Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Ambrisentan plus Spironolactone[2] Ambrisentan,
Spironolactone		[2] D00443 (Name: Spironolactone),
D07077 		[2] EDNRA,
NR3C2 💬		[8] Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
2Spironolactone[1] Spironolactone[1] D00443 (Name: Spironolactone)[1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[7] 58, 67, 86, 113, 210, 218, 225
3Spironolactone (drug)[1] Spironolactone[1] D00443 (Name: Spironolactone)[1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[1] 210
4Spironolactone and conivaptan[2] Conivaptan,
Spironolactone		[3] D00443 (Name: Spironolactone),
D01236 ,
D07748 		[3] AVPR1A,
AVPR2,
NR3C2 💬		[6] Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬[1] 86
5Spironolactone captopril carvedilol[3] Captopril,
Carvedilol,
Spironolactone		[4] D00251 ,
D00255 ,
D00443 (Name: Spironolactone),
D03415 		[7] ACE,
ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2,
NR3C2 💬		[19] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Chagas disease, Chemical carcinogenesis - receptor activation, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hypertrophic cardiomyopathy, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86