Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1100 mg ELX (VX-445) / 50 mg TEZ / 75 mg IVA FDC----[1] 299
2100 mg ELX /50 mg TEZ /75 mg IVA FDC----[1] 299
3100 mg ELX/50 mg TEZ /75 mg IVA FDC----[1] 299
4100 mg ELX/50 mg TEZ/75 mg IVA fixed dose combination----[1] 299
5100 mg VX-445 /50 mg TEZ/75 mg IVA FDC----[1] 299
6100 mg VX-445/50 mg TEZ /75 mg IVA FDC----[1] 299
7100-mg ELX (VX-445) / 50-mg TEZ / 75-mg IVA FDC----[1] 299
8100-mg ELX (VX-455) / 50-mg TEZ / 75-mg IVA FDC----[1] 299
9100-mg ELX / 50-mg TEZ / 75 -mg----[1] 299
10100-mg ELX / 50-mg TEZ / 75 -mg IVA FDC----[1] 299
11100-mg VX-445 / 50-mg TEZ / 75- mg IVA FDC----[1] 299
12100-mg VX-445 / 50-mg TEZ / 75-mg IVA FDC----[1] 299
13100-mg VX-445 /50-mg TEZ/75-mg----[1] 299
14100-mg VX-445/50-mg TEZ/75-mg IVA FDC----[1] 299
15100g ELX / 50mg TEZ / 75mg IVA----[1] 299
16100mg ELX/50mg TEZ /75mg IVA----[1] 299
17100mg VX-445/50mg TEZ /75mg IVA FDC----[1] 299
1856/104/75-C----[1] 50
1975----[1] 6
2075 mg Ontamalimab[1] Ontamalimab---[2] 96, 97
2175-mg IVACAFTOR[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
22750 mg metformin and 7.5 g L-citrulline daily p.o.[2] Citrulline,
Metformin (Synonym: Metformin ER 750 mg)		[3] D00944 ,
D04966 ,
D07706 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 113
23750mg mesalazine pellets[1] Mesalazine[1] D00377 --[1] 97
24755nm Alexandrite Laser----[1] 34
2575mg CXA-10[1] CXA-10---[1] 86
2675mg SHP647 (PF-00547659)----[1] 97
27AIN457, 75 mg----[1] 271
28Atacicept 75 mg[1] Atacicept[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[3] 13, 49, 66
29Atacicept 75 milligram (mg)[1] Atacicept[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
30AZLI 75 mg three times a day (TID)----[1] 299
31AZLI 75 mg three times daily (TID)----[1] 299
32AZLI 75 mg two times a day (BID)/ three times a day (TID)----[1] 299
33AZLI 75 mg two times a day (BID)/three times a day (TID)----[1] 299
34Betaloc ZOK 25, 23,75 mg----[1] 113
35BMS-986004 75 mg IV----[1] 63
36Bupivacaine
(Synonym: DURAPREN 0.75%)		[1] Bupivacaine[2] D01450 (Name: DURAPREN 0.75%),
D07552 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[8] 46, 51, 53, 70, 96, 168, 226, 298
37BUPIVACAINE HYDROCHLORIDE
(Synonym: DURAPREN 0.75%)		[1] Bupivacaine[2] D01450 (Name: DURAPREN 0.75%),
D07552 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[2] 46, 53
38Bupivacaine hydrochloride 0.5% (Marcaine, Pfizer)
(Synonym: DURAPREN 0.75%)		[1] Bupivacaine[2] D01450 (Name: DURAPREN 0.75%),
D07552 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 46
39Bupivacaine Injection 0.5%
(Synonym: DURAPREN 0.75%)		[1] Bupivacaine[2] D01450 (Name: DURAPREN 0.75%),
D07552 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 168
40Bupivacaine, triamcinolone, and heparin (BTH)
(Synonym: DURAPREN 0.75%)		[3] Bupivacaine,
Heparin,
Triamcinolone		[8] D00385 ,
D00983 ,
D00984 ,
D00985 ,
D01450 (Name: DURAPREN 0.75%),
D06216 ,
D07510 ,
D07552 		[7] NR3C1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SERPINC1 💬		[5] Adrenergic signaling in cardiomyocytes, Complement and coagulation cascades, Dopaminergic synapse, Neuroactive ligand-receptor interaction, Taste transduction 💬[1] 226
41Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine
(Synonym: DURAPREN 0.75%)		[3] Bupivacaine,
Clonidine,
Epinephrine		[7] D00095 ,
D00281 ,
D00604 ,
D00996 ,
D01450 (Name: DURAPREN 0.75%),
D02149 ,
D07552 		[14] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 70
42Bupivacaine/epinephrine/dexamethasone
(Synonym: DURAPREN 0.75%)		[3] Bupivacaine,
Dexamethasone,
Epinephrine		[14] D00095 ,
D00292 ,
D00975 ,
D00996 ,
D01450 (Name: DURAPREN 0.75%),
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02149 ,
D02174 ,
D02591 ,
D02592 ,
D07552 		[15] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3,
NR3C1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 96
43Catapresan 75----[1] 78
44Catapresan 75, Tabletten----[1] 65
45Cayston 75 mg Pulver und Lösungsmittel zur Herstellung einer Lösung für einen Vernebler[1] Aztreonam[2] D00240 ,
D06558 		--[1] 299
46CAYSTON aztreonam 75 mg powder and solvent for nebuliser solution[1] Aztreonam[2] D00240 ,
D06558 		--[1] 299
47Certican 0,75mg[1] Everolimus[1] D02714 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[1] 228
48Certican 0,75mg Tabletten[1] Everolimus[1] D02714 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[1] 228
49Cohort 2 0.75g----[1] 240
50Colistimethate 75 mg inhaled two times daily[1] Colistimethate[1] D02049 --[1] 299
51Comparator: diclofenac
(Synonym: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)		[1] Diclofenac (Synonym: NuDroxiPAK DSDR-75)[3] D00903 ,
D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
52Comparator: Diclofenac sodium
(Synonym: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)		[1] Diclofenac (Synonym: NuDroxiPAK DSDR-75)[3] D00903 ,
D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
53CVL-751----[1] 6
54Depot leuprolide acetate 3.75 mg[2] Acetate,
Leuprolide		[1] D00989 [1] GNRHR 💬[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 51
55Diclofenac
(Synonym: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)		[1] Diclofenac (Synonym: NuDroxiPAK DSDR-75)[3] D00903 ,
D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
56Diclofenac + Omeprazole
(Synonym: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)		[2] Diclofenac (Synonym: NuDroxiPAK DSDR-75),
Omeprazole		[7] D00455 ,
D00903 ,
D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK),
D01207 ,
D05259 ,
D05261 ,
D07816 		[4] ATP4A,
ATP4B,
PTGS1,
PTGS2 💬		[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Collecting duct acid secretion, Gastric acid secretion, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxidative phosphorylation, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
57Diclofenac 50 milligrams
(Synonym: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)		[1] Diclofenac (Synonym: NuDroxiPAK DSDR-75)[3] D00903 ,
D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 271
58Diclofenac Sodium
(Synonym: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)		[1] Diclofenac (Synonym: NuDroxiPAK DSDR-75)[3] D00903 ,
D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 34, 46
59Diclofenac sodium topical gel
(Synonym: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)		[1] Diclofenac (Synonym: NuDroxiPAK DSDR-75)[3] D00903 ,
D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 13
60Diclofenac SR
(Synonym: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)		[1] Diclofenac (Synonym: NuDroxiPAK DSDR-75)[3] D00903 ,
D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 271
61Dulaglutide 0.75Mg/0.5Ml Inj Pen[1] Dulaglutide[1] D09889 [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 299
62Ebetrex 15 mg = 0,75 ml, oplossing voor injectie in voorgevulde injectiespuit 20 mg/ml----[1] 96
63Efexor XL 75 mg----[1] 46
64Efexor XL 75 mg (venlafaxine)[1] Venlafaxine[2] D00821 ,
D08670 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 46
65ERCP with Bupivacaine infusion
(Synonym: DURAPREN 0.75%)		[1] Bupivacaine[2] D01450 (Name: DURAPREN 0.75%),
D07552 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 298
66IncobotulinumtoxinA (75 Units)[1] Botulinum toxin type A[1] D00783 [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 6
67Inhaled nitric oxide 75 mcg/kg IBW/hr[1] Nitric Oxide[1] D00074 --[2] 85, 86
68INM-755----[1] 36
69INM-755 (cannabinol) cream[1] Cannabinol---[1] 36
70Intravenous Infusion of Diclofenac Sodium
(Synonym: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK)		[1] Diclofenac (Synonym: NuDroxiPAK DSDR-75)[3] D00903 ,
D00904 (Name: DFS 75MG DR/MS 25%/MENTH 6%/CAP 0.025% PAK),
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 78
71Irbesartan tablets (NDA 020 757)[1] Irbesartan[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 66
72Ivacaftor 25 mg/75 mg[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
73Ivacaftor 75 mg[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
74Ivacaftor 75 mg/150 mg[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
75IVACAFTOR 75mg[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
76Jaktinib Dihydrochloride Monohydrate 50mg BID and Mimic tablets of jakitinib hydrochloride 75mg BID and Acetylcysteine Effervescent Tablets[1] Acetylcysteine[1] D00221 --[1] 85
77Jaktinib Dihydrochloride Monohydrate 75mg BID and Mimic tablets of jakitinib hydrochloride 50mg BID and Acetylcysteine Effervescent Tablets[1] Acetylcysteine[1] D00221 --[1] 85
78JNJ-54781532 75 mg once daily----[1] 97
79JNJ-54781532 75 mg twice daily----[1] 97
80Lap TAP Bupivacaine/Epinephrine
(Synonym: DURAPREN 0.75%)		[2] Bupivacaine,
Epinephrine		[5] D00095 ,
D00996 ,
D01450 (Name: DURAPREN 0.75%),
D02149 ,
D07552 		[14] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 96
81Leuprorelin Acetate 3.75mg Injection[2] Acetate,
Leuprolide		[1] D00989 [1] GNRHR 💬[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 76
82Levodopa 75 mg A CAP[1] Levodopa[1] D00059 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
83Liposomal bupivacaine
(Synonym: DURAPREN 0.75%)		[1] Bupivacaine[2] D01450 (Name: DURAPREN 0.75%),
D07552 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 51, 70, 96
84LIQ861 75 µg----[1] 86
85Luphere depot 3.75mg(Leuprolide acetate 3.75mg)[2] Acetate,
Leuprolide		[1] D00989 [1] GNRHR 💬[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 76
86M2951 75 mg QD----[1] 46
87Macitentan 75 mg[1] Macitentan[1] D10135 [2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
88MetoHEXAL® Succ ® 23,75 mg Retardtabletten----[1] 113
89Oral Glucose Tolerance test (75g 2-hour)[1] Dextrose, unspecified form (Synonym: Glucotol Liq 75gm/300ml Cola 75)---[1] 299
90Other: glucose solution at a dose of 1.75 g/kg (up to a maximum of 75 g) for the OGTT and glucose solution at a dose of 0.5 g/kg (up to a maximum of 35 g) was injected in 2.5-3 min for the IGTT[1] Dextrose, unspecified form (Synonym: Glucotol Liq 75gm/300ml Cola 75)---[1] 299
91Over-encapsulated 75 mg Irbesartan Tablets[1] Irbesartan[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222
92P2B001 once daily (pramipexole 0.3 mg / rasagiline 0.75 mg),[2] Pramipexole,
Rasagiline		[5] D00559 ,
D02562 ,
D05575 ,
D08469 ,
D10829 		[4] DRD2,
DRD3,
DRD4,
MAOB 💬		[18] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
93P2B001 once daily (pramipexole 0.6 mg / rasagiline 0.75 mg),[2] Pramipexole,
Rasagiline		[5] D00559 ,
D02562 ,
D05575 ,
D08469 ,
D10829 		[4] DRD2,
DRD3,
DRD4,
MAOB 💬		[18] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
94P38 Inhibitor (4) 75mg----[1] 46
95Pregabalin 75mg[1] Pregabalin (Synonym: Pregabalin-75)[1] D02716 [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[1] 70
96RANEXA - 750 MG - COMPRESSA A RILASCIO PROLUNGATO- USO ORALE - BLISTER (PVC/PVDC/ALLUMINIO) 60 COMPRESSE[1] Ranolazine[2] D05700 ,
D05701 		--[1] 58
97RANEXA*60CPR 750MG R.P.[1] Ranolazine[2] D05700 ,
D05701 		--[1] 58
98Ranolazine 750 mg PR tablets[1] Ranolazine[2] D05700 ,
D05701 		--[1] 58
99Ranolazine PR (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die[1] Ranolazine[2] D05700 ,
D05701 		--[1] 58
100Revolade 75 mg[1] Eltrombopag---[1] 60
101RhuDex 25 mg (31.75 mg RhuDex choline salt) granules[1] Choline (Synonym: Mega-vim 75 With Beta-carotene - Tablets)[1] D07690 --[1] 93
102RO 487-7533----[1] 46
103Ro 487-7533/F01----[3] 46, 107, 271
104Ro 487-7533/F10----[2] 46, 107
105Ro 487-7533/F10-02----[1] 46
106Ro 487-7533/F10-04----[4] 41, 46, 51, 107
107Ro 491-7523/F18----[1] 206
108Ro 491-7523/F19----[1] 206
109Ro487-7533----[1] 46
110RO487-7533/F01-F05----[1] 46
111RO487-7533/F10-04----[2] 46, 51
112Secukinumab (75 mg)[1] Secukinumab[1] D09967 [1] IL17A 💬[6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[1] 271
113Secukinumab 75 mg/0.5 ml Solution for injection[1] Secukinumab[1] D09967 [1] IL17A 💬[6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[1] 271
114SUSPENSION CONTAINING 7500 EMBRYONATED VIABLE TRICHURIS SUIS OVA/15ML----[1] 97
115Suspension containing 7500 embryonated, viable Trichuris suis ova (TSO)/15ml----[1] 96
116Suspension of 7500 embryonated, viable TSO/15ml----[1] 96
117TAK-755----[1] 64
118TAK-755 or BAX930 or SHP655----[1] 64
119TAK-755 orBAX930 or SHP655----[1] 64
120Trulicity 0,75 mg injekcný roztok naplnený v injekcnom pere[1] Dulaglutide[1] D09889 [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 13
121Trulicity 0,75 mg injekcný roztok naplnený v injekcnom pere.[1] Dulaglutide[1] D09889 [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 13
122TSO 7500----[1] 96
123US TAP Bupivacaine/Epinephrine
(Synonym: DURAPREN 0.75%)		[2] Bupivacaine,
Epinephrine		[5] D00095 ,
D00996 ,
D01450 (Name: DURAPREN 0.75%),
D02149 ,
D07552 		[14] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 96
124Vamorolone 0.75 mg/day/day[1] Vamorolone[1] D11000 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 113
125Vamorolone 0.75 mg/kg/day[1] Vamorolone[1] D11000 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 113
126Veltuzumab solution 75mg/ml[1] Veltuzumab[1] D09031 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 46
127VX-661/ivacaftor 50 mg/ 75 mg[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
128XYOSTED 75 milligram (mg) in 0.5 ML Auto-Injector[1] Testosterone enanthate[1] D00958 [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 13