Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Synonym: Acetaminophen/pseudoephedrine/dextromethorphan/doxylamine)		[5] Acetaminophen; Oxycodone/Acetaminophen; PARACETAMOL; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Cetirizine
(Synonym: Rugby Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride)		[3] Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE[2] D00664 ,
D07662 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 28, 35, 300
3 Chlorpheniramine
(Synonym: Hydrocodone Bitartrate Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride)		[1] Clorfenamina[4] D00665 ,
D00668 ,
D07398 ,
D07803 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
4 Dextromethorphan
(Synonym: Acetaminophen/pseudoephedrine/dextromethorphan/doxylamine)		[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta[3] D00848 ,
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
5 Fexofenadine
(Synonym: Fexofenadine Hydrochloride and Pseudoephedrine Hydrochloride)		[1] Fexofenadine[2] D00671 ,
D07958 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[2] 13, 46
6 Ibuprofen
(Synonym: Ibuprofen + Pseudoephedrine Caplets)		[2] IBUPROFEN; IBUPROFEN 200MG[4] D00126 ,
D01122 ,
D04490 ,
D06606 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299
7 Loratadine
(Synonym: Loratadine and Pseudoephedrine Sulfate)		[2] Loratadina; Loratadine[1] D00364 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 46, 89, 98
8 Pseudoephedrine [1] Pseudoephedrine[4] D00485 (Name: Pseudoephedrine hydrochloride),
D05648 (Name: Pseudoephedrine polistirex),
D05649 (Name: Pseudoephedrine sulfate),
D08449 (Name: Pseudoephedrine)		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17