Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
120 mg sildenafil citrate by mouth[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
25% sildenafil cream[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 50
3Access program - sildenafil citrate, Viagra, Revatio[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
4Bosentan and Sildenafil[2] Bosentan,
Sildenafil		[4] D01227 ,
D02229 (Name: Sildenafil citrate),
D07538 ,
D08514 (Name: Sildenafil)		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
5Duo-Therapy with Sildenafil + Bosentan[2] Bosentan,
Sildenafil		[4] D01227 ,
D02229 (Name: Sildenafil citrate),
D07538 ,
D08514 (Name: Sildenafil)		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
6ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)[4] Bosentan,
Macitentan,
Sildenafil,
Tadalafil		[6] D01227 ,
D02008 ,
D02229 (Name: Sildenafil citrate),
D07538 ,
D08514 (Name: Sildenafil),
D10135 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
7G04BE03- Sildenafil - sildenafil (citrato)[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
8Mono-Therapy with Sildenafil[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
9Oral sildenafil[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
10Other: Standard of Care Sildenafil[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 90, 301
11SILDENAF----[1] 86
12Sildenafil[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
13Sildenafil (50 mg)[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 85
14Sildenafil (Acute-1 hour)[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299
15Sildenafil (as citrate)[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
16Sildenafil (REVATIO)[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
17Sildenafil (Revatio) 20 mg TID[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
18Sildenafil (Subchronic-4 weeks)[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299
19Sildenafil 20 mg tablets[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 278
20Sildenafil 20mg[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 51, 86
21Sildenafil 20mg and Bosentan 62.5mg[2] Bosentan,
Sildenafil		[4] D01227 ,
D02229 (Name: Sildenafil citrate),
D07538 ,
D08514 (Name: Sildenafil)		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86
22Sildenafil 40mg oral capsule[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299
23Sildenafil and Losartan[2] Losartan,
Sildenafil		[4] D00357 ,
D02229 (Name: Sildenafil citrate),
D08146 ,
D08514 (Name: Sildenafil)		[2] AGTR1,
PDE5A 💬		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 85
24Sildenafil by injection[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 210
25Sildenafil citrate[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[4] 51, 85, 86, 225
26Sildenafil citrate (UK-92,480)[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
27Sildenafil Filmtabletten[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
28Sildenafil singly or in association with Bosentan[2] Bosentan,
Sildenafil		[4] D01227 ,
D02229 (Name: Sildenafil citrate),
D07538 ,
D08514 (Name: Sildenafil)		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
29Sildenafil therapy[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 51
30Sildenafil25 mg----[1] 17
31SILDENAFILO[1] Sildenafil[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
32Sitaxsentan and Sildenafil[2] Sildenafil,
Sitaxentan		[3] D02229 (Name: Sildenafil citrate),
D07171 ,
D08514 (Name: Sildenafil)		[2] EDNRA,
PDE5A 💬		[9] Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
33Sodium tanshinone IIA sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth[2] Dextrose, unspecified form,
Sildenafil		[2] D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
34Tadalafil and Sildenafil[2] Sildenafil,
Tadalafil		[3] D02008 ,
D02229 (Name: Sildenafil citrate),
D08514 (Name: Sildenafil)		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 113