KEGG DRUG

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No.	DrugBank	Drug (Description in trials)	KEGG DRUG	KEGG GENES	KEGG PATHWAY	Disease ID
1	Diphenhydramine (Synonym: Sunmark Ibuprofen PM)	[2] Diphenhydramine; Diphenhydramine hydrochloride	[6] D00300 , D00669 , D02419 , D03285 , D03360 , D03854	[1] HRH1 💬	[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬	[10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
2	Famotidine (Synonym: Ibuprofen and famotidine)	[2] FAMOTIDINA; Famotidine	[1] D00318	[1] HRH2 💬	[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬	[7] 6, 46, 61, 86, 98, 107, 300
3	Ibuprofen	[2] Ibuprofen; IBUPROFEN 200MG	[4] D00126 (Name: Ibuprofen), D01122 (Name: Ibuprofen piconol), D04490 (Name: Ibuprofen aluminum), D06606 (Name: Ibuprofen lysine)	[2] PTGS1, PTGS2 💬	[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬	[7] 13, 46, 65, 107, 113, 271, 299
4	Oxycodone (Synonym: Oxycodone hydrochloride and Ibuprofen)	[3] OXYCODONE; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen	[3] D03783 , D05312 , D05462	[3] OPRD1, OPRK1, OPRM1 💬	[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬	[7] 6, 13, 46, 70, 226, 231, 298
5	Pseudoephedrine (Synonym: Good Neighbor Pharmacy Ibuprofen Cold and Sinus)	[1] Pseudoephedrine	[4] D00485 , D05648 , D05649 , D08449	[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬	[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬	[1] 17