Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Amitriptyline, fluoxetine and tramadol alone (control group)
(Synonym: D01355)		[3] Amitriptyline,
Fluoxetine,
Tramadol		[6] D00326 ,
D00809 ,
D00823 ,
D01355 ,
D07448 ,
D08623 		[3] OPRM1,
SLC6A2,
SLC6A4 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 78
2Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group)
(Synonym: D01355)		[4] Amitriptyline,
Fluoxetine,
Somatotropin,
Tramadol		[7] D00326 ,
D00809 ,
D00823 ,
D01355 ,
D02691 ,
D07448 ,
D08623 		[4] GHR,
OPRM1,
SLC6A2,
SLC6A4 💬		[9] Cytokine-cytokine receptor interaction, Estrogen signaling pathway, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 78
3Tramadol
(Synonym: D01355)		[1] Tramadol[2] D01355 ,
D08623 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271
4Tramadol /acetaminophen
(Synonym: D01355)		[2] Acetaminophen,
Tramadol		[3] D00217 ,
D01355 ,
D08623 		[3] OPRM1,
PTGS1,
PTGS2 💬		[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Estrogen signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 271
5Tramadol hydrochloride + acetaminophen
(Synonym: D01355)		[2] Acetaminophen,
Tramadol		[3] D00217 ,
D01355 ,
D08623 		[3] OPRM1,
PTGS1,
PTGS2 💬		[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Estrogen signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
6Tramadol with ropivacaine
(Synonym: D01355)		[2] Ropivacaine,
Tramadol		[4] D01355 ,
D04048 ,
D08490 ,
D08623 		[6] OPRM1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[6] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction 💬[1] 70