Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1ACT-064992 (macitentan)
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
2ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(Synonym: Opsumit (TN))		[4] Bosentan,
Macitentan (Synonym: Opsumit),
Sildenafil,
Tadalafil		[6] D01227 ,
D02008 ,
D02229 ,
D07538 ,
D08514 ,
D10135 (Name: Opsumit (TN))		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
3FDC macitentan/tadalafil
(Synonym: Opsumit (TN))		[2] Macitentan (Synonym: Opsumit),
Tadalafil		[2] D02008 ,
D10135 (Name: Opsumit (TN))		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
4Macitentan
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 51, 85, 86, 88, 210
5Macitentan (ACT-064992)
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
6Macitentan 10 mg
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 86, 88
7Macitentan 10 mg tablet, once daily.
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
8Macitentan 10mg
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 88
9Macitentan 3 mg
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
10Macitentan 37.5 mg
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
11Macitentan 3mg
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
12Macitentan 75 mg
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
13MACITENTAN COMPRESSE
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 86, 88
14Macitentan Group
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
15MACITENTAN TABLETS
(Synonym: Opsumit (TN))		[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 86, 88
16Observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi[4] Epoprostenol,
Iloprost,
Macitentan (Synonym: Opsumit),
Selexipag		[5] D00106 ,
D01337 ,
D02721 ,
D09994 ,
D10135 (Name: Opsumit (TN))		[3] EDNRA,
EDNRB,
PTGIR 💬		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Platelet activation, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
17Opsumit[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 86, 88, 210
18Opsumit (macitentan)[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
19Opsumit 10 Mg Tablet----[1] 51
20Opsumit®[1] Macitentan (Synonym: Opsumit)[1] D10135 (Name: Opsumit (TN))[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 86, 88, 210