis | Biological: NeoFuse;Procedure: posterolateral spinal fusion with instrumentation | Mesoblast, Ltd. | NULL | Completed | 18 Years | N/A | All | 6 | Phase 1;Phase 2 | United States |