Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Acthar high dose (80 U)[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 49
2Administration of a high dose of desipramine[1] Desipramine[2] D00812 ,
D07791 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 156
3Ambrisentan - high dose[1] Ambrisentan[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
4AXO-AAV-GM2 High Dose----[1] 19
5BI 655064 high dose----[1] 46
6BIIL 284 BS high dose----[1] 46
7BIIL 284 BS, high dose----[1] 299
8BIIL 284 BS, high dose, adult patients----[1] 299
9BIIL 284 BS, high dose, pediatric patients----[1] 299
10BIRB 796 BS, high dose----[1] 46
11BLI-1300 high dose----[1] 96
12Brazikumab high dose[1] Brazikumab[1] D10912 [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[1] 96
13Clobazam High Dose[1] Clobazam[1] D01253 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144
14CVN424 High Dose----[1] 6
15CVT-301 High Dose----[1] 6
16DNS-7801 (high dose)----[1] 6
17Elamipretide (high dose)[1] Elamipretide[1] D10925 --[1] 21
18EUR-1008 (APT-1008) High Dose----[1] 298
19Fentanyl (High Dose)[1] Fentanyl[2] D00320 ,
D01399 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 215
20High dose----[1] 97
21High dose AFFITOPE® PD03A + Adjuvant----[1] 6
22High dose ANAVEX2-73----[1] 6
23High Dose Aspirin (1300 mg/day)[1] Acetylsalicylic acid[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 13
24High dose BIBF 1120 twice daily----[1] 85
25High Dose Budesonide[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
26High dose budesonide suspension[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 98
27High dose budesonide tablet[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 98
28High dose Dexamethasone pulses[1] Dexamethasone[9] D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 63
29High dose lactulose[1] Lactulose[1] D00352 --[1] 291
30High dose levodopa[1] Levodopa[1] D00059 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
31High Dose Mesenchymal Stem Cells (MSCs)----[1] 49
32High Dose MT-1303----[1] 97
33High dose of BIIL 284 BS tablets----[1] 46
34High dose of budesonide[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 299
35High dose ORTD-1----[1] 46
36High dose TSO----[1] 96
37High dose vehicle control----[1] 46
38High Dose-VIS649----[1] 66
39High doses of Thiamine y Biotin[2] Biotin,
Thiamine		[2] D00029 ,
D08580 		--[1] 8
40HMPL-004 high dose----[1] 97
41IgPro20 (high dose)----[1] 14
42KPS-0373, High dose----[1] 18
43KW-6356 High Dose----[1] 6
44LiRIS low dose and LiRIS high dose----[1] 226
45LX3305 high dose----[1] 46
46M5049 high dose----[1] 49
47MEDI7183 high dose----[1] 97
48MMX Mesalamine/Mesalazine (High Dose)[1] Mesalazine[1] D00377 --[1] 97
49MT-1303 High dose----[1] 49
50MT-7117 High Dose----[1] 254
51MultiStem high dose[1] MultiStem---[1] 97
52Non-myeloablative high dose immunosuppressive therapy conditioning (HDIT)----[1] 49
53OCU400 High Dose----[1] 90
54PF-06649751 high dose (15 mg QD)[1] Tavapadon[1] D11431 [2] DRD1,
DRD5 💬		[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
55PXT3003 High Dose----[1] 10
56Ravicti high dose[1] Glycerol phenylbutyrate[1] D10127 --[1] 299
57SA001 High dose----[1] 53
58SEN0014196 (High Dose)----[1] 8
59SHR1459 High Dose----[1] 222
60TAS5315 high dose----[1] 46
61Vitamin D3 - high dose[1] Cholecalciferol[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 6
62YRA-1909 high dose----[1] 46