Drug Description in Trials / DrugBank / KEGG DRUG


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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1**Comment**- IMP inhalation solution identical to ventavis inhalation solution, but IMP is in a different volume presentation. Please see covering letter.[1] Iloprost[1] D02721 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
21 mg QD to 15 mg QD PF-06649751[1] Tavapadon[1] D11431 [2] DRD1,
DRD5 💬
[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
31 mg QD to 7 mg QD PF-06649751 (if de-escalated in parent study)[1] Tavapadon[1] D11431 [2] DRD1,
DRD5 💬
[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
410% Metronidazole Ointment
(Synonym: METRONIDAZOLE TOPICAL GEL)
[1] Metronidazole (Synonym: Metronidazole Topical Gel)[3] D00409 (Name: METRONIDAZOLE TOPICAL GEL),
D05016 ,
D05017
--[1] 96
515 mg QD de-escalated to 7 mg QD PF-06649751 in parent study remain at 7 mg QD[1] Tavapadon[1] D11431 [2] DRD1,
DRD5 💬
[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
615N2-tofacitinib[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 97
73 mg QD to 15 mg QD PF-06649751[1] Tavapadon[1] D11431 [2] DRD1,
DRD5 💬
[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
83 mg QD to 7 mg QD PF-06649751 (de-escalated in parent study)[1] Tavapadon[1] D11431 [2] DRD1,
DRD5 💬
[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
93H-cholesterol bound to albumin[1] Cholesterol[1] D00040 --[2] 259, 261
107 mg QD to 15 mg QD PF-06649751[1] Tavapadon[1] D11431 [2] DRD1,
DRD5 💬
[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
117 mg QD to 7 mg QD PF-06649751 (de-escalated in parent study)[1] Tavapadon[1] D11431 [2] DRD1,
DRD5 💬
[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
12[F-18] Fluorodopa Positron Emission Tomography----[1] 6
13Abatacept, rituximab or tocilizumab[3] Abatacept,
Rituximab,
Tocilizumab
[3] D02596 (Name: Tocilizumab),
D02994 ,
D03203
[4] CD80,
CD86,
IL6R,
MS4A1 💬
[24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
14ABP 710 - Biosimilar to infliximab[1] Infliximab[1] D02598 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
15ABP 798 - Biosimilar to rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 46
16ABP 798 Biosimilar to Rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 46
17ABP 959 - biosimilar to eculizumab[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
18ABP 959 - proposed biosimilar to eculizumab[1] Eculizumab[1] D03940 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 62
19AC-203 1% Topical Ointment----[1] 162
20Active topical NS2 1% dermatologic cream----[1] 160
21Adalimuab, Etanercept, Tocilizumab, or Abatacept[3] Abatacept,
Etanercept,
Tocilizumab
[3] D00742 ,
D02596 (Name: Tocilizumab),
D03203
[5] CD80,
CD86,
IL6R,
LTA,
TNF 💬
[79] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cell adhesion molecules, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
22Adalimumab (up to 9 months exposure)[1] Adalimumab[1] D02597 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
23ADENO-ASSOCIATED VIRUS SEROTYPE 5 ENCODING A MICRORNA TARGETED TO HUMAN HUNTINGTIN GENE----[1] 8
24ADX-102 1% Topical Dermal Cream (reproxalap)[1] Reproxalap[1] D11309 --[1] 160
25Alpha-tocopherol[2] Tocopherol,
Vitamin E (Synonym: alpha-tocopherol)
[2] D02331 ,
D02332 (Name: Tocopherol)
--[2] 49, 206
26Alpha-tocotrienol quinone[1] Tocotrienol---[2] 21, 156
27Alpha-tocotrienolquinone----[1] 18
28Also referred to as 'MEDI2070'----[2] 96, 97
29Also referred to as MED2070----[1] 96
30Also referred to as MEDI2070----[2] 96, 97
31Alvelestat tosylate[1] Alvelestat---[1] 231
32Amoxicillin, metronidazole and doxycycline
(Synonym: METRONIDAZOLE TOPICAL GEL)
[3] Amoxicillin,
Doxycycline,
Metronidazole (Synonym: Metronidazole Topical Gel)
[11] D00229 ,
D00307 ,
D00409 (Name: METRONIDAZOLE TOPICAL GEL),
D02129 ,
D02925 ,
D03903 ,
D03904 ,
D05016 ,
D05017 ,
D07452 ,
D07876
--[1] 97
33AndroGel 1 % Topical Gel----[1] 13
34Anesthetic Topical Adhesive Synera----[1] 13
35Antiepileptic drug (1 to 3 only)----[1] 158
36Apitox - pure honeybee toxin----[1] 13
37Ascorbic Acid (Vitamin C) and Alpha-tocopherol (Vitamin E)[3] Ascorbic acid (Synonym: Tobakient),
Tocopherol,
Vitamin E (Synonym: alpha-tocopherol)
[3] D00018 ,
D02331 ,
D02332 (Name: Tocopherol)
--[1] 206
38Atomoxetine
(Synonym: Tomoxetine)
[1] Atomoxetine (Synonym: Tomoxetina)[2] D02574 (Name: Tomoxetine hydrochloride),
D07473 (Name: Tomoxetine)
[1] SLC6A2 💬[1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17
39Autologous mature tolerogenic monocyte-derived Dendritic Cells loaded with the B29 peptide of HSP70----[1] 46
40Autologous VitD3 tolerogenic monocyte-derived dendritic cells loaded with a pool of myelin peptides (tolDC-VitD3)----[1] 13
41Avonex and Topamax[1] Interferon beta-1a[1] D04554 [2] IFNAR1,
IFNAR2 💬
[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 13
42Azithromycin + Metronidazole
(Synonym: METRONIDAZOLE TOPICAL GEL)
[2] Azithromycin,
Metronidazole (Synonym: Metronidazole Topical Gel)
[6] D00409 (Name: METRONIDAZOLE TOPICAL GEL),
D02134 ,
D05016 ,
D05017 ,
D06390 ,
D07486
--[1] 96
43BDMARD withdrawal (etanercept, adalimumab, infliximab, certolizumab, golimumab, tozilizumab, abatacept)[5] Abatacept,
Adalimumab,
Etanercept,
Golimumab,
Infliximab
[5] D00742 ,
D02597 ,
D02598 ,
D03203 ,
D04358
[4] CD80,
CD86,
LTA,
TNF 💬
[73] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cell adhesion molecules, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
44Behavioral: Physical Activity Together for PwMS and their CGs (PAT-MS)----[1] 13
45Behavioral: pre DBS patients responding to the DBS-PS scale----[1] 6
46Behavioral: Tobacco Treatment Specialist (TTS) intervention[1] Tobacco leaf---[1] 299
47Bezafibrate (400mg) in addition to standard 15-20 mg/kg/jour UDCA therapy[2] Bezafibrate,
Ursodeoxycholic acid (Synonym: BAMBOO SALT Eunganggo Jook Yeom Toothpaste)
[2] D00734 ,
D01366
[2] NR1H4,
PPARA 💬
[11] Adipocytokine signaling pathway, Alcoholic liver disease, Bile secretion, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[1] 94
48BIIB067 (Tofersen)[1] Tofersen[1] D11811 (Name: Tofersen)[1] SOD1 💬[8] Amyotrophic lateral sclerosis, Chemical carcinogenesis - reactive oxygen species, Huntington disease, Longevity regulating pathway - multiple species, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Peroxisome, Prion disease 💬[1] 2
49Biological: Benralizumab, Biological: Placebo to Mepolizumab[2] Benralizumab,
Mepolizumab
[2] D04923 ,
D09874
[2] IL5,
IL5RA 💬
[13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[1] 44
50Biological: Mepolizumab, Biological: Placebo to Benralizumab[2] Benralizumab,
Mepolizumab
[2] D04923 ,
D09874
[2] IL5,
IL5RA 💬
[13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[1] 44
51Biosimilar product to adalimumab[1] Adalimumab[1] D02597 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
52Bony Toxicity----[1] 34
53Bortezomib D-mannitol
(Synonym: Tobrex (TN))
[2] Bortezomib,
Mannitol
[2] D00062 (Name: Tobrex (TN)),
D03150
[1] PSMB5 💬[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[1] 28
54Botulinic toxin----[1] 36
55Botulinum A toxin----[1] 118
56Botulinum Toxin----[3] 6, 13, 149
57Botulinum toxin A[1] Botulinum toxin type A[1] D00783 (Name: Botulinum toxin type A)[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[4] 13, 51, 149, 226
58BOTULINUM TOXIN A - HAEMAGGLUTININ COMPLEX[1] Botulinum toxin type A[1] D00783 (Name: Botulinum toxin type A)[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 13
59BOTULINUM TOXIN TYPE A[1] Botulinum toxin type A[1] D00783 (Name: Botulinum toxin type A)[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[10] 2, 5, 6, 7, 13, 15, 17, 70, 113, 149
60Botulinum toxin type A (Nabota®) injection into the gastrocnemius muscle[1] Botulinum toxin type A[1] D00783 (Name: Botulinum toxin type A)[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 70
61Botulinum Toxin Type A 200U[1] Botulinum toxin type A[1] D00783 (Name: Botulinum toxin type A)[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 13
62Botulinum Toxin Type A 300U[1] Botulinum toxin type A[1] D00783 (Name: Botulinum toxin type A)[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 13
63Botulinum toxin type A infiltrations[1] Botulinum toxin type A[1] D00783 (Name: Botulinum toxin type A)[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 13
64Botulinum toxin type B[1] Botulinum toxin type B[1] D02735 (Name: Botulinum toxin type B (JAN))[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[3] 2, 6, 51
65Botulinum toxin type B (2500 units / vial)[1] Botulinum toxin type B[1] D02735 (Name: Botulinum toxin type B (JAN))[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 51
66Botulinum toxin type B (Myobloc)[1] Botulinum toxin type B[1] D02735 (Name: Botulinum toxin type B (JAN))[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[2] 2, 6
67Botulinum toxin(Botox)[1] Botulinum toxin type A[1] D00783 (Name: Botulinum toxin type A)[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 51
68Botulinum Toxin: Xeomin[1] Botulinum toxin type A[1] D00783 (Name: Botulinum toxin type A)[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 6
69Botulism Toxin Treatment----[1] 161
70BT051 up to 3200 mg----[1] 97
71C-82 Topical Gel, 1%----[1] 51
72C-TYPE NATRIURETIC PEPTIDE CONJUGATED TO MULTI-ARM POLYETHYLENE GLYCOL CARRIER THROUGH A CLEAVABLE LINKER[1] Polyethylene glycol (Synonym: Topcare ClearLax)[1] D03370 --[1] 276
73Ceftazidime and tobramycin[2] Ceftazidime,
Tobramycin
[4] D00063 (Name: Tobramycin),
D00921 ,
D02542 (Name: Tobramycin sulfate),
D07654
--[1] 299
74Chong Kun Dang Tofacitinib Tablet[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
75Cistanche Total Glycosides----[1] 2
76Clindamycin
(Synonym: CLINDAMYCIN PHOAPHATE TOPICAL SOLUTION USP, 1%)
[1] Clindamycin (Synonym: Biacna Topical Gel)[4] D00277 ,
D01073 (Name: CLINDAMYCIN PHOAPHATE TOPICAL SOLUTION USP, 1%),
D01990 ,
D02132
--[2] 46, 299
77Clobetasol 0.05% Topical Ointment[1] Clobetasol[1] D07715 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 162
78CLOSTRIDIUM BOTULINUM TOXIN TYPE A[2] Botulinum toxin type A,
Clostridium botulinum
[1] D00783 (Name: Botulinum toxin type A)[1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 13
79Cohort 1: hATG, CsA, EPAG Day 14 to Month 6[1] Antilymphocyte immunoglobulin (horse)---[1] 60
80Cohort 2: hATG, CsA, EPAG Day 14 to Month 3[1] Antilymphocyte immunoglobulin (horse)---[1] 60
81Cohort 2: Nilotinib Oral Capsules (dose to be determined from Cohort 1)[1] Nilotinib[1] D08953 [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬
[33] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[1] 6
82Cohort 3: hATG, CsA (dose reduced), EPAG day 1 to month 6[1] Antilymphocyte immunoglobulin (horse)---[1] 60
83Combination Product: Beclomethasone dipropionate in addition to MC-EVOO[1] Beclomethasone dipropionate[2] D00689 ,
D07495
[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
84Combination Product: Beclomethasone dipropionate in addition to refined oil[1] Beclomethasone dipropionate[2] D00689 ,
D07495
[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
85Comparator: diclofenac
(Synonym: DICLOFENAC SODIUM TOPICAL SOLUTION)
[1] Diclofenac (Synonym: Topcare Athritis Pain Reliever)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM TOPICAL SOLUTION),
D07816
[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
86Comparator: Diclofenac sodium
(Synonym: DICLOFENAC SODIUM TOPICAL SOLUTION)
[1] Diclofenac (Synonym: Topcare Athritis Pain Reliever)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM TOPICAL SOLUTION),
D07816
[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
87Computed Tomography----[5] 34, 40, 46, 49, 96
88Corticoids+ tocilizumab 8mg/Kg/4 weeks[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
89Cotoretigene Toliparvovec----[1] 90
90CP-690,550 (tofacitinib)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[2] 46, 107
91Cystic Fibrosis Ready to Use Supplemental Food----[1] 299
92D-a-tocopheryl PEG 1000 succinate----[1] 299
93Decrease Tocilizumab, Abatacept[2] Abatacept,
Tocilizumab
[2] D02596 (Name: Tocilizumab),
D03203
[3] CD80,
CD86,
IL6R 💬
[24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
94Denosumab - - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand[1] Denosumab[1] D03684 [1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[1] 274
95Denosumab - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand[1] Denosumab[1] D03684 [1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[1] 274
96Diagnostic Test: 30 seconds sit to stand test----[1] 113
97Diagnostic Test: 68Ga-DOTA-TOC PET/CT----[1] 84
98Diagnostic Test: Antibodies to golimumab[1] Golimumab[1] D04358 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 97
99Diagnostic Test: Beam test to predict falls[1] Tricyclazole---[1] 6
100Diagnostic Test: Candy Glucose Tolerance Test[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 299
101Diagnostic Test: Mixed Meal Tolerance Test----[1] 298
102Diagnostic Test: Ocular Coherence Tomography-Angiography (OCT-A)----[2] 90, 301
103Diagnostic Test: Oral glucose tolerance test[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[3] 13, 65, 299
104Diagnostic Test: Retrospective evaluation of endoscopy prior to study drug----[1] 98
105Diagnostic Test: Serum Metal ion levels determined to monitor changes in chromium and cobalt levels[3] Chromium (Synonym: Swiss Total One),
Cobalt,
Methamidophos
---[1] 46
106Diclofenac
(Synonym: DICLOFENAC SODIUM TOPICAL SOLUTION)
[1] Diclofenac (Synonym: Topcare Athritis Pain Reliever)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM TOPICAL SOLUTION),
D07816
[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
107Diclofenac + Omeprazole
(Synonym: DICLOFENAC SODIUM TOPICAL SOLUTION)
[2] Diclofenac (Synonym: Topcare Athritis Pain Reliever),
Omeprazole (Synonym: Topcare Omeprazole)
[7] D00455 ,
D00903 ,
D00904 (Name: DICLOFENAC SODIUM TOPICAL SOLUTION),
D01207 ,
D05259 ,
D05261 ,
D07816
[4] ATP4A,
ATP4B,
PTGS1,
PTGS2 💬
[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Collecting duct acid secretion, Gastric acid secretion, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxidative phosphorylation, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
108Diclofenac 50 milligrams
(Synonym: DICLOFENAC SODIUM TOPICAL SOLUTION)
[1] Diclofenac (Synonym: Topcare Athritis Pain Reliever)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM TOPICAL SOLUTION),
D07816
[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 271
109Diclofenac Sodium
(Synonym: DICLOFENAC SODIUM TOPICAL SOLUTION)
[1] Diclofenac (Synonym: Topcare Athritis Pain Reliever)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM TOPICAL SOLUTION),
D07816
[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 34, 46
110Diclofenac sodium topical gel[1] Diclofenac (Synonym: Topcare Athritis Pain Reliever)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM TOPICAL SOLUTION),
D07816
[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 13
111Diclofenac SR
(Synonym: DICLOFENAC SODIUM TOPICAL SOLUTION)
[1] Diclofenac (Synonym: Topcare Athritis Pain Reliever)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM TOPICAL SOLUTION),
D07816
[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 271
112Diphtheria toxoid[1] Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)---[2] 13, 46
113DP Mannitol
(Synonym: Tobrex (TN))
[1] Mannitol[1] D00062 (Name: Tobrex (TN))--[1] 299
114Drug: Tocilizmab----[1] 46
115Drug: Topical Rapamycin[1] Sirolimus[1] D00753 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[1] 157
116Dry powder tobramycin[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
117EGCG + Tocotrienol[2] Epigallocatechin gallate,
Tocotrienol
---[1] 299
118Essential amino acid intake + Leucine vs total AA supplement[1] Leucine[1] D00030 --[1] 299
119Etanercepet, Rituximab, Abatacept, Tocilizumab, Sarilumab[4] Abatacept,
Rituximab,
Sarilumab,
Tocilizumab
[4] D02596 (Name: Tocilizumab),
D02994 ,
D03203 ,
D10161
[4] CD80,
CD86,
IL6R,
MS4A1 💬
[24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
120Evaluation of biological predictive factors of clinical response to ustekinumab[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬
[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 96
121Exposure to golimumab[1] Golimumab[1] D04358 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 97
122Exposure to one or more disease-modifying drug(s)(DMDs) used to treat MS----[1] 13
123Fluocinolone Acetonide
(Synonym: FLUOCINOLONE ACETONIDE TOPICAL)
[2] Fluocinolone,
Fluocinolone acetonide (Synonym: Fluocinolone Acetonide Topical)
[1] D01825 (Name: FLUOCINOLONE ACETONIDE TOPICAL)[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 90
124Fourier Domain Doppler Optical Coherence Tomography (FDOCT)----[1] 13
125Frequently Sampled Oral Glucose Tolerance Test and CGM[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 299
126Furosemide
(Synonym: TOXYCOLOGY MEDICATED COLLECTION SYSTEM)
[1] Furosemide (Synonym: TOXYCOLOGY Medicated Collection System)[1] D00331 (Name: TOXYCOLOGY MEDICATED COLLECTION SYSTEM)[1] SLC12A2 💬[3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[1] 6
127Furosemide Injection
(Synonym: TOXYCOLOGY MEDICATED COLLECTION SYSTEM)
[1] Furosemide (Synonym: TOXYCOLOGY Medicated Collection System)[1] D00331 (Name: TOXYCOLOGY MEDICATED COLLECTION SYSTEM)[1] SLC12A2 💬[3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[1] 6
128Gamma-Tocopherol[2] Tocopherol,
gamma-Tocopherol
[1] D02332 (Name: Tocopherol)--[1] 13
129General anesthesia with tourniquet----[1] 46
130General anesthesia without tourniquet----[1] 46
131Glucagon stimulation test and insulin tolerance test[1] Glucagon[2] D00116 ,
D02118
[1] GCGR 💬[2] Glucagon signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 78
132GM-CSF, fosfomycin and metronidazole
(Synonym: METRONIDAZOLE TOPICAL GEL)
[2] Fosfomycin,
Metronidazole (Synonym: Metronidazole Topical Gel)
[7] D00409 (Name: METRONIDAZOLE TOPICAL GEL),
D00925 ,
D02187 ,
D02188 ,
D04253 ,
D05016 ,
D05017
--[1] 97
133HAEMOPHILUS TYPE B CONJUGATE VACCINE (TETANUS TOXOID CONJUGATE)[1] Clostridium tetani toxoid antigen (formaldehyde inactivated)---[2] 13, 14
134High-resolution peripheral quantitative computed tomography (HR-pQCT)----[1] 46
135Home Oral Glucose Tolerance Test kit[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 299
136HOV-12020 (Palm tocotrienols complex)----[1] 124
137Human Monoclonal Antibody (CNTO 1275) to Interleukin 12p-40----[1] 96
138Human monoclonal antibody (CNTO 1275) to interleukin-12p40----[1] 13
139HUMAN SERUM ALBUMIN (HSA) FUSED TO RECOMBINANT HUMAN GROWTH HORMONE (HGH)[2] Albumin human,
Somatotropin
[3] D02691 ,
D02792 ,
D05424
[1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
140Human Serum Albumin (HSA) fused to somatropin[2] Albumin human,
Somatotropin
[3] D02691 ,
D02792 ,
D05424
[1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
141IDPM: Inhaled Dry Powder Mannitol
(Synonym: Tobrex (TN))
[1] Mannitol[1] D00062 (Name: Tobrex (TN))--[1] 299
142IDURONATE-2-SULFATASE FUSED TO A FC POLYPEPTIDE THAT BINDS TO THE HUMAN TRANSFERRIN RECEPTOR----[1] 19
143Iloprost therapy up to 2 ng/kg x min[1] Iloprost[1] D02721 [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 51
144In double-blind phase: treatment with tofacitinib[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 107
145In open-label phase: treatment with tofacitinib[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 107
146Incobotulinum Toxin A----[3] 2, 6, 13
147Inhaled Dry Powder Mannitol
(Synonym: Tobrex (TN))
[1] Mannitol[1] D00062 (Name: Tobrex (TN))--[1] 299
148Inhaled Mannitol
(Synonym: Tobrex (TN))
[1] Mannitol[1] D00062 (Name: Tobrex (TN))--[1] 299
149Inhaled tobramycin[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
150INN-Tocilizumab[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 266
151Insulin glargine
(Synonym: TOUJEO)
[1] Insulin glargine (Synonym: Toujeo)[1] D03250 (Name: TOUJEO)[1] INSR 💬[22] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 299
152Integra TITAN™ Total Shoulder Generation 1.0[1] Titanium---[1] 46
153Interferon beta treatment to add-on atorvastatin treatment[2] Atorvastatin,
Human interferon beta
[3] D00258 ,
D00887 ,
D07474
[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 13
154Intermittent Exposure to Oxygen via Oro-Nasal Mask[1] Oxygen[1] D00003 --[1] 226
155Intra-articular Tocilizumab[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
156Intradetrusor injection of Botulinum Toxin-A----[1] 13
157Intravenous (i.v.) methylprednisolone 1000 mg, total 9[1] Methylprednisolone[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002
[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 222
158Intravenous Infusion of Diclofenac Sodium
(Synonym: DICLOFENAC SODIUM TOPICAL SOLUTION)
[1] Diclofenac (Synonym: Topcare Athritis Pain Reliever)[3] D00903 ,
D00904 (Name: DICLOFENAC SODIUM TOPICAL SOLUTION),
D07816
[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 78
159Intravesical injection of Botulinum A toxin----[2] 6, 17
160IPD® (suplatast tosilate)----[1] 226
161Itraconazole
(Synonym: TOLSURA)
[1] Itraconazole (Synonym: Tolsura)[1] D00350 (Name: TOLSURA)--[5] 3, 65, 96, 227, 299
162Itraconazole 400 mg/day and terbinafine 500 mg/day administered orally.
(Synonym: TOLSURA)
[2] Itraconazole (Synonym: Tolsura),
Terbinafine (Synonym: Terbinafine HCl Chlortimazole and Tolnaftate)
[3] D00350 (Name: TOLSURA),
D02219 ,
D02375
--[1] 96
163Itraconazole/voriconazole
(Synonym: TOLSURA)
[2] Itraconazole (Synonym: Tolsura),
Voriconazole
[2] D00350 (Name: TOLSURA),
D00578
--[1] 299
164IV glucose tolerance test[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 299
165IV tobramycin[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
166Jinarc - Tolvaptan tablets[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
167Ketorolac
(Synonym: Toradol (TN))
[1] Ketorolac (Synonym: Chi-Myst Resolve Topical)[2] D00813 (Name: Toradol (TN)),
D08104 (Name: Toradol (TN))
[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[2] 70, 226
168Ketorolac Tromethamine
(Synonym: Toradol (TN))
[2] Ketorolac (Synonym: Chi-Myst Resolve Topical),
Tromethamine
[3] D00396 ,
D00813 (Name: Toradol (TN)),
D08104 (Name: Toradol (TN))
[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 226
169Lapatinib
(Synonym: Lapatinib tosilate hydrate (JAN))
[1] Lapatinib[2] D04024 (Name: Lapatinib tosilate hydrate (JAN)),
D08108
[2] EGFR,
ERBB2 💬
[50] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬[3] 34, 74, 75
170Lentivirus-mediated delivery of ARSA to the CNS.----[1] 19
171LINQ device - implantable cardiac monitor - referred to in the application as implantable loop recorder or ILR)[1] Methamidophos---[1] 28
172Listed for each disorder below, up to three drugs per disorder (too many characters to list in this field----[1] 13
173LMX 4 Topical Cream----[1] 256
174MabionCD20 (candidate biosimilar to rituximab)[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 46
175Mannitol
(Synonym: Tobrex (TN))
[1] Mannitol[1] D00062 (Name: Tobrex (TN))--[7] 6, 13, 28, 60, 96, 113, 299
176Mannitol + pulmozyme
(Synonym: Tobrex (TN))
[2] Dornase alfa,
Mannitol
[2] D00062 (Name: Tobrex (TN)),
D03896
--[1] 299
177Mannitol inhalation powder
(Synonym: Tobrex (TN))
[1] Mannitol[1] D00062 (Name: Tobrex (TN))--[1] 299
178Manual toothbrush----[1] 51
179Manual toothbrush and water flosser (Philips Sonicare AirFloss)[1] Water (Synonym: Yumaki Original Mint Tooth)[1] D00001 --[1] 51
180Medication to suppress the immune system----[1] 19
181MENINGOCOCCAL GROUP A OLIGOSACCHARIDES CONJUGATED TO CORYNEBACTERIUM DIPHTHERIAE C7 (beta197) M8 (CRM197) PROTEIN[2] Corynebacterium diphtheriae (Synonym: Tetanus and Diphtheria Toxoids Adsorbed),
Corynebacterium diphtheriae CRM197 protein (Synonym: Diphtheria toxin mutant CRM197)
---[1] 11
182MENINGOCOCCAL GROUP A OLIGOSACCHARIDES CONJUGATED TO CORYNEBACTERIUM DIPHTHERIAE C7 (ß197) M8 (CRM197) PROTEIN[2] Corynebacterium diphtheriae (Synonym: Tetanus and Diphtheria Toxoids Adsorbed),
Corynebacterium diphtheriae CRM197 protein (Synonym: Diphtheria toxin mutant CRM197)
---[1] 11
183MENINGOCOCCAL GROUP W OLIGOSACCHARIDES CONJUGATED TO CORYNEBACTERIUM DIPHTHERIAE C7 (beta197) M8 (CRM197) PROTEIN[2] Corynebacterium diphtheriae (Synonym: Tetanus and Diphtheria Toxoids Adsorbed),
Corynebacterium diphtheriae CRM197 protein (Synonym: Diphtheria toxin mutant CRM197)
---[1] 11
184MENINGOCOCCAL GROUP W OLIGOSACCHARIDES CONJUGATED TO CORYNEBACTERIUM DIPHTHERIAE C7 (ß197) M8 (CRM197) PROTEIN[2] Corynebacterium diphtheriae (Synonym: Tetanus and Diphtheria Toxoids Adsorbed),
Corynebacterium diphtheriae CRM197 protein (Synonym: Diphtheria toxin mutant CRM197)
---[1] 11
185MENINGOCOCCAL GROUP Y OLIGOSACCHARIDES CONJUGATED TO CORYNEBACTERIUM DIPHTHERIAE C7 (Â197) M8 (CRM197) PROTEIN[2] Corynebacterium diphtheriae (Synonym: Tetanus and Diphtheria Toxoids Adsorbed),
Corynebacterium diphtheriae CRM197 protein (Synonym: Diphtheria toxin mutant CRM197)
---[1] 11
186METRONIDAZOLE
(Synonym: METRONIDAZOLE TOPICAL GEL)
[1] Metronidazole (Synonym: Metronidazole Topical Gel)[3] D00409 (Name: METRONIDAZOLE TOPICAL GEL),
D05016 ,
D05017
--[8] 46, 51, 63, 94, 95, 96, 97, 291
187Metronidazole capsule 50 mg
(Synonym: METRONIDAZOLE TOPICAL GEL)
[1] Metronidazole (Synonym: Metronidazole Topical Gel)[3] D00409 (Name: METRONIDAZOLE TOPICAL GEL),
D05016 ,
D05017
--[1] 97
188Metronidazole Oral
(Synonym: METRONIDAZOLE TOPICAL GEL)
[1] Metronidazole (Synonym: Metronidazole Topical Gel)[3] D00409 (Name: METRONIDAZOLE TOPICAL GEL),
D05016 ,
D05017
--[1] 96
189Midodrine or atomoxetine pill
(Synonym: Tomoxetine)
[2] Atomoxetine (Synonym: Tomoxetina),
Midodrine
[4] D01307 ,
D02574 (Name: Tomoxetine hydrochloride),
D07473 (Name: Tomoxetine),
D08220
[4] ADRA1A,
ADRA1B,
ADRA1D,
SLC6A2 💬
[8] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Synaptic vesicle cycle, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 17
190Mobilization of stem cells to prepare for Leukapheresis----[1] 96
191Modified Oral Glucose Tolerance Test (50g 4-hours)[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 299
192Most recent vaccine to seasonal influenza----[1] 13
193MRA (Tocilizumab)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
194MRA(Tocilizumab)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
195MSC2430913A or ONO-4641 (to be used as synonyms)----[1] 13
196MSC_NTF cells transplantation by multiple intramuscular injections at 24 separate sites, in addition to a single intrathechal injection into the CSF----[1] 2
197Multiple (4 autologous subcutaneous T cell vaccinations with T cell lines reactive to nine myelin peptides)----[1] 13
198N. MENINGITIDIS GROUP C (STRAIN C11) OLIGOSACCHARIDE CONJUGATED TO----[1] 11
199N. MENINGITIDIS GROUP C (STRAIN C11) OLIGOSACCHARIDE CONJUGATED TO CORYNEBACTERIUM DIPHTHERIAE CRM197 ADSORBED ON ALUMINUM HYDROXIDE[5] Aluminium,
Aluminum hydroxide (Synonym: Topcare Antacid Regular Strength),
Corynebacterium diphtheriae (Synonym: Tetanus and Diphtheria Toxoids Adsorbed),
Corynebacterium diphtheriae CRM197 protein (Synonym: Diphtheria toxin mutant CRM197),
Hydroxide ion
[1] D02416 --[1] 11
200Nebcin (tobramycin)[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
201Nebcinal Tobi----[1] 299
202Nebulization tobramycin[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
203NEISSERIA MENINGITIDIS GROUP A POLYSACCHARIDE CONJUGATED WITH TETANUS TOXOID CARRIER PROTEIN[1] Clostridium tetani toxoid antigen (formaldehyde inactivated)---[1] 50
204NEISSERIA MENINGITIDIS GROUP W-135 POLYSACCHARIDE CONJUGATED TO TETA[1] Triethylenetetramine---[1] 50
205NEISSERIA MENINGITIDIS GROUP W-135 POLYSACCHARIDE CONJUGATED TO TETANUS TOXOID CARRIER PROTEIN[1] Clostridium tetani toxoid antigen (formaldehyde inactivated)---[1] 50
206Nexavar (BAY 43-9006) (Sorafenib)
(Synonym: Sorafenib tosylate)
[1] Sorafenib[2] D06272 (Name: Sorafenib tosylate),
D08524
[8] BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬
[89] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 34
207Novel Allergen-Specific Immune Signature Directed Approach to Dietary Elimination Therapy----[1] 98
208Onabotulinum Toxin A----[1] 226
209OPC-41061 (tolvaptan)[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
210Open Label Topical Beremagene Geperpavec (B-VEC)----[1] 36
211Optical coherence tomography (OCT)----[1] 13
212Optical coherence tomography angiography (OCTA)----[1] 13
213Oral 5-ASA+/-topical 5-ASA+IV corticosteroids / PO Methylprednisolone[2] Mesalazine,
Methylprednisolone
[7] D00377 ,
D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002
[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
214Oral Glucose Tolerance Test[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 299
215Oral Glucose Tolerance test (75g 2-hour)[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 299
216OSU 6162 similar to (-)-OSU 6162----[1] 6
217OSU6162 similar to (-)-OSU 6162----[2] 6, 8
218Other: Acute response to high-impact exercise----[1] 96
219Other: BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (arterial blood gas and metabolic panel) and data collection from PSG study.----[1] 230
220Other: BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (venous blood gas and metabolic panel) and data collection from PSG study.----[1] 230
221Other: Diagnostics for glucose tolerance with 3 different methods.[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 299
222Other: Dose reduction to 2mg/L----[1] 46
223Other: Dose reduction to 5mg/L----[1] 46
224Other: Eating Assessment Tool 10----[1] 2
225Other: Eating Assessment Tool-10----[1] 2
226Other: Exposure to methylprednisolone during pregnancy[1] Methylprednisolone[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002
[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 13
227Other: glucose solution at a dose of 1.75 g/kg (up to a maximum of 75 g) for the OGTT and glucose solution at a dose of 0.5 g/kg (up to a maximum of 35 g) was injected in 2.5-3 min for the IGTT[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 299
228Other: High resolution peripheral quantitative computed tomography (HRpQCT)----[1] 172
229Other: Mixed Meal Tolerance Test----[1] 299
230Other: Modified Mixed Meal Tolerance Test----[1] 65
231Other: Modified Oral Glucose Tolerance Test[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 65
232Other: Oral Glucose tolerance test[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[3] 160, 195, 299
233Other: Oral Glucose Tolerance Test (OGTT) assessment arm[1] Dextrose, unspecified form (Synonym: 50gm Glucose Tolerance Drink)---[1] 299
234Other: Other biological samples to biobank (skin, lung and muscle biopsies----[3] 49, 51, 85
235Other: Recommendation with regard to nutrition----[1] 6
236Other: Refered to general practice----[1] 46
237Other: Screening to prevent falls----[1] 6
238Other: Squat-to-stand maneuver----[1] 58
239Other: Standard treatment according to the Clinical protocols----[3] 49, 51, 235
240Other: Standardized scales: MDS-UPDRS (Part II to IV) and RDRS----[1] 6
241Other: The patients' parents have to complete the VINELAND II adaptive behavior scales scoring, The Sleep Disturbance Scale for Children (SDSC) and Horne & Ostberg Circadian Typology Questionnaire----[1] 149
242Other: Tobacco questionnaire[1] Tobacco leaf---[1] 299
243Other: Tobramycin time of administration[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
244Outer membrane vesicles (OMV) from Neisseria meningitidis group B strain NZ98/254measured as amount of total protein containing the PorA P1.4----[1] 11
245Oxybutynin, tolterodine, solifenacin[3] Oxybutynin,
Solifenacin,
Tolterodine
[6] D00465 ,
D00646 (Name: Tolterodine),
D00722 ,
D01148 (Name: Tolterodine tartrate),
D01269 ,
D08522
[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 53
246Oxymizer® compared to CNC----[1] 85
247Patients will be randomized to receive EHP-101----[1] 51
248Pertussis toxoid[1] Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)---[1] 46
249PERTUSSIS TOXOID ADSORBED ON ALUMINIUM HYDROXIDE[4] Aluminium,
Aluminum hydroxide (Synonym: Topcare Antacid Regular Strength),
Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated),
Hydroxide ion
[1] D02416 --[1] 46
250Phase A Tolvaptan[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
251Phase B Tolvaptan[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
252Phentermine-Topiramate[2] Phentermine,
Topiramate
[3] D00537 (Name: Topiramate),
D05458 ,
D05459
[41] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
MAOA,
MAOB,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A,
SLC6A2,
SLC6A3,
SLC6A4 💬
[63] Adrenergic signaling in cardiomyocytes, Alcoholism, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arginine and proline metabolism, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, Drug metabolism - cytochrome P450, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, Glycine, serine and threonine metabolism, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Histidine metabolism, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Phenylalanine metabolism, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Synaptic vesicle cycle, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Tryptophan metabolism, Type II diabetes mellitus, Tyrosine metabolism, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 97
253PLA + MTX switched to ABA+ MTX, DB----[1] 46
254PNEUMOCOCCAL POLYSACCHARIDE CONJUGATE VACCINE (13-VALENT, ADSORBED) CONJUGATED TO CRM197 CARRIER PROTEIN AND ADSORBED ON ALUMINIUM PHOSPHATE[4] Aluminium,
Aluminium phosphate,
Corynebacterium diphtheriae CRM197 protein (Synonym: Diphtheria toxin mutant CRM197),
Phosphate ion
---[1] 46
255Positron Emission Tomography----[4] 40, 46, 49, 96
256Positron Emission Tomography using [11 Carbon]-3-amino-4-(2-dimethylaminomethylphenylsulfanyl)-benzonitrile ([11C]-DASB) and [18 Fluorine]-altanserin ([18F]-altanserin)[1] Activated charcoal---[1] 6
257Positron Emission Tomography using [18 Fluorine]-altanserin ([18F]-altanserin)----[1] 6
258Previously referred to as MEDI2070 and AMG 139----[2] 96, 97
259Previously referred to as MEDI2070 and AMG 139, AGN-151-598----[1] 96
260Primus FGTI (Flexible Great toe Implant)[1] Florasulam---[1] 46
261PXT3003 Dose 2 (equivalent to twice Dose 1)----[1] 10
262QR-313 Gel for Topical (Cutaneous) Administration----[1] 36
263Radiation: Computed tomography lung subtraction iodine mapping[1] Iodine (Synonym: Swiss Total One)[1] D00108 --[1] 88
264Radiation: Computerized Tomography scan----[1] 98
265Radiation: Cone Beam Computed Tomography (CBCT)[1] Tricyclazole---[1] 51
266Radiation: Irradiation, Total Body----[1] 274
267Radiation: low-dose total body irradiation (TBI)----[1] 60
268Radiation: PET (Positron Emission Tomography) Study----[1] 17
269Radiation: Single Photon Emission Computed Tomography scans----[1] 98
270Radiation: Total body 200cGy----[1] 65
271Radiation: Total Body Irradiation----[7] 36, 49, 51, 60, 65, 283, 284
272Radiation: Total Body Irradiation (TBI)----[3] 60, 65, 285
273Radiation: Total Body Irradiation 1200 cGy----[1] 60
274Radiation: Total Body Irradiation 200 cGy----[1] 60
275Radiation: Total Body Irradiation with Marrow Boosting----[2] 19, 234
276Radiation: Total Lymphoid Irradiation----[1] 326
277Radiation: Total Lymphoid Irradiation (TLI)----[1] 60
278Radiation: total-body irradiation----[9] 28, 51, 60, 62, 65, 96, 283, 284, 285
279Rapamycin cream, topical, 0.5%, 1.0% w/w[1] Sirolimus[1] D00753 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[1] 158
280RECOMBINANT HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 FUSED TO THE FC FRAGMENT OF IGG1----[1] 166
281Recombinant human monoclonal antibody to human IL-1Beta of the IgG1/K class----[3] 106, 107, 108
282Recombinant human monoclonal antibody to Il-17 of the IgG1-k-class----[1] 271
283Recombinant human monoclonal antibody to inerleukin-1beta of the IgG1-K-class----[1] 46
284Recombinant human monoclonal antibody to interleukin-1beta of the IgG1-Kappa-class----[1] 46
285RECOMBINANT HUMAN SERUM ALBUMIN (HSA) FUSED TO HUMAN GROWTH HORMONE (HGH)[2] Albumin human,
Somatotropin
[3] D02691 ,
D02792 ,
D05424
[1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 78
286Recombinant humanized monoclonal antibody omalizumab to IgE[1] Omalizumab[1] D05251 [1] FCER1A 💬[4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[1] 299
287Reduced Toxicity Ablative Regimen----[3] 62, 65, 284
288Response to anakinra associated with methotrexate[2] Anakinra,
Methotrexate
[3] D00142 ,
D02115 ,
D02934
[4] DHFR,
DHFR2,
IL1R1,
IL1R2 💬
[20] Amoebiasis, Antifolate resistance, Biosynthesis of cofactors, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Folate biosynthesis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Metabolic pathways, NF-kappa B signaling pathway, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[1] 46
289Response to infliximab associated with methotrexate[2] Infliximab,
Methotrexate
[3] D00142 ,
D02115 ,
D02598
[3] DHFR,
DHFR2,
TNF 💬
[71] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
290RhumAb to Il-17A (IgG1-k-class)----[4] 13, 46, 56, 96
291RhumAb to Il-17A (IgG1-k-class) rhumAb to Il-17A (IgG1-k-class)----[1] 96
292RhumAb to IL-17A igG1-k-class----[1] 13
293RoActemra/Actemra (tocilizumab)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 107
294RPC1063 (equivalent to ozanimod[1] Ozanimod[1] D10968 [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬
[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 96
295RPC1063 (equivalent to ozanimod HCl)[1] Ozanimod[1] D10968 [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬
[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 96
296RPC1063 equiv to ozanimod HCI[1] Ozanimod[1] D10968 [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬
[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 96
297RPC1063 equiv. to ozanimod HCI[1] Ozanimod[1] D10968 [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬
[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 96
298SB2 (proposed biosimilar to infliximab)[1] Infliximab[1] D02598 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
299SB4 (proposed biosimilar to etanercept)[1] Etanercept[1] D00742 [2] LTA,
TNF 💬
[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
300SB5 (proposed biosimilar to adalimumab)[1] Adalimumab[1] D02597 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
301Single Photon Emission Computed Tomography----[1] 34
302Sonic toothbrush----[1] 51
303Sonic toothbrush (Philips Sonicare) and water flosser (Philips Sonicare AirFloss)[1] Water (Synonym: Yumaki Original Mint Tooth)[1] D00001 --[1] 51
304Sorafenib
(Synonym: Sorafenib tosylate)
[1] Sorafenib[2] D06272 (Name: Sorafenib tosylate),
D08524
[8] BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬
[89] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[2] 34, 86
305Sorafenib (as tosylate)[1] Sorafenib[2] D06272 (Name: Sorafenib tosylate),
D08524
[8] BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬
[89] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 34
306Spinal anesthesia with tourniquet----[1] 46
307Spinal anesthesia without tourniquet----[1] 46
308Subcutaneous tocilizumab[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
309Subcutaneous tocilizumab 162mg/biweekly[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
310Suplatast tosilate----[1] 226
311Surgery to implant human CNS stem cells (HuCNS-SC)----[1] 19
312Switch to Myfortic[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬
[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 49
313Takecab tablets + amoxicillin + clarithromycin (first-line eradication) Takecab tablets + amoxicillin + metronidazole (second-line eradication)
(Synonym: METRONIDAZOLE TOPICAL GEL)
[3] Amoxicillin,
Clarithromycin,
Metronidazole (Synonym: Metronidazole Topical Gel)
[7] D00229 ,
D00276 ,
D00409 (Name: METRONIDAZOLE TOPICAL GEL),
D02925 ,
D05016 ,
D05017 ,
D07452
--[1] 63
314TC-A PS Total Knee Replacement System----[1] 46
315TC-PLUS Solution PS Total Knee Replacement System----[1] 46
316Tedizolid
(Synonym: Torezolid)
[1] Tedizolid (Synonym: Torezolid)[1] D09685 (Name: Torezolid)--[1] 299
317Tedizolid IV
(Synonym: Torezolid)
[1] Tedizolid (Synonym: Torezolid)[1] D09685 (Name: Torezolid)--[1] 299
318Tedizolid PO
(Synonym: Torezolid)
[1] Tedizolid (Synonym: Torezolid)[1] D09685 (Name: Torezolid)--[1] 299
319Temsirolimus
(Synonym: Torisel (TN))
[1] Temsirolimus (Synonym: Torisel)[1] D06068 (Name: Torisel (TN))[1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[4] 13, 34, 89, 331
320Temsirolimus Tablets
(Synonym: Torisel (TN))
[1] Temsirolimus (Synonym: Torisel)[1] D06068 (Name: Torisel (TN))[1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[1] 13
321Teriparatide conjugated to a multiarm polyethylene glycol carrier molecule through a cleava[2] Polyethylene glycol (Synonym: Topcare ClearLax),
Teriparatide
[2] D03370 ,
D06078
[1] PTH1R 💬[3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[1] 235
322Teriparatide conjugated to a multiarm polyethylene glycol carrier molecule through a cleavable linker[2] Polyethylene glycol (Synonym: Topcare ClearLax),
Teriparatide
[2] D03370 ,
D06078
[1] PTH1R 💬[3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[1] 235
323Tetanus diphtheria toxoid vaccine (Td)[1] Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)---[1] 13
324Tetanus diphtheria toxoids vaccine----[1] 13
325Tetanus toxoid[1] Clostridium tetani toxoid antigen (formaldehyde inactivated)---[4] 13, 14, 46, 50
326Tetanus toxoid (TT) containing vaccine (Td, Tdap)[1] Clostridium tetani toxoid antigen (formaldehyde inactivated)---[1] 13
327Tetanus toxoid adsorbed[1] Clostridium tetani toxoid antigen (formaldehyde inactivated)---[1] 46
328Tetanus toxoid adsorbed booster vaccine[1] Clostridium tetani toxoid antigen (formaldehyde inactivated)---[1] 46
329Tetanus Toxoid Adsorbed Vaccine[1] Clostridium tetani toxoid antigen (formaldehyde inactivated)---[1] 46
330Tetanus toxoid vaccine[1] Clostridium tetani toxoid antigen (formaldehyde inactivated)---[1] 13
331Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed)[3] Clostridium tetani toxoid antigen (formaldehyde inactivated),
Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated),
Pertussis vaccine (Synonym: Diphtheria and Tetanus Toxoids With Pertussis Vaccine Adsorbed)
[1] D06514 --[1] 46
332The investigational medicinal product (IMP) will be labeled as PF-04236921 106 mg/vial, Clonal SC lyophilized form, which is equivalent to PF-04236921 Powder for Injection, 106 mg/vial as described in the enclosed CTA----[1] 96
333The investigational medicinal product (IMP) will be labeled as PF-04236921 106 mg/vial, Clonal SC lyophilized form, which is equivalent to PF-04236921 Powder for Injection, 106 mg/vial as described in the enclosed CTA.----[1] 96
334Time delay treatment of botulinum toxin----[1] 149
335TIP (Tobramycin inhalation powder)[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
336TIS (Tobramycin Inhalation Solution)[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
337TO----[1] 6
338To be added after EV code is available----[1] 19
339To be confirmed----[3] 46, 65, 97
340To be determined----[2] 96, 113
341To be requested----[2] 96, 97
342Tobacco[1] Tobacco leaf---[1] 299
343TOBI----[1] 299
344TOBI (tobramycin)[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
345TOBI 300 mg / 5 mL nebuliser solution[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
346TOBI 300 mg/5 ml Lösung für einen[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
347TOBI 300 mg/5 ml Lösung für einen Vernebler[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
348TOBI 300 mg/5 ml Nebuliser Solution[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
349TOBI 300 mg/5 ml solución para inhalación por nebulizador[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
350TOBI 300 mg/5 ml, solution pour inhalation par nébuliseur[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
351TOBI 300mg/ 5ml solución para inhalación con nebulizador[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
352TOBI 300mg/5mL Nebuliser Solution[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
353Tobi 300mg/5ml Nebuliser solution.[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
354Tobi 300mg/5ml Solución para inhalación por nebulizador.[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
355Tobi Inhalant Product[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
356Tobi Nebcinal----[1] 299
357TOBI PODHALER----[1] 299
358TOBI PODHALER - 28 MG POLVERE PER INALAZIONE CAPSULA RIGIDA USO INALATORIO BLISTER(ALU/ALU) 56 CAPSULE + 1 INALATORE[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
359TOBI Podhaler 28 mg Hartkapseln mit Pulver zur Inhalation[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
360TOBI Podhaler 28 mg inhalációs por, kemény kapszula[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
361TOBI PODHALER*448CPS 28MG+10IN[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
362TOBI*NEBUL 56F 1D 300MG/5ML[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
363TOBI®[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
364TOBI™ Podhaler™ 112 mg inhaled twice daily----[1] 299
365Tobramcyin----[1] 299
366TOBRAMICINA[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
367Tobramicina polvere inalatoria[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
368TOBRAMICINA SOLFATO[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
369Tobramicyn----[1] 299
370TOBRAMYCIN[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
371Tobramycin (Gernebcin®)[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
372Tobramycin / Bramitob[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
373Tobramycin / TOBI[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
374Tobramycin 100 PARI[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
375Tobramycin dry powder[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
376Tobramycin for Inhalation[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
377Tobramycin Inhalation Powder[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
378Tobramycin Inhalation Powder (TIP)[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
379Tobramycin Inhalation Powder TIP delivered by the T-326 Inhaler[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
380Tobramycin inhalation solution[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
381Tobramycin Inhalation Solution (TIS)[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
382Tobramycin inhalation solution using a PARI LC® Plus nebulizer.[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
383Tobramycin injection 40mg/1ml[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
384Tobramycin nebulized nasally[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
385Tobramycin Powder[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
386Tobramycin Solution for Inhalation[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
387Tobramycin solution for inhalation (TOBI)[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
388Tobramycin solution for inhalation 300 mg[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
389Tobramycin Steri-Neb 300 mg/5 ml, inhalation solution[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
390TOBRAMYCIN SULFATE[2] Sulfate ion,
Tobramycin
[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
391Tobramycine[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
392Tobramycinum[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
393Tobrineb/Bramitob----[1] 299
394Tocilizumab[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
395Tocilizumab (Actemra or RoActemra)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
396Tocilizumab (Actemra)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
397Tocilizumab (Actemra®)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
398Tocilizumab (MRA-SC)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 40
399Tocilizumab (TCZ)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 56
400Tocilizumab + Glucocorticoids (GCs)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
401Tocilizumab + methotrexate(MTX)[2] Methotrexate,
Tocilizumab
[3] D00142 ,
D02115 ,
D02596 (Name: Tocilizumab)
[3] DHFR,
DHFR2,
IL6R 💬
[17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
402Tocilizumab 162 mg[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
403Tocilizumab 162mg/0.9ml jeringa SC[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
404Tocilizumab 162mg/0.9ml SC PFS SC[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
405Tocilizumab 162mg/0.9ml syringe SC[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
406Tocilizumab [RoActemra/Actemra][1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[4] 46, 51, 107, 331
407Tocilizumab [RoActemra][1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
408Tocilizumab and IV steroids combination[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
409Tocilizumab Infusion RoAcemtra (EU)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 266
410Tocilizumab Injectable Product[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 11
411Tocilizumab Injection[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 13
412Tocilizumab Injection 8mg/kg[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
413Tocilizumab IV[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
414Tocilizumab plus methotrexate[2] Methotrexate,
Tocilizumab
[3] D00142 ,
D02115 ,
D02596 (Name: Tocilizumab)
[3] DHFR,
DHFR2,
IL6R 💬
[17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
415Tocilizumab Prefilled Syringe[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 41, 46
416Tocilizumab Roche[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 46, 107
417TOCILIZUMAB SC[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[3] 41, 46, 107
418Tocilizumab SC 162 mg/0.9 ml disposable auto-injector (AI)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
419Tocilizumab SC 162 mg/0.9 ml pre-filled syringe with safety device (PFS)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
420Tocilizumab SC 162 mg/0.9 ml prefilled syringe with safety device (PFS)[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 51
421Tocilizumab treatment[1] Tocilizumab[1] D02596 (Name: Tocilizumab)[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
422Tocilizumab+Methotrexate(MTX)[2] Methotrexate,
Tocilizumab
[3] D00142 ,
D02115 ,
D02596 (Name: Tocilizumab)
[3] DHFR,
DHFR2,
IL6R 💬
[17] Antifolate resistance, Biosynthesis of cofactors, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Folate biosynthesis, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Metabolic pathways, Non-alcoholic fatty liver disease, One carbon pool by folate, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
423Tocilizumab, Abatacept[2] Abatacept,
Tocilizumab
[2] D02596 (Name: Tocilizumab),
D03203
[3] CD80,
CD86,
IL6R 💬
[24] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Rheumatoid arthritis, Systemic lupus erythematosus, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
424Tocilizumabum----[1] 46
425Tocoferol[1] Tocopherol[1] D02332 (Name: Tocopherol)--[1] 90
426Tocopherol[1] Tocopherol[1] D02332 (Name: Tocopherol)--[5] 13, 49, 206, 257, 298
427Tocopherol (vit E)[1] Tocopherol[1] D02332 (Name: Tocopherol)--[1] 257
428Tocopherol acetate[3] Acetate,
Tocopherol,
alpha-Tocopherol acetate
[1] D02332 (Name: Tocopherol)--[1] 49
429TOCOPHERYL ACETATE[2] Acetate,
alpha-Tocopherol acetate
---[1] 206
430Tocotrienol[1] Tocotrienol---[3] 21, 156, 299
431Tocotrienols----[1] 2
432Tocovid Suprabio (HOV-12020)----[1] 6
433Toctino[1] Alitretinoin (Synonym: Toctino)[1] D02815 [5] RARA,
RARB,
RXRA,
RXRB,
RXRG 💬
[19] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[1] 49
434Toctino®[1] Alitretinoin (Synonym: Toctino)[1] D02815 [5] RARA,
RARB,
RXRA,
RXRB,
RXRG 💬
[19] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[1] 49
435TOF repair with trans-annular patch VS preservation of PV----[1] 215
436TOFACINITIB----[1] 97
437Tofacitinb----[1] 46
438Tofacitinib[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
439Tofacitinib (CP-690,550)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 96
440Tofacitinib (Xeljanz)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
441Tofacitinib (Xeljanz®)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
442Tofacitinib (Xeljanz®) 11mg Prolonged Release Tablet[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
443Tofacitinib 10 mg[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 271
444Tofacitinib 10 MG [Xeljanz][1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 97
445Tofacitinib 2 mg[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 271
446Tofacitinib 5 MG[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[5] 11, 40, 46, 256, 271
447Tofacitinib 5 MG [Xeljanz][1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[2] 46, 50
448Tofacitinib 5 mg twice daily[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 84
449Tofacitinib 5mg [Xeljanz] 1 year open-label extension[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 84
450Tofacitinib 5mg Oral Tablet [Xeljanz] 16 week trial[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 84
451Tofacitinib 5mg po bid[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
452Tofacitinib citate (Phase III formulation)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
453TOFACITINIB CITRATE[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[5] 46, 49, 97, 107, 271
454Tofacitinib citrate (clinical trial image)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[2] 46, 97
455Tofacitinib citrate (commercial image)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
456Tofacitinib citrate (Phase III formulation)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[2] 46, 97
457Tofacitinib citrate (Proposed commercial formulation - debossed)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[2] 46, 97
458Tofacitinib citrate (Proposed commercial formulation debossed)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
459Tofacitinib citrate (Proposed commercial formulation – debossed)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[2] 46, 97
460Tofacitinib citrate (Proposed commercial formulation- debossed)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
461Tofacitinib citrate (Proposed commercialFormulation - debossed)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 97
462TOFACITINIB CITRATE CP-690550[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
463Tofacitinib citrate( Phase III formulation)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
464Tofacitinib or Baricitinib[2] Baricitinib,
Tofacitinib
[2] D09970 (Name: Tofacitinib),
D10308
[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
465Tofacitinib tablet[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 40
466Tofacitinib with methotrexate[2] Methotrexate,
Tofacitinib
[3] D00142 ,
D02115 ,
D09970 (Name: Tofacitinib)
[6] DHFR,
DHFR2,
JAK1,
JAK2,
JAK3,
TYK2 💬
[42] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Antifolate resistance, Biosynthesis of cofactors, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Folate biosynthesis, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, Metabolic pathways, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, One carbon pool by folate, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
467Tofacitinib without methotrexate[2] Methotrexate,
Tofacitinib
[3] D00142 ,
D02115 ,
D09970 (Name: Tofacitinib)
[6] DHFR,
DHFR2,
JAK1,
JAK2,
JAK3,
TYK2 💬
[42] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Antifolate resistance, Biosynthesis of cofactors, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Folate biosynthesis, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, Metabolic pathways, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, One carbon pool by folate, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
468Tofacitinib XR[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[2] 46, 271
469Tofacitinib/baricitinib[2] Baricitinib,
Tofacitinib
[2] D09970 (Name: Tofacitinib),
D10308
[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 46
470Tofacitinibe citrate----[1] 107
471Tofersen[1] Tofersen[1] D11811 (Name: Tofersen)[1] SOD1 💬[8] Amyotrophic lateral sclerosis, Chemical carcinogenesis - reactive oxygen species, Huntington disease, Longevity regulating pathway - multiple species, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Peroxisome, Prion disease 💬[1] 2
472TOL----[1] 67
473TolaSure Topical Gel----[1] 36
474Tolcapon[1] Tolcapone[1] D00786 (Name: Tolcapone)[1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6
475TOLCAPONE[1] Tolcapone[1] D00786 (Name: Tolcapone)[1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[3] 6, 28, 127
476TolDC----[1] 46
477Tolebrutinib----[2] 11, 13
478Tolebrutinib 120mg----[1] 13
479Tolebrutinib 60mg----[1] 13
480Tolebrutininb----[1] 11
481Tolerogenic dendritic cells----[2] 46, 96
482Tolerogenic dendritic cells (tolDC)----[1] 13
483Tolerogenic Dendritic cells loaded with myelin peptides----[1] 13
484Tolerogenic Fibroblasts----[1] 13
485Tolfenamic Acid[1] Tolfenamic acid[1] D01183 (Name: Tolfenamic acid)[2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 5
486Tolicizumab----[1] 46
487Tolicizumab Roche----[1] 46
488Tolperisone[1] Tolperisone[1] D08617 (Name: Tolperisone)--[1] 13
489Tolperisone HC1[1] Tolperisone[1] D08617 (Name: Tolperisone)--[1] 13
490Tolperisone HCl[1] Tolperisone[1] D08617 (Name: Tolperisone)--[1] 13
491Tolpersan----[1] 13
492Tolposan----[1] 13
493Tolterodine[1] Tolterodine[2] D00646 (Name: Tolterodine),
D01148 (Name: Tolterodine tartrate)
[1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 17, 53
494Tolubuterol Hydrochloride----[1] 6
495TOLVAPTAN[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[3] 67, 72, 225
496TOLVAPTAN (OPC-41061)[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
497Tolvaptan (SAMSCA)[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 72
498TOLVAPTAN 15[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
499Tolvaptan 15 mg Tablet[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
500Tolvaptan 15 mg tablets[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
501Tolvaptan 15mg[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
502TOLVAPTAN 30[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
503Tolvaptan 30 mg Tablet[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
504Tolvaptan 30 mg tablets[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
505Tolvaptan 30mg[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
506TOLVAPTAN 45/15[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
507Tolvaptan 50mg Granules[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
508TOLVAPTAN 60/30[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
509Tolvaptan 7.5 mg Tablet[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
510Tolvaptan in euvolemic hyponatremia[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 72
511Tolvaptan IR[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
512Tolvaptan MR[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
513Tolvaptan Oral Tablet[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 72
514Tolvaptan Suspension[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
515Tolvaptan Tablets[1] Tolvaptan[1] D01213 (Name: Tolvaptan)[1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 67
516Tominersen----[1] 8
517Top-down----[1] 96
518TOP1288----[1] 97
519TOP1288 Rectal solution----[1] 97
520TOPAMAX[1] Topiramate[1] D00537 (Name: Topiramate)[36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 140
521Topical 0.1% Sirolimus[1] Sirolimus[1] D00753 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[1] 278
522Topical AmphiMatrix----[1] 51
523Topical AmphiMatrix with nitroglycerin (MQX-503)[1] Nitroglycerin[1] D00515 --[1] 51
524Topical Beremagene Geperpavec----[1] 36
525Topical BPM31510 3.0% Cream----[1] 36
526Topical calcipotriene 0.005% ointment[1] Calcipotriol (Synonym: Dovonex Solution - Top 50mcg/ml)[1] D01125 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 51
527Topical compound tripterygium[1] Tripterygium wilfordii whole---[1] 46
528Topical infliximab[1] Infliximab[1] D02598 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[3] 38, 39, 162
529Topical opiod----[1] 36
530Topical organogel with nitroglycerin[1] Nitroglycerin[1] D00515 --[1] 51
531Topical Pentoxifylline Gel (Vehicle +PTX)[1] Pentoxifylline[1] D00501 --[1] 56
532Topical Preparation H arm----[1] 13
533Topical timolol maleate[1] Timolol[3] D00378 ,
D00603 ,
D08600
[2] ADRB1,
ADRB2 💬
[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 227
534Topical tripterygium gel[1] Tripterygium wilfordii whole---[1] 46
535Topical Vehicle----[1] 278
536Topimarate----[1] 144
537Topimarato----[1] 144
538TOPIRAMATE[1] Topiramate[1] D00537 (Name: Topiramate)[36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193
539Topiramate (drug)[1] Topiramate[1] D00537 (Name: Topiramate)[36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6
540Topotecan[1] Topotecan[2] D02168 (Name: Topotecan hydrochloride),
D08618 (Name: Topotecan)
[1] TOP1 💬-[1] 25
541Torvast----[1] 13
542TORVAST*10CPR 10MG----[1] 13
543Total body Irradiation----[6] 19, 20, 51, 60, 65, 285
544Total Body Irradiation (TBI) (Plan 1)----[2] 60, 285
545Total Dietary Replacement----[1] 265
546Total Glucosides Paeony Capsules----[1] 271
547Total hip arthoplasty (THA)----[1] 46
548Total hip arthroplasty (Fitmore or CLS uncemented femoral stem made by Zimmer-Biomet, Warshaw, USA)----[1] 71
549Total lymphoid irradiation----[3] 65, 284, 326
550Total thyroidectomy----[1] 235
551Total-Body Irradiation----[1] 51
552TOTTIZIM - 1 G/10 ML POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE PER USO ENDOVENOSO 1 FLACONCINO POLVERE + 1 FIALA SOLVENTE 10 ML----[1] 299
553Tovaxin----[1] 13
554Tovaxin Autologous T Cell Vaccine----[1] 13
555Toxicity, Pharmacokinetics----[1] 34
556TOZ----[1] 6
557TOZADENANT[1] Tozadenant[1] D10174 (Name: Tozadenant)[1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6
558Tozadenant (SYN115) 120 mg BID[1] Tozadenant[1] D10174 (Name: Tozadenant)[1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6
559Tozadenant (SYN115) 180 mg BID[1] Tozadenant[1] D10174 (Name: Tozadenant)[1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6
560Tozadenant (SYN115) 240 mg BID[1] Tozadenant[1] D10174 (Name: Tozadenant)[1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6
561Tozadenant (SYN115) 60 mg BID[1] Tozadenant[1] D10174 (Name: Tozadenant)[1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6
562Tozinameran[1] Pfizer-BioNTech COVID-19 Vaccine (Synonym: Tozinameran)[1] D11971 (Name: Tozinameran)--[1] 299
563Treat to target----[1] 46
564Treatment according to current standards without knowledge of serum infliximab and anti-infliximab Ab status[1] Infliximab[1] D02598 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 96
565Treatment with topical superpotent corticosteroid therapy----[1] 162
566Untreated to atorvastatin treatment[1] Atorvastatin[3] D00258 ,
D00887 ,
D07474
[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 13
567Urine samples taken to measure methotrexate and its major metabolite 7-OH-methotrexate level[1] Methotrexate[2] D00142 ,
D02115
[2] DHFR,
DHFR2 💬
[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 46
568Ursodeoxycholic acid combined with total glucosides of paeony[1] Ursodeoxycholic acid (Synonym: BAMBOO SALT Eunganggo Jook Yeom Toothpaste)[1] D00734 [1] NR1H4 💬[1] Bile secretion 💬[1] 93
569Use of an Electronic Data Capture System by patients and physicians to assess patient-physician interactions & therapeutic decisions & outcomes in RA subjects.[1] Bifenthrin---[1] 46
570Use of bioanalytical assay to monitor plasma levels of perhexiline[2] Methamidophos,
Perhexiline
[2] D05442 ,
D08340
[8] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CPT1A,
CPT1B,
CPT1C,
CPT2 💬
[47] AMPK signaling pathway, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Dopaminergic synapse, Fatty acid degradation, Fatty acid metabolism, GABAergic synapse, Glucagon signaling pathway, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin resistance, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, PPAR signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Thermogenesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 58
571VACCINO HAEMOPHILUS INFLUENZAE B CONIUGATO CON TOSSOIDETETANICO----[2] 61, 62
572Vantobra (tobramycin)[1] Tobramycin[2] D00063 (Name: Tobramycin),
D02542 (Name: Tobramycin sulfate)
--[1] 299
573Vedolizumab, Ustekinumab, or Tofacitinib[3] Tofacitinib,
Ustekinumab,
Vedolizumab
[3] D08083 ,
D09214 ,
D09970 (Name: Tofacitinib)
[9] IL12A,
IL12B,
IL23A,
ITGA4,
ITGB7,
JAK1,
JAK2,
JAK3,
TYK2 💬
[65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, Arrhythmogenic right ventricular cardiomyopathy, C-type lectin receptor signaling pathway, Cell adhesion molecules, Chagas disease, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, ECM-receptor interaction, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Focal adhesion, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pertussis, Primary immunodeficiency, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Yersinia infection 💬[1] 97
574Vehicle of ADX-102 Topical Dermal Cream----[1] 160
575Vehicle Topical Gel----[1] 36
576Warm compress prior to injection of glatiramer acetate[2] Acetate,
Glatiramer
[1] D04318 [20] HLA-A,
HLA-B,
HLA-C,
HLA-DMA,
HLA-DMB,
HLA-DOA,
HLA-DOB,
HLA-DPA1,
HLA-DPB1,
HLA-DQA1,
HLA-DQA2,
HLA-DQB1,
HLA-DRA,
HLA-DRB1,
HLA-DRB3,
HLA-DRB4,
HLA-DRB5,
HLA-E,
HLA-F,
HLA-G 💬
[32] Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cellular senescence, Endocytosis, Epstein-Barr virus infection, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Phagosome, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis 💬[1] 13
577Wound topically irrigated with 500mg TXA----[1] 70
578XELJANZ (tofacitinib)[1] Tofacitinib[1] D09970 (Name: Tofacitinib)[4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 65
579ZX008 0.2 to 0.8 mg/kg/day----[2] 140, 144