Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
12-(4-[5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy)-N-(methylsulfonyl)actamide----[1] 86
290 mg hydrocortisone acetate suppository with Sephure suppository applicator
(Synonym: Acticort (TN))		[3] Acetate,
Hydrocortisone,
Hydrocortisone acetate (Synonym: Actinac Pws)		[2] D00088 (Name: Acticort (TN)),
D00165 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
3A novel synthetic, orally-administered, non-peptide small molecule, which acts as----[1] 254
4A novel synthetic, orally-administered, non-peptide small molecule, which acts as an agonist of the melanocortin-1 receptor (MC1R)----[1] 51
5A-dopamine
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
6Abatacept Active Treatment[1] Abatacept[1] D03203 [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[1] 50
7Abatacept, rituximab or tocilizumab
(Synonym: Actemra (TN))		[3] Abatacept,
Rituximab,
Tocilizumab (Synonym: Actemra ACTPen)		[3] D02596 (Name: Actemra (TN)),
D02994 ,
D03203 		[4] CD80,
CD86,
IL6R,
MS4A1 💬		[24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
8ACT----[1] 13
9ACT - 064992----[1] 86
10ACT-050089----[1] 86
11ACT-050089 (Ro 61-0612)----[1] 86
12ACT-064992----[5] 51, 85, 86, 88, 210
13ACT-064992 (macitentan)[1] Macitentan[1] D10135 [2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
14ACT-064992 / JNJ-67896062----[1] 86
15ACT-064992/ JNJ-67896062----[1] 86
16ACT-064992D----[1] 86
17ACT-1----[1] 13
18ACT-128800----[1] 13
19ACT-128800 Dose 1----[1] 13
20ACT-128800 Dose 2----[1] 13
21ACT-128800 Dose 3----[1] 13
22ACT-178418----[1] 86
23ACT-293987----[3] 51, 86, 88
24ACT-293987 (NS-304)----[1] 86
25ACT-293987 / JNJ-67896049----[1] 84
26ACT-334441----[1] 49
27ACT-385781A----[1] 86
28ACT-385781A (Actelion Epoprostenol)[1] Epoprostenol[2] D00106 ,
D01337 		[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
29ACT-434964----[1] 19
30Act-HiB[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen (Synonym: ActHIB)---[4] 14, 61, 62, 222
31ACT-HIB Polvere e solvente per soluzione iniettabile in siringa preriempita 0,5 ml[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen (Synonym: ActHIB)---[2] 61, 62
32Actemra[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
33Actemra(EU-licensed)[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
34Actemra, MRA[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 107
35Acteoside[1] Acteoside---[1] 66
36ACTH[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 13, 66, 145, 193, 222
37ACTH (Acthar) Gel[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 66
38Acthar[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[9] 2, 13, 14, 46, 49, 50, 66, 84, 222
39Acthar 80 unit injection[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 66
40Acthar Gel[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 13, 46, 49, 50, 84, 222
41ACTHAR Gel (ACTH)[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 13
42ACTHAR Gel (adrenocorticotropic hormone)[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 84
43ACTHAR Gel 40 units twice weekly[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 84
44ACTHAR Gel 80 units twice weekly.[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 84
45Acthar high dose (80 U)[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 49
46Acthar Injectable Product[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 46
47Acthar low dose (40 U)[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 49
48ActHIB[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen (Synonym: ActHIB)---[2] 62, 66
49ACTHIB - POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE 1 FLACONCINO POLVERE+1 SIRINGA PRERIEMPITA SOLVENTE 0.5 ML[1] Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen (Synonym: ActHIB)---[2] 62, 66
50Acthrel[1] Corticorelin ovine triflutate (Synonym: Ovine ACTH releasing factor)[1] D03592 (Name: Acthrel (TN))[2] CRHR1,
CRHR2 💬		[4] Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 75
51ACTIMMUNE[1] Interferon gamma-1b (Synonym: Actimmune)[1] D00747 (Name: Actimmune (TN))[2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[1] 326
52Actimmune Registry[1] Interferon gamma-1b (Synonym: Actimmune)[1] D00747 (Name: Actimmune (TN))[2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[1] 326
53ActiMyo recording----[1] 6
54Activated smart device----[1] 299
55Active BMN 111: Daily subcutaneous injection of 15 ug/kg of BMN 111----[1] 276
56Active comparator----[2] 6, 46
57Active Comparator receiving Extavia®[1] Interferon beta-1b[1] D00746 [2] IFNAR1,
IFNAR2 💬		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 13
58Active Control----[1] 13
59Active drug (BIIB014) at 10, 30, 100, or 300 mg once daily.----[1] 6
60Active drug: pimavanserin 17mg (2 strength tablets)[1] Pimavanserin---[1] 6
61Active Investigational Treatment ENT-01----[1] 6
62Active Stimulation----[1] 46
63Active tDCS----[1] 6
64Active topical NS2 1% dermatologic cream----[1] 160
65Active tPCS----[1] 6
66Active Treatment Group 7% Hypertonic Saline----[1] 299
67Activity Monitor[1] Methamidophos---[1] 113
68Actonel 5mg Film Coated Tablets[1] Risedronic acid (Synonym: Actonel Sachet Kit)[3] D00942 (Name: Actonel (TN)),
D03234 (Name: Actonel (TN)),
D08484 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
69Actonel Once a Week 35 mg film-coated tablets[1] Risedronic acid (Synonym: Actonel Sachet Kit)[3] D00942 (Name: Actonel (TN)),
D03234 (Name: Actonel (TN)),
D08484 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
70Actonel Once a week 5mg film coated tablets[1] Risedronic acid (Synonym: Actonel Sachet Kit)[3] D00942 (Name: Actonel (TN)),
D03234 (Name: Actonel (TN)),
D08484 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 113
71Actonel/Optinate 5mg film-coated tablets[1] Risedronic acid (Synonym: Actonel Sachet Kit)[3] D00942 (Name: Actonel (TN)),
D03234 (Name: Actonel (TN)),
D08484 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
72ACTOS (Pioglitazone)[1] Pioglitazone (Synonym: Actoplus Met)[2] D00945 (Name: Actos (TN)),
D08378 (Name: Actos (TN))		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 13
73Actos 15 mg[1] Pioglitazone (Synonym: Actoplus Met)[2] D00945 (Name: Actos (TN)),
D08378 (Name: Actos (TN))		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 2
74Actos 30 mg[1] Pioglitazone (Synonym: Actoplus Met)[2] D00945 (Name: Actos (TN)),
D08378 (Name: Actos (TN))		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 2
75Actos 45 mg[1] Pioglitazone (Synonym: Actoplus Met)[2] D00945 (Name: Actos (TN)),
D08378 (Name: Actos (TN))		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 2
76Actrapid 100 IU/ml, Solution for injection in a vial----[1] 299
77Actrapid Penfill 100UI/ml----[1] 299
78ActRIIA-IgG1Fc----[1] 86
79Adalimuab, Etanercept, Tocilizumab, or Abatacept
(Synonym: Actemra (TN))		[3] Abatacept,
Etanercept,
Tocilizumab (Synonym: Actemra ACTPen)		[3] D00742 ,
D02596 (Name: Actemra (TN)),
D03203 		[5] CD80,
CD86,
IL6R,
LTA,
TNF 💬		[79] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cell adhesion molecules, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
80Adempas (active agent riociguat)[1] Riociguat[1] D09572 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 86, 88
81Adjuvant without active component----[2] 6, 17
82Adrenocorticotrophic hormone ACTH[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 222
83Adrenocorticotropic hormone (ACTH) gel (H.P. Acthar®)[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 13
84Amoxicillin, metronidazole and doxycycline
(Synonym: ACTICLATE)		[3] Amoxicillin,
Doxycycline (Synonym: Acticlate),
Metronidazole		[11] D00229 ,
D00307 ,
D00409 ,
D02129 (Name: ACTICLATE),
D02925 ,
D03903 ,
D03904 ,
D05016 ,
D05017 ,
D07452 ,
D07876 		--[1] 97
85Anti BAFF (B cell activating factor)----[1] 49
86Antimicrobial therapy: Co-trimoxazole or Doxycycline
(Synonym: ACTICLATE)		[1] Doxycycline (Synonym: Acticlate)[5] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D07876 		--[1] 85
87Anxiety/depression and work and activities----[1] 13
88Behavioral: BCI-FIT active querying----[3] 2, 6, 17
89Behavioral: Physical Activity Together for PwMS and their CGs (PAT-MS)----[1] 13
90Behavioral: Role of dopamine
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
91Behavioral: Sleep quality and physical activity----[1] 13
92Biologically active human fecal microbiota----[1] 97
93Bromocriptine and other dopamine agonists
(Synonym: Actopamin (TN))		[2] Bromocriptine,
Dopamine		[4] D00633 (Name: Actopamin (TN)),
D00780 ,
D03165 ,
D07870 		[6] DRD1,
DRD2,
DRD3,
DRD4,
DRD5,
PRL 💬		[15] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
94BT-11 Active----[2] 96, 97
95Cerebral Dopamine Neurotrophic Factor
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
96CFZ533 active - Cohort 1----[1] 53
97CFZ533 active - Cohort 2----[1] 53
98CFZ533 active - Cohort 3----[1] 53
99CFZ533 active -Cohort 3----[1] 53
100CJNJ-68150420-ZZZ-G001 (ACT- 064992D)----[1] 86
101CJNJ-68150420-ZZZ-G001 (ACT-064992D)----[1] 86
102CJNJ-68150420-ZZZ-G001(ACT-064992D)----[1] 86
103Combination Oral Budesonide and Rectal Hydrocortisone
(Synonym: Acticort (TN))		[2] Budesonide,
Hydrocortisone		[2] D00088 (Name: Acticort (TN)),
D00246 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
104Combination Product: Active treatment with dual therapy----[1] 2
105Combination Product: Twice daily 90 mg hydrocortisone acetate suppository administered with Sephure applicator
(Synonym: Acticort (TN))		[2] Acetate,
Hydrocortisone		[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
106Continuous Release Dopamine Agonists
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
107Conventional Glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone)
(Synonym: Acticort (TN))		[6] Acetate,
Cortisone acetate,
Dexamethasone,
Hydrocortisone,
Prednisolone,
Prednisone		[20] D00088 (Name: Acticort (TN)),
D00292 ,
D00472 ,
D00473 ,
D00973 ,
D00975 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D01998 ,
D02156 ,
D02174 ,
D02591 ,
D02592 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
108Cortef (hydrocortisone)
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 83
109Corticoids+ tocilizumab 8mg/Kg/4 weeks
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
110Corticotropin
(Synonym: ACTH (TN))		[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[9] 2, 13, 46, 75, 78, 81, 84, 205, 222
111Corticotropin-releasing hormone
(Synonym: ACTH (TN))		[2] Corticorelin,
Corticotropin (Synonym: Acthar)		[2] D00146 (Name: ACTH (TN)),
D03905 		[3] CRHR1,
CRHR2,
MC2R 💬		[6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[2] 75, 205
112Crinecerfont is a novel non-peptide selective corticotropin releasing factor 1 (CRF1 ) receptor antagonist.
(Synonym: ACTH (TN))		[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 81
113De-activated smart device----[1] 299
114Decrease Tocilizumab, Abatacept
(Synonym: Actemra (TN))		[2] Abatacept,
Tocilizumab (Synonym: Actemra ACTPen)		[2] D02596 (Name: Actemra (TN)),
D03203 		[3] CD80,
CD86,
IL6R 💬		[24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
115Diagnostic Test: Disease activity----[1] 46
116Diagnostic Test: DM1-ActivC----[1] 113
117Diagnostic Test: fibrinogen plasma concentration, coagulation factor XIII activity[2] Factor XIII (human),
Fibrinogen human		---[1] 288
118Diagnostic Test: Plasma a-Gal A activity----[1] 19
119Diagnostic Test: The Juvenile Disease Activity Score (JADAS)----[1] 107
120Dopamine
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 7, 74
121Dopamine Agent
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
122Dopamine agonist treatment
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 74
123Dopamine Agonists
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 74
124Dopamine Agonists (pramipexole, ropirinole)
(Synonym: Actopamin (TN))		[2] Dopamine,
Pramipexole (Synonym: Act Pramipexole)		[4] D00559 ,
D00633 (Name: Actopamin (TN)),
D05575 ,
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
125Doxycycline
(Synonym: ACTICLATE)		[1] Doxycycline (Synonym: Acticlate)[5] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D07876 		--[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
126Doxycycline 100 mg Capsules
(Synonym: ACTICLATE)		[1] Doxycycline (Synonym: Acticlate)[5] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D07876 		--[1] 89
127Doxycycline 100-200mg capsules daily for 6 months
(Synonym: ACTICLATE)		[1] Doxycycline (Synonym: Acticlate)[5] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D07876 		--[1] 167
128DOXYCYCLINE HYCLATE
(Synonym: ACTICLATE)		[1] Doxycycline (Synonym: Acticlate)[5] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D07876 		--[3] 23, 96, 227
129Doxycycline Hyclate Ph.Eur
(Synonym: ACTICLATE)		[1] Doxycycline (Synonym: Acticlate)[5] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D07876 		--[1] 167
130Doxycycline Tablets
(Synonym: ACTICLATE)		[1] Doxycycline (Synonym: Acticlate)[5] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D07876 		--[1] 46
131Dual release hydrocortisone (plenadren)
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
132EFI/ACT-385781A----[1] 86
133Embryonic dopamine cell implant surgery
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
134Epoprostenol-Actelion[1] Epoprostenol[2] D00106 ,
D01337 		[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
135Etanercepet, Rituximab, Abatacept, Tocilizumab, Sarilumab
(Synonym: Actemra (TN))		[4] Abatacept,
Rituximab,
Sarilumab,
Tocilizumab (Synonym: Actemra ACTPen)		[4] D02596 (Name: Actemra (TN)),
D02994 ,
D03203 ,
D10161 		[4] CD80,
CD86,
IL6R,
MS4A1 💬		[24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
136Fentanyl
(Synonym: ACTIQ)		[1] Fentanyl (Synonym: Actiq)[2] D00320 ,
D01399 (Name: ACTIQ)		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[4] 46, 70, 215, 231
137Fentanyl (High Dose)
(Synonym: ACTIQ)		[1] Fentanyl (Synonym: Actiq)[2] D00320 ,
D01399 (Name: ACTIQ)		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 215
138Fentanyl (Low Dose)
(Synonym: ACTIQ)		[1] Fentanyl (Synonym: Actiq)[2] D00320 ,
D01399 (Name: ACTIQ)		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 215
139Fentanyl (Low Dose) + Dexmedetomidine
(Synonym: ACTIQ)		[2] Dexmedetomidine,
Fentanyl (Synonym: Actiq)		[4] D00320 ,
D00514 ,
D01205 ,
D01399 (Name: ACTIQ)		[4] ADRA2A,
ADRA2B,
ADRA2C,
OPRM1 💬		[4] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 215
140Fentanyl transdermal patch
(Synonym: ACTIQ)		[1] Fentanyl (Synonym: Actiq)[2] D00320 ,
D01399 (Name: ACTIQ)		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 46
141Gene Activated a-Galactosidase A----[1] 19
142Gene Activated Human Glucocerebrosidase----[1] 19
143Gene activated human glucocerebrosidase, velaglucerase alfa[1] Velaglucerase alfa[1] D09029 [1] GBA 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
144Gene-Activated Human Glucocerebrosidase----[1] 19
145Gene-Activated Human Glucocerebrosidase 200U/vial----[1] 19
146Gene-Activated Human Glucocerebrosidase 400U/vial----[1] 19
147Genetic: Genetic test: ACTN3 polymorphism----[3] 3, 15, 256
148H.P. Acthar Gel[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 46, 49, 50, 84, 222
149H.P. Acthar Gel (repository corticotropin injection)[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 13
150H.P. Acthar® Gel[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 14
151HrIL-2 active----[3] 46, 49, 53
152Hydrocortisone
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
153Hydrocortisone (Solucortef)
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
154Hydrocortisone 100mg/ml
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 83
155Hydrocortisone 10mg
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 46
156Hydrocortisone 10mg Tablet
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
157Hydrocortisone 10mg Tablets
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
158Hydrocortisone 20mg Tablets
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
159HYDROCORTISONE ACETATE
(Synonym: Acticort (TN))		[2] Acetate,
Hydrocortisone		[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
160Hydrocortisone cream
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 6
161Hydrocortisone cream 1%
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 6
162Hydrocortisone cream 10mg/g FNA Fagron
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 6
163HYDROCORTISONE HYDROGEN SUCCINATE
(Synonym: Acticort (TN))		[3] Hydrocortisone,
Hydrocortisone succinate,
Hydrogen		[2] D00088 (Name: Acticort (TN)),
D01442 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 83
164HYDROCORTISONE MICRONIZED
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
165Hydrocortisone Modified Release Capsules
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
166HYDROCORTISONE ROUSSEL
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 83
167Hydrocortisone sodium acetate
(Synonym: Acticort (TN))		[3] Acetate,
Hydrocortisone,
Sodium acetate		[2] D00088 (Name: Acticort (TN)),
D01779 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
168HYDROCORTISONE SODIUM PHOSPHATE
(Synonym: Acticort (TN))		[2] Hydrocortisone,
Phosphate ion		[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 53, 81, 83
169HYDROCORTISONE SODIUM SUCCINATE
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 81, 83, 97
170Hydrocortisone tablet 2.5 mg
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
171Hydrocortisone TAKEDA, tabletter
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 78
172Hydrocortisone withdrawal
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
173HYDROCORTISONE- hydrocortisone tablet
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
174INN-Tocilizumab
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 266
175Interferon beta 1a, oral doxycycline
(Synonym: ACTICLATE)		[3] Doxycycline (Synonym: Acticlate),
Human interferon beta,
Interferon beta-1a		[6] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D04554 ,
D07876 		[2] IFNAR1,
IFNAR2 💬		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 13
176INTERFERON GAMMA-1B
(Synonym: Actimmune (TN))		[2] Interferon Gamma,
Interferon gamma-1b (Synonym: Actimmune)		[1] D00747 (Name: Actimmune (TN))[2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326
177Interferon gamma-1b (Actimmune)[2] Interferon Gamma,
Interferon gamma-1b (Synonym: Actimmune)		[1] D00747 (Name: Actimmune (TN))[2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[1] 85
178Intra-articular Tocilizumab
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
179JNJ-67896049 (ACT-293987)----[1] 86
180JNJ-67896062 / ACT-064992----[2] 86, 88
181JNJ-67896062/ ACT-064992----[2] 86, 88
182Lamotrigin actavis----[1] 114
183Long-Acting Growth Hormone (LAGH)[1] Somatotropin[1] D02691 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
184Long-acting somatostatin[1] Somatostatin[1] D07431 [5] SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬		[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 67
185Macitentan (ACT-064992)[1] Macitentan[1] D10135 [2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
186Mesalazine with hydrocortisone sodium succinate
(Synonym: Acticort (TN))		[2] Hydrocortisone,
Mesalazine		[2] D00088 (Name: Acticort (TN)),
D00377 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
187MRA (Actemra)[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 107
188MRA (Tocilizumab)
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
189MRA(Tocilizumab)
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
190MRA, Actemra[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
191Multi-modal pain management [Fentanyl]
(Synonym: ACTIQ)		[1] Fentanyl (Synonym: Actiq)[2] D00320 ,
D01399 (Name: ACTIQ)		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 70
192Nanocrystalline silver (Acticoat)[1] Silver (Synonym: Argentyn 23Bio active silver Bio active silver hydrosol)---[2] 35, 162
193Non-active stimulation----[1] 46
194Novorapid / humalog short acting insulin----[1] 299
195Octreotide LAR / Sandostatin LAR (LAR=long acting release)[1] Octreotide[2] D00442 ,
D06495 		[1] SSTR2 💬[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 84
196Omnidirectional accelerometer monitor (3x3 cm and 16 g, Actical®, Philips Respironics)[1] Methamidophos---[1] 118
197Other: corticotropin releasing hormone (CRH)
(Synonym: ACTH (TN))		[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 78
198Other: Fitbit Activity Monitor[1] Methamidophos---[1] 49
199Other: Hydrocortisone
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 75
200Other: Low dose (1 mcg) ACTH stimulation test[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 193
201Other: No active treatment----[1] 274
202Other: No doxycycline
(Synonym: ACTICLATE)		[1] Doxycycline (Synonym: Acticlate)[5] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D07876 		--[1] 299
203Other: Noninvasive actigraphy monitor[1] Methamidophos---[1] 86
204Other: Tampa Kinesiophobia Scale, Berg-Balance Test, International Physical Activity Questionnaire-Short Form, Falls Efficacy Scale[1] Isoxaflutole---[1] 6
205Ovine Corticotropin-Releasing Hormone (oCRH)
(Synonym: ACTH (TN))		[2] Corticorelin,
Corticotropin (Synonym: Acthar)		[2] D00146 (Name: ACTH (TN)),
D03905 		[3] CRHR1,
CRHR2,
MC2R 💬		[6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 75
206Pioglitazone
(Synonym: Actos (TN))		[1] Pioglitazone (Synonym: Actoplus Met)[2] D00945 (Name: Actos (TN)),
D08378 (Name: Actos (TN))		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
207Pioglitazone 15 mg
(Synonym: Actos (TN))		[1] Pioglitazone (Synonym: Actoplus Met)[2] D00945 (Name: Actos (TN)),
D08378 (Name: Actos (TN))		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 96
208Pioglitazone and Tretinoin
(Synonym: Actos (TN))		[2] Pioglitazone (Synonym: Actoplus Met),
Tretinoin		[3] D00094 ,
D00945 (Name: Actos (TN)),
D08378 (Name: Actos (TN))		[4] PML,
PPARG,
RARA,
RARB 💬		[21] AMPK signaling pathway, Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Huntington disease, Influenza A, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[1] 2
209Pioglitazone or metformin
(Synonym: Actos (TN))		[2] Metformin (Synonym: Act Metformin),
Pioglitazone (Synonym: Actoplus Met)		[4] D00944 ,
D00945 (Name: Actos (TN)),
D04966 ,
D08378 (Name: Actos (TN))		[3] PPARG,
PRKAA1,
PRKAA2 💬		[27] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Huntington disease, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Osteoclast differentiation, Oxytocin signaling pathway, PI3K-Akt signaling pathway, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Tight junction, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[1] 265
210Recombinant human Cerebral Dopamine Neurotrophic Factor
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
211Reh-acteoside[1] Acteoside---[1] 66
212Repository corticotropin injection
(Synonym: ACTH (TN))		[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 2, 13, 46, 84, 222
213Repository Corticotropin Injection -Treatment Extension
(Synonym: ACTH (TN))		[1] Corticotropin (Synonym: Acthar)[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 84
214Risedronate sodium (Actonel)[1] Risedronic acid (Synonym: Actonel Sachet Kit)[3] D00942 (Name: Actonel (TN)),
D03234 (Name: Actonel (TN)),
D08484 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
215Risedronic acid
(Synonym: Actonel (TN))		[1] Risedronic acid (Synonym: Actonel Sachet Kit)[3] D00942 (Name: Actonel (TN)),
D03234 (Name: Actonel (TN)),
D08484 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 93, 95, 274
216Rituximab, observational study amon patients with active RA[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 46
217Ro 47-0203 / ACT-050088----[1] 86
218Ro Actemra[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
219Ro-Actemra[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
220Ro47-0203 / ACT-050088----[2] 51, 86
221RoActemra/Actemra (tocilizumab)[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 107
222Selexipag, ACT-293987 (NS-304)[1] Selexipag[1] D09994 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
223Short-acting Insulin (Actrapid)----[1] 299
224Solu-Cortef (hydrocortisone)
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 83
225Solu-Cortef, powder for solution for injection, 100mg, and 'Act-O-Vial'[2] Hydrocortisone,
Hydrocortisone succinate		[2] D00088 (Name: Acticort (TN)),
D01442 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 6
226Solution de chlorhydrate de dopamine anaérobie
(Synonym: Actopamin (TN))		[1] Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
227Standard analgesia use [Fentanyl]
(Synonym: ACTIQ)		[1] Fentanyl (Synonym: Actiq)[2] D00320 ,
D01399 (Name: ACTIQ)		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 70
228Subcutaneous hydrocortisone
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
229Subcutaneous hydrocortisone 10mg
(Synonym: Acticort (TN))		[1] Hydrocortisone[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 6
230Subcutaneous tocilizumab
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
231Subcutaneous tocilizumab 162mg/biweekly
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
232Time and attention + active fructooligosaccharide supplementation----[1] 96
233Tocilizumab
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
234Tocilizumab (Actemra or RoActemra)[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
235Tocilizumab (Actemra)[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
236Tocilizumab (Actemra®)[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
237Tocilizumab (MRA-SC)
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 40
238Tocilizumab (TCZ)
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 56
239Tocilizumab + Glucocorticoids (GCs)
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
240Tocilizumab + methotrexate(MTX)
(Synonym: Actemra (TN))		[2] Methotrexate,
Tocilizumab (Synonym: Actemra ACTPen)		[3] D00142 ,
D02115 ,
D02596 (Name: Actemra (TN))		[3] DHFR,
DHFR2,
IL6R 💬		[17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
241Tocilizumab 162 mg
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
242Tocilizumab 162mg/0.9ml jeringa SC
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
243Tocilizumab 162mg/0.9ml SC PFS SC
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
244Tocilizumab 162mg/0.9ml syringe SC
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
245Tocilizumab [RoActemra/Actemra][1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[4] 46, 51, 107, 331
246Tocilizumab [RoActemra]
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
247Tocilizumab and IV steroids combination
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
248Tocilizumab Infusion RoAcemtra (EU)
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 266
249Tocilizumab Injectable Product
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 11
250Tocilizumab Injection
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 13
251Tocilizumab Injection 8mg/kg
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
252Tocilizumab IV
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
253Tocilizumab plus methotrexate
(Synonym: Actemra (TN))		[2] Methotrexate,
Tocilizumab (Synonym: Actemra ACTPen)		[3] D00142 ,
D02115 ,
D02596 (Name: Actemra (TN))		[3] DHFR,
DHFR2,
IL6R 💬		[17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
254Tocilizumab Prefilled Syringe
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 41, 46
255Tocilizumab Roche
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
256TOCILIZUMAB SC
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[3] 41, 46, 107
257Tocilizumab SC 162 mg/0.9 ml disposable auto-injector (AI)
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
258Tocilizumab SC 162 mg/0.9 ml pre-filled syringe with safety device (PFS)
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
259Tocilizumab SC 162 mg/0.9 ml prefilled syringe with safety device (PFS)
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 51
260Tocilizumab treatment
(Synonym: Actemra (TN))		[1] Tocilizumab (Synonym: Actemra ACTPen)[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
261Tocilizumab+Methotrexate(MTX)
(Synonym: Actemra (TN))		[2] Methotrexate,
Tocilizumab (Synonym: Actemra ACTPen)		[3] D00142 ,
D02115 ,
D02596 (Name: Actemra (TN))		[3] DHFR,
DHFR2,
IL6R 💬		[17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
262Tocilizumab, Abatacept
(Synonym: Actemra (TN))		[2] Abatacept,
Tocilizumab (Synonym: Actemra ACTPen)		[2] D02596 (Name: Actemra (TN)),
D03203 		[3] CD80,
CD86,
IL6R 💬		[24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
263Transdermal fentanyl matrix, gabapentin
(Synonym: ACTIQ)		[2] Fentanyl (Synonym: Actiq),
Gabapentin (Synonym: ACTIVE-PAC with Gabapentin)		[3] D00320 ,
D00332 ,
D01399 (Name: ACTIQ)		[6] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
OPRM1,
SLC6A1 💬		[12] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Estrogen signaling pathway, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[1] 70
264Treatment defined only by active substance----[1] 50
265Treatment with systemic therapy (doxycycline)
(Synonym: ACTICLATE)		[1] Doxycycline (Synonym: Acticlate)[5] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D07876 		--[1] 162
266Tretinoin and Pioglitazone HCL
(Synonym: Actos (TN))		[2] Pioglitazone (Synonym: Actoplus Met),
Tretinoin		[3] D00094 ,
D00945 (Name: Actos (TN)),
D08378 (Name: Actos (TN))		[4] PML,
PPARG,
RARA,
RARB 💬		[21] AMPK signaling pathway, Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Huntington disease, Influenza A, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[1] 2
267UDCA (Ursodeoxycholic acid)
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[1] 93
268Ursodeoxycholic acid
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[9] 6, 46, 67, 84, 93, 94, 95, 96, 97
269Ursodeoxycholic acid (UDCA)
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[1] 94
270Ursodeoxycholic acid (UDCA) 500 mg
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[1] 46
271Ursodeoxycholic Acid (URSO)
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[1] 93
272Ursodeoxycholic Acid 300mg capsule
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[1] 93
273Ursodeoxycholic Acid 300mg tablet
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[1] 93
274Ursodeoxycholic Acid Capsules
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[1] 93
275Ursodeoxycholic acid combination of immunosuppressive agents
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[2] 93, 95
276Ursodeoxycholic acid combined with total glucosides of paeony
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[1] 93
277Ursodeoxycholic acid only
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[1] 93
278Ursodeoxycholic acid+Low Dose Glucocorticoid(Methylprednisolone)
(Synonym: Actigall (TN))		[2] Methylprednisolone,
Ursodeoxycholic acid (Synonym: Actigall)		[7] D00407 ,
D00734 (Name: Actigall (TN)),
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[2] NR1H4,
NR3C1 💬		[2] Bile secretion, Neuroactive ligand-receptor interaction 💬[1] 93
279Ursodiol (ursodeoxycholic acid, UDCA)
(Synonym: Actigall (TN))		[1] Ursodeoxycholic acid (Synonym: Actigall)[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[1] 97
280UTTR1147A/RO7021610 (Active)----[2] 96, 97
281Wristband physical activity monitor[1] Methamidophos---[1] 13