Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Baseline disease modifying therapies (DMTs)----[1] 13
2BG00012 (DMF)----[1] 13
3BG00012 (DMF) (Tecfidera®.)----[1] 13
4Biologic DMARD----[2] 46, 271
5Biological DMARDs----[2] 86, 107
6Classic DMARDs treatment group----[1] 46
7Co-medication: Synthetic DMARDs----[1] 46
8Combination of DMARDs----[1] 107
9Conventional DMARD combination----[1] 46
10Conventional DMARDs----[1] 46
11Conventional Synthetic DMARD----[1] 46
12CP-690-550-10 (DMID D1600180)----[1] 107
13Daunorubicin
(Synonym: DM)		[1] Daunorubicin[2] D01264 ,
D07776 (Name: DM)		[2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[1] 65
14Dextromethorphan
(Synonym: Benylin DM (TN))		[1] Dextromethorphan (Synonym: Cough Control DM Max)[3] D00848 (Name: Benylin DM (TN)),
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
15Dextromethorphan 30 mg
(Synonym: Benylin DM (TN))		[1] Dextromethorphan (Synonym: Cough Control DM Max)[3] D00848 (Name: Benylin DM (TN)),
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 96, 97
16Dextromethorphan and Caffeine
(Synonym: Benylin DM (TN))		[2] Caffeine,
Dextromethorphan (Synonym: Cough Control DM Max)		[5] D00528 ,
D00848 (Name: Benylin DM (TN)),
D01453 ,
D03742 ,
D03744 		[17] ADORA1,
ADORA2A,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A,
SIGMAR1 💬		[37] Alcoholism, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Huntington disease, Insulin signaling pathway, Long-term potentiation, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 78
17Dextromethorphan HBr and quinidine sulfate
(Synonym: Benylin DM (TN))		[3] Dextromethorphan (Synonym: Cough Control DM Max),
Quinidine,
Sulfate ion		[7] D00642 ,
D00643 ,
D00848 (Name: Benylin DM (TN)),
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[1] 2
18DEXTROMETHORPHAN HYDROBROMIDE
(Synonym: Benylin DM (TN))		[1] Dextromethorphan (Synonym: Cough Control DM Max)[3] D00848 (Name: Benylin DM (TN)),
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 13, 46
19Dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg
(Synonym: Benylin DM (TN))		[3] Dextromethorphan (Synonym: Cough Control DM Max),
Quinidine,
Sulfate ion		[7] D00642 ,
D00643 ,
D00848 (Name: Benylin DM (TN)),
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[2] 2, 13
20Dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg
(Synonym: Benylin DM (TN))		[3] Dextromethorphan (Synonym: Cough Control DM Max),
Quinidine,
Sulfate ion		[7] D00642 ,
D00643 ,
D00848 (Name: Benylin DM (TN)),
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[2] 2, 13
21Dextromethorphan/Quinidine
(Synonym: Benylin DM (TN))		[2] Dextromethorphan (Synonym: Cough Control DM Max),
Quinidine		[7] D00642 ,
D00643 ,
D00848 (Name: Benylin DM (TN)),
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[1] 13
22Dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg)[2] Dextromethorphan (Synonym: Cough Control DM Max),
Quinidine		[7] D00642 ,
D00643 ,
D00848 (Name: Benylin DM (TN)),
D02272 ,
D03742 ,
D03744 ,
D08458 		[11] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SIGMAR1 💬		[22] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[1] 8
23Diagnostic Test: DM1-ActivC----[1] 113
24Dimebon + Dextromethorphan
(Synonym: Benylin DM (TN))		[2] Dextromethorphan (Synonym: Cough Control DM Max),
Latrepirdine		[4] D00848 (Name: Benylin DM (TN)),
D03742 ,
D03744 ,
D09917 		[7] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[22] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
25Dimethyl Fumarate (DMF)[1] Dimethyl fumarate[1] D03846 [1] KEAP1 💬[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[3] 13, 51, 86
26Dimethyl fumarate [DMF][1] Dimethyl fumarate[1] D03846 [1] KEAP1 💬[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[1] 13
27Dimethyl sulfoxide (DMSO)[1] Dimethyl sulfoxide (Synonym: DMSO)[1] D01043 --[1] 226
28Disease modifying treatment (DMT)----[1] 13
29Disease-modifying antirheumatic drugs (DMARDs)----[1] 46
30DM----[2] 6, 8
31DM-1992----[1] 6
32DMARD----[1] 46
33DMARD cessation----[1] 46
34DMARD maintenance----[1] 46
35DMARD Therapy----[1] 46
36DMARDS----[2] 46, 271
37DMARDs (disease-modifying antirheumatic drugs)----[1] 46
38DMARDs (methotrexate[1] Methotrexate[2] D00142 ,
D02115 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
39DMARDs or Biologics----[1] 46
40DMPS[1] 2,3-Dimercapto-1-propanesulfonic acid (Synonym: DMPS)---[1] 171
41DMSA[1] Succimer (Synonym: DMS-A)[1] D00572 --[1] 171
42DMSO[1] Dimethyl sulfoxide (Synonym: DMSO)[1] D01043 --[1] 226
43DMSO cocktail[1] Dimethyl sulfoxide (Synonym: DMSO)[1] D01043 --[1] 226
44DMT----[1] 13
45DMT continuation----[1] 13
46DMX-200----[1] 222
47Etanercept, other Biologics, Disease-modifying antirheumatic drugs (DMARDs), etc[1] Etanercept[1] D00742 [2] LTA,
TNF 💬		[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
48Exposure to one or more disease-modifying drug(s)(DMDs) used to treat MS----[1] 13
49First line DMT----[1] 13
50HUC-MSC + DMARDs----[1] 46
51Injectable MS DMT----[1] 13
52IONIS-DMPKRx----[1] 113
53Non-biologic Disease Modifying Anti-Rheumatic Drug (DMARD)----[1] 46
54Non-Biologic DMARDs----[3] 46, 86, 107
55Non-biological DMARD's----[1] 46
56Non-biological DMARDs----[1] 46
57Nonbiologic DMARDs of investigator's choice----[1] 46
58Other DMARDs----[1] 46
59Other: DMT withdrawal----[1] 13
60Other: Group 2 (DMARDS treated group)----[1] 46
61Other: Other: Disease modifying therapies (DMT)----[1] 13
62Patient treated with DMARD----[1] 46
63Permitted DMARDs----[1] 46
64Phase 1: Conventiaonal DMARD----[1] 46
65Rheumatoid Arthritis With Disease-Modifying Drugs (DMARDs)----[1] 46
66Standard DMARDs (Disease Modifying Anti Rheumatic Drugs)----[1] 46
67Standard MS DMT----[1] 13
68Standard MS DMTs----[1] 13
69Synthetic DMARD(s)----[1] 46
70Therapy with disease-modifying anti rheumatic drugs (DMARD)----[1] 46
71TNF-a antagonists, non-TNFs, DMARD non-biologics----[2] 46, 271
72UC-MSC+DMARDS----[1] 46
73Vinblastine, vincristine, prednisone, daunorubicin
(Synonym: DM)		[4] Daunorubicin,
Prednisone,
Vinblastine,
Vincristine		[7] D00473 ,
D01068 ,
D01264 ,
D02197 ,
D07776 (Name: DM),
D08675 ,
D08679 		[12] NR3C1,
TOP2A,
TOP2B,
TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[12] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Neuroactive ligand-receptor interaction, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Platinum drug resistance, Prion disease, Salmonella infection 💬[1] 65