Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Amitriptyline
(Synonym: D07448)		[1] Amitriptyline[2] D00809 ,
D07448 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 78, 97, 226, 299
2Amitriptyline hydrochloride
(Synonym: D07448)		[1] Amitriptyline[2] D00809 ,
D07448 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 97
3Amitriptyline, fluoxetine and tramadol alone (control group)
(Synonym: D07448)		[3] Amitriptyline,
Fluoxetine,
Tramadol		[6] D00326 ,
D00809 ,
D00823 ,
D01355 ,
D07448 ,
D08623 		[3] OPRM1,
SLC6A2,
SLC6A4 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 78
4Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group)
(Synonym: D07448)		[4] Amitriptyline,
Fluoxetine,
Somatotropin,
Tramadol		[7] D00326 ,
D00809 ,
D00823 ,
D01355 ,
D02691 ,
D07448 ,
D08623 		[4] GHR,
OPRM1,
SLC6A2,
SLC6A4 💬		[9] Cytokine-cytokine receptor interaction, Estrogen signaling pathway, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 78