Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1150-mg IVACAFTOR[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
2150mg IVACAFTOR[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
375-mg IVACAFTOR[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
4CF patients with a G551D mutation and treated with Ivacaftor[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
5Deuterated Ivacaftor[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
6Elexacaftor-tezacaftor-ivacaftor exposure[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 (Name: Ivacaftor),
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
7Elexacaftor/tezacaftor/ivacaftor[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 (Name: Ivacaftor),
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
8IVACAFTOR[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
9Ivacaftor (proposed INN)[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
10Ivacaftor 125mg tablet[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
11Ivacaftor 150 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
12Ivacaftor 150 mg or 250 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
13Ivacaftor 25 mg/75 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
14IVACAFTOR 59,5mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
15IVACAFTOR 59.5mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
16Ivacaftor 75 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
17Ivacaftor 75 mg/150 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
18IVACAFTOR 75mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
19Ivacaftor Exposed[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
20Ivacaftor or elexacaftor/tezacaftor/ivacaftor[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 (Name: Ivacaftor),
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
21Ivacaftor+lumacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
22Ivacaftor/Ataluren[2] Ataluren,
Ivacaftor		[2] D09323 ,
D09916 (Name: Ivacaftor)		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
23Ivacaftor/Kalydeco[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
24Ivacaftor/Trikafta[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
25Lumacaftor / ivacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
26Lumacaftor plus Ivacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
27Lumacaftor Plus Ivacaftor Combination[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
28Lumacaftor, Ivacaftor Drug Combination[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
29Lumacaftor-ivacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
30Lumacaftor-Ivacaftor treatment[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
31Lumacaftor/Ivacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
32Lumacaftor/ivacaftor 100mg/125mg tablets[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
33Lumacaftor/ivacaftor 200mg/125mg[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
34Lumacaftor/ivacaftor 200mg/125mg tablets[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
35Lumacaftor/ivacaftor 200mg/83mg tablet[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
36Orkambi: contains lumacaftor and ivacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
37Tezacaftor/Ivacaftor[2] Ivacaftor,
Tezacaftor		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
38Tezacaftor/Ivacaftor + Ivacaftor[2] Ivacaftor,
Tezacaftor		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
39Tezacaftor/Ivacaftor 100mg/150mg[2] Ivacaftor,
Tezacaftor		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
40Tezacaftor/Ivacaftor/100mg/150mg[2] Ivacaftor,
Tezacaftor		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
41Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor[4] Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor		[4] D09916 (Name: Ivacaftor),
D10134 ,
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
42VX-659/Tezacaftor/Ivacaftor[3] Ivacaftor,
Tezacaftor,
VX-659		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
43VX-661 Plus Ivacaftor Combination[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
44VX-661/Ivacaftor[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
45VX-661/ivacaftor (VX-770) 100mg/150 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
46VX-661/ivacaftor 100 mg/ 150 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
47VX-661/ivacaftor 100mg/150 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
48VX-661/ivacaftor 100mg/150mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
49VX-661/ivacaftor 50 mg/ 75 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299