Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Dextromethorphan
(Synonym: Dextromethorphan hydrobromide)		[1] Dextromethorphan (Synonym: Guaifenesin and Dextromethorphan Hydrobromide)[3] D00848 (Name: Dextromethorphan hydrobromide),
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2Dextromethorphan 30 mg
(Synonym: Dextromethorphan hydrobromide)		[1] Dextromethorphan (Synonym: Guaifenesin and Dextromethorphan Hydrobromide)[3] D00848 (Name: Dextromethorphan hydrobromide),
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 96, 97
3Dextromethorphan and Caffeine
(Synonym: Dextromethorphan hydrobromide)		[2] Caffeine,
Dextromethorphan (Synonym: Guaifenesin and Dextromethorphan Hydrobromide)		[5] D00528 ,
D00848 (Name: Dextromethorphan hydrobromide),
D01453 ,
D03742 ,
D03744 		[17] ADORA1,
ADORA2A,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A,
SIGMAR1 💬		[37] Alcoholism, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Huntington disease, Insulin signaling pathway, Long-term potentiation, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 78
4Dextromethorphan HBr and quinidine sulfate
(Synonym: Dextromethorphan hydrobromide)		[3] Dextromethorphan (Synonym: Guaifenesin and Dextromethorphan Hydrobromide),
Quinidine,
Sulfate ion		[7] D00642 ,
D00643 ,
D00848 (Name: Dextromethorphan hydrobromide),
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[1] 2
5DEXTROMETHORPHAN HYDROBROMIDE[1] Dextromethorphan (Synonym: Guaifenesin and Dextromethorphan Hydrobromide)[3] D00848 (Name: Dextromethorphan hydrobromide),
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 13, 46
6Dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg[3] Dextromethorphan (Synonym: Guaifenesin and Dextromethorphan Hydrobromide),
Quinidine,
Sulfate ion		[7] D00642 ,
D00643 ,
D00848 (Name: Dextromethorphan hydrobromide),
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[2] 2, 13
7Dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg[3] Dextromethorphan (Synonym: Guaifenesin and Dextromethorphan Hydrobromide),
Quinidine,
Sulfate ion		[7] D00642 ,
D00643 ,
D00848 (Name: Dextromethorphan hydrobromide),
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[2] 2, 13
8Dextromethorphan/Quinidine
(Synonym: Dextromethorphan hydrobromide)		[2] Dextromethorphan (Synonym: Guaifenesin and Dextromethorphan Hydrobromide),
Quinidine		[7] D00642 ,
D00643 ,
D00848 (Name: Dextromethorphan hydrobromide),
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[1] 13
9Dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg)
(Synonym: Dextromethorphan hydrobromide)		[2] Dextromethorphan (Synonym: Guaifenesin and Dextromethorphan Hydrobromide),
Quinidine		[7] D00642 ,
D00643 ,
D00848 (Name: Dextromethorphan hydrobromide),
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[1] 8
10Dimebon + Dextromethorphan
(Synonym: Dextromethorphan hydrobromide)		[2] Dextromethorphan (Synonym: Guaifenesin and Dextromethorphan Hydrobromide),
Latrepirdine		[4] D00848 (Name: Dextromethorphan hydrobromide),
D03742 ,
D03744 ,
D09917 		[7] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8