Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1100 mg ELX (VX-445) / 50 mg TEZ / 75 mg IVA FDC----[1] 299
2100 mg ELX /50 mg TEZ /75 mg IVA FDC----[1] 299
3100 mg ELX/50 mg TEZ /75 mg IVA FDC----[1] 299
4100 mg ELX/50 mg TEZ/75 mg IVA fixed dose combination----[1] 299
5100 mg TEZ/150 mg IVA FDC----[1] 299
6100 mg VX-445 /50 mg TEZ/75 mg IVA FDC----[1] 299
7100 mg VX-445/50 mg TEZ /75 mg IVA FDC----[1] 299
8100-mg ELX (VX-445) / 50-mg TEZ / 75-mg IVA FDC----[1] 299
9100-mg ELX (VX-455) / 50-mg TEZ / 75-mg IVA FDC----[1] 299
10100-mg ELX / 50-mg TEZ / 75 -mg----[1] 299
11100-mg ELX / 50-mg TEZ / 75 -mg IVA FDC----[1] 299
12100-mg VX-445 / 50-mg TEZ / 75- mg IVA FDC----[1] 299
13100-mg VX-445 / 50-mg TEZ / 75-mg IVA FDC----[1] 299
14100-mg VX-445 /50-mg TEZ/75-mg----[1] 299
15100-mg VX-445/50-mg TEZ/75-mg IVA FDC----[1] 299
16100g ELX / 50mg TEZ / 75mg IVA----[1] 299
17100mg ELX/50mg TEZ /75mg IVA----[1] 299
18100mg VX-445/50mg TEZ /75mg IVA FDC----[1] 299
1950 mg ELX/25 mg TEZ/37.5 mg IVA----[1] 299
2050 mg ELX/25 mg TEZ/37.5 mg IVA fixed dose combination----[1] 299
2180mg ELX / 40mg TEZ / 60mg IVA----[1] 299
22Elexacaftor-tezacaftor-ivacaftor exposure[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 ,
D11041 (Name: Tezacaftor),
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
23Elexacaftor/tezacaftor/ivacaftor[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 ,
D11041 (Name: Tezacaftor),
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
24ELX (VX-445)/TEZ (VX-661)/IVA (VX-770)----[1] 299
25ELX/TEZ/IVA----[1] 299
26Ivacaftor or elexacaftor/tezacaftor/ivacaftor[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 ,
D11041 (Name: Tezacaftor),
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
27TEZ----[1] 299
28TEZ/IVA----[1] 299
29TEZACAFTOR[1] Tezacaftor[1] D11041 (Name: Tezacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
30Tezacaftor (TEZ)[1] Tezacaftor[1] D11041 (Name: Tezacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
31Tezacaftor/Ivacaftor[2] Ivacaftor,
Tezacaftor		[2] D09916 ,
D11041 (Name: Tezacaftor)		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
32Tezacaftor/Ivacaftor + Ivacaftor[2] Ivacaftor,
Tezacaftor		[2] D09916 ,
D11041 (Name: Tezacaftor)		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
33Tezacaftor/Ivacaftor 100mg/150mg[2] Ivacaftor,
Tezacaftor		[2] D09916 ,
D11041 (Name: Tezacaftor)		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
34Tezacaftor/Ivacaftor/100mg/150mg[2] Ivacaftor,
Tezacaftor		[2] D09916 ,
D11041 (Name: Tezacaftor)		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
35Tezosentan[1] Tezosentan---[1] 86
36Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor[4] Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor		[4] D09916 ,
D10134 ,
D11041 (Name: Tezacaftor),
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
37VX-121/TEZ/D-IVA----[1] 299
38VX-121/tezacaftor/deutivacaftor[2] Deutivacaftor,
Tezacaftor		[2] D11041 (Name: Tezacaftor),
D11423 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
39VX-445 / TEZ / IVA----[1] 299
40VX-445 / TEZ / IVA FDC----[1] 299
41VX-445 /TEZ/IVA----[1] 299
42VX-445/TEZ/IVA----[1] 299
43VX-659/ TEZ/IVA[1] VX-659---[1] 299
44VX-659/TEZ/IVA[1] VX-659---[1] 299
45VX-659/Tezacaftor/Ivacaftor[3] Ivacaftor,
Tezacaftor,
VX-659		[2] D09916 ,
D11041 (Name: Tezacaftor)		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
46VX-661/VX-770 (TEZ/IVA)----[1] 299