Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Synonym: Mucinex Sinus-action Complete Congestion and Sinus Pain)		[5] Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Acetylsalicylic acid
(Synonym: Excedrin PM Triple Action Caplets)		[2] ACETYLSALICYLIC ACID; Aspirin[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251
3 Acteoside [1] Acteoside---[1] 66
4 Activated charcoal [1] Carbon---[9] 6, 46, 50, 51, 85, 86, 96, 97, 298
5 Adenosine
(Synonym: Incellderm Active Creamex)		[2] Adenosine; Ginseng[1] D00045 [4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		[12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 13, 58, 65
6 Alendronic acid
(Synonym: Act Alendronate)		[3] Alendronate; Alendronate sodium; Alendronic acid[2] D00939 ,
D07119 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299
7 Alginic acid
(Synonym: Tums Dual Action)		[3] Algin; Alginate; Alginic acid[1] D02324 --[4] 51, 53, 97, 299
8 Allantoin
(Synonym: Actifirm Recovery Eye Gowoonsesang Expert)		[1] ALLANTOIN[1] D00121 --[1] 36
9 Aloe vera leaf
(Synonym: Re-action E)		[3] Aloe; Aloe vera; Aloe vera gel---[3] 53, 97, 226
10 Aluminum hydroxide
(Synonym: Maximum Strength Fast Acting Antacid Anti-gas)		[2] Aluminium hydroxide; Aluminum hydroxide[1] D02416 --[2] 11, 46
11 Amlodipine
(Synonym: Act Amlodipine)		[1] Amlodipine[3] D00615 ,
D02914 ,
D07450 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 13, 51, 67, 298
12 Ammonium chloride
(Synonym: Ecopp Long Acting Antibacterial Disinfectant)		[1] Ammonium chloride[1] D01139 --[3] 96, 107, 251
13 Ascorbic acid
(Synonym: Acti-scorb 500 Caplet 500mg)		[4] Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C[1] D00018 --[8] 10, 97, 192, 206, 210, 211, 212, 298
14 Atacicept
(Synonym: Human Transmembrane Activator and CAML Interactor)		[2] ATACICEPT; TACI-Fc5[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[4] 13, 46, 49, 66
15 Atenolol
(Synonym: Act Atenolol)		[1] ATENOLOL[1] D00235 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167
16 Azithromycin
(Synonym: Act Azithromycin)		[5] Azithromycin; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax[3] D02134 ,
D06390 ,
D07486 		--[6] 13, 84, 85, 96, 228, 299
17 Beta carotene
(Synonym: Acti-retinol & Zn Caplet)		[3] Beta carotene; Beta-Carotene; BETACAROTENE[1] D03101 --[2] 13, 96
18 Bezafibrate
(Synonym: Act-bezafibrate SR)		[1] Bezafibrate[1] D01366 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[7] 20, 93, 94, 160, 296, 316, 324
19 Biotin
(Synonym: Bonogen Activator hair loss treatment)		[4] BIOTIN; Biotina; D-BIOTIN; Vitamin B7[1] D00029 --[5] 2, 8, 10, 13, 20
20 Bortezomib D-mannitol
(Synonym: Act Bortezomib)		[3] BORTEZOMIB; Bortezomib D-mannitol; VELCADE---[3] 11, 28, 61
21 Bosentan
(Synonym: Act Bosentan)		[2] BOSENTAN; TRACLEER[2] D01227 ,
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
22 Cabergoline
(Synonym: Act Cabergoline)		[3] CABERGOLINA; Cabergoline; DOSTINEX[1] D00987 [2] DRD2,
PRL 💬		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 75
23 Caffeine
(Synonym: Re-action E)		[1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 2, 6, 13, 21, 46, 78, 96, 97, 265
24 Calcium
(Synonym: ENA Actimineral A)		[2] Calcio; Calcium---[30] 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
25 Calcium carbonate
(Synonym: Up and Up dual action acid controller complete)		[3] Calcio carbonato; Calcium; Calcium carbonate[2] D00932 ,
D10802 		--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
26 Candesartan cilexetil
(Synonym: Act Candesartan/hct)		[1] CANDESARTAN[2] D00522 ,
D00626 		[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 67
27 Capsaicin
(Synonym: Parche Leon Milagroso Dual Action)		[2] Capsaicin; Qutenza[1] D00250 [1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[5] 2, 6, 19, 86, 226
28 Carboxymethylcellulose
(Synonym: Walgreens Dual Action Lubricant Eye)		[1] Carboxymethylcellulose[1] D07622 --[2] 35, 162
29 Celecoxib
(Synonym: Act Celecoxib)		[2] CELEBREX; Celecoxib[1] D00567 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
30 Cetirizine
(Synonym: Rx Act all day allergy relief)		[3] Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE[2] D00664 ,
D07662 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 28, 35, 300
31 Chlorpheniramine
(Synonym: Childrens Dimetapp Long Acting Cough Plus Cold)		[1] Clorfenamina[4] D00665 ,
D00668 ,
D07398 ,
D07803 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
32 Cholecalciferol
(Synonym: Active FE)		[5] Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[25] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
33 Chromium
(Synonym: Multi-actin)		[1] Chromium---[1] 46
34 Ciprofloxacin
(Synonym: Act Ciprofloxacin)		[2] CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE[2] D00186 ,
D02216 		--[5] 2, 60, 96, 97, 299
35 Citalopram
(Synonym: Act Citalopram)		[1] Citalopram[2] D00822 ,
D07704 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
36 Citric acid
(Synonym: bdr Re-action natural low base skin refiner exfoliation essence)		[1] Citric acid[2] D00037 ,
D01222 		--[2] 53, 291
37 Clarithromycin
(Synonym: Act Clarithromycin XL)		[1] Clarithromycin[1] D00276 --[8] 6, 63, 84, 96, 97, 222, 228, 299
38 Clopidogrel
(Synonym: Act Clopidogrel)		[1] Clopidogrel[4] D00769 ,
D07729 ,
D10823 ,
D10824 		[1] P2RY12 💬[1] Platelet activation 💬[2] 49, 86
39 Coagulation factor VIIa Recombinant Human [1] RFVIIa[1] D00172 (Name: Eptacog alfa (activated) (genetical recombination) (JAN))--[1] 288
40 Cobamamide
(Synonym: Acti-folic + Dibencozide Caplets)		[1] Cobamamide[1] D00042 --[1] 299
41 Copper
(Synonym: Actyform)		[2] Copper; Nicotinamide---[4] 2, 169, 170, 171
42 Corticorelin ovine triflutate
(Synonym: Acthrel)		[1] Acthrel[1] D03592 (Name: Acthrel (TN))[2] CRHR1,
CRHR2 💬		[4] Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 75
43 Corticotropin
(Synonym: Acthar Gel Hp Inj 40unit/ml)		[5] ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin[1] D00146 (Name: ACTH (TN))[1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[15] 2, 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222
44 Cyanocobalamin
(Synonym: Multi-actin)		[2] Cianocobalamina; Vitamin B12[4] D00166 ,
D03615 ,
D03616 ,
D03617 		--[5] 6, 13, 201, 229, 299
45 Desloratadine
(Synonym: Aerius Dual Action 24 Hour)		[1] Desloratadine[1] D03693 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 13
46 Dextran
(Synonym: Visine for Red Eye Triple Action)		[1] Dextran[1] D00060 --[5] 2, 62, 79, 96, 97
47 Dextromethorphan
(Synonym: Mucinex Multi-action Congestion & Cold Caplets)		[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta[3] D00848 ,
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
48 Diclofenac
(Synonym: Act Diclo-miso)		[3] Diclofenac; Diclofenac sodium; Diclofenac SR[3] D00903 ,
D00904 ,
D07816 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271
49 Diltiazem
(Synonym: Act Diltiazem CD)		[2] Diltiazem; Diltiazem Hydrochloride[3] D00616 ,
D03830 ,
D07845 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 58, 86
50 Diphenhydramine
(Synonym: Excedrin PM Triple Action Caplets and Excedrin Extra Strength Pain Reliever)		[2] Diphenhydramine; Diphenhydramine hydrochloride[6] D00300 ,
D00669 ,
D02419 ,
D03285 ,
D03360 ,
D03854 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[10] 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
51 Doconexent
(Synonym: Active OB)		[1] Docosahexaenoic acid---[10] 6, 46, 48, 49, 90, 94, 113, 240, 299, 301
52 Donepezil
(Synonym: Act Donepezil ODT)		[3] ARICEPT; Donepezil; Donepezil hydrochloride[2] D00670 ,
D07869 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
53 Dopamine [2] Dopamina; Dopamine[2] D00633 (Name: Actopamin (TN)),
D07870 		[5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 7, 74, 299
54 Dorzolamide
(Synonym: Act Dorzotimolol)		[1] Dorzolamide[2] D00653 ,
D07871 		[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90
55 Doxycycline
(Synonym: Acticlate CAP)		[4] Doxycyclin; DOXYCYCLINE; DOXYCYCLINE HYCLATE; Doxycycline Tablets[5] D00307 ,
D02129 (Name: ACTICLATE),
D03903 ,
D03904 ,
D07876 		--[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
56 Dutasteride
(Synonym: Act Dutasteride)		[2] Dutasterida; Dutasteride[1] D03820 [2] SRD5A1,
SRD5A2 💬		[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[2] 1, 2
57 Enalapril
(Synonym: Act Enalapril)		[2] Enalapril; Enalapril Maleate[2] D00621 ,
D07892 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222
58 Ephedrine
(Synonym: Bronkaid Dual Action Formula)		[2] Efedrina; Ephedrine[1] D00124 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 11
59 Ergocalciferol
(Synonym: Activated ergosterol)		[3] Ergocalciferol; Vitamin D; Vitamin D2[1] D00187 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[6] 46, 49, 84, 96, 97, 299
60 Escitalopram
(Synonym: Act Escitalopram ODT)		[3] Citalopram; Escitalopram; Escitalopram oxalate[3] D02567 ,
D07704 ,
D07913 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 2, 6, 13
61 Estradiol
(Synonym: Activelle)		[1] Estradiol[8] D00105 ,
D01413 ,
D01617 ,
D01953 ,
D04061 ,
D04063 ,
D04064 ,
D04065 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299
62 Ethanol
(Synonym: Victis Active Defense Essential)		[3] Alcohol; Ethanol; Prednisone[4] D00068 ,
D02798 ,
D04855 ,
D06542 		--[7] 13, 51, 58, 97, 279, 280, 298
63 Ezetimibe
(Synonym: Act Ezetimibe)		[2] Ezetimibe; Ezetrol[1] D01966 [1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260
64 Famciclovir
(Synonym: Act Famciclovir)		[1] Famciclovir[1] D00317 --[1] 13
65 Famotidine
(Synonym: Good Sense Dual Action Complete)		[2] FAMOTIDINA; Famotidine[1] D00318 [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[7] 6, 46, 61, 86, 98, 107, 300
66 Fentanyl
(Synonym: Actiq)		[1] Fentanyl[2] D00320 ,
D01399 (Name: ACTIQ)		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[4] 46, 70, 215, 231
67 Finasteride
(Synonym: Act Finasteride)		[1] Finasteride[1] D00321 [1] SRD5A2 💬[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[1] 6
68 Fluconazole
(Synonym: Act Fluconazole)		[2] Diflucan; FLUCONAZOLE[2] D00322 ,
D01429 		--[2] 96, 225
69 Fluoxetine
(Synonym: Act Fluoxetine)		[5] Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC[2] D00326 ,
D00823 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206
70 Fluticasone propionate
(Synonym: Flovent Inhalers-aem Inh-orl250mcg/actuation)		[3] Flovent; Fluticasone; Fluticasone propionate[1] D01708 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 98, 228
71 Folic acid
(Synonym: Acti-folic + Dibencozide Caplets)		[5] Acide folique; Folate; Folic acid; Multivitamin; NICOTINAMIDE[1] D00070 --[6] 6, 13, 41, 46, 49, 84
72 Fulvestrant
(Synonym: Act Fulvestrant)		[2] Faslodex; Fulvestrant[1] D01161 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 49, 86
73 Furosemide
(Synonym: Active-Medicated specimen collection kit)		[2] Furosemide; Furosemide Injection[1] D00331 [1] SLC12A2 💬[3] Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬[1] 6
74 Gabapentin
(Synonym: ACTIVE-PAC with Gabapentin)		[4] GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN[1] D00332 [5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298
75 Glycerin
(Synonym: Correct Essential Activator)		[3] Bee venom; Glycerine; Glycerol[1] D00028 --[6] 6, 13, 79, 265, 316, 317
76 Glycolic acid
(Synonym: bdr Re-action deep low base skin refiner exfoliation essence)		[1] Glycolic acid---[1] 65
77 Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen
(Synonym: Act-hib)		[2] Act-hib; ActHIB---[5] 14, 61, 62, 66, 222
78 Haloperidol
(Synonym: Haloperidol Long Acting)		[1] Haloperidol[2] D00136 ,
D01898 		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
79 Histamine
(Synonym: ActivOn Ultra Strength Arthritis)		[1] Histamine[1] D08040 [4] HRH1,
HRH2,
HRH3,
HRH4 💬		[4] Calcium signaling pathway, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 13
80 Hydrochlorothiazide
(Synonym: Act Losartan/hct)		[2] Esidrix; Hydrochlorothiazide[1] D00340 [1] SLC12A3 💬-[4] 13, 67, 225, 235
81 Hydrocortisone [6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] D00088 (Name: Acticort (TN))[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[11] 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
82 Hydrocortisone acetate
(Synonym: Actinac Pwr)		[2] Hydrocortisone; HYDROCORTISONE ACETATE[1] D00165 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
83 Ibuprofen
(Synonym: Rx Act Ibuprofen)		[2] Ibuprofen; IBUPROFEN 200MG[4] D00126 ,
D01122 ,
D04490 ,
D06606 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299
84 Imatinib
(Synonym: Imatinib Actavis)		[4] Gleevec; GLIVEC; IMATINIB; Imatinib Mesylate[2] D01441 ,
D08066 		[3] ABL1,
KIT,
PDGFRA 💬		[32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
85 Insulin human
(Synonym: Actrapid Innolet)		[1] Human insulin[2] D00085 ,
D03230 		[1] INSR 💬[22] AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[2] 96, 156
86 Insulin-like growth factor II
(Synonym: Multiplication-stimulating activity III-2)		[0] ---[1] 19
87 Interferon gamma-1b
(Synonym: Actimmune)		[2] ACTIMMUNE; Interferon gamma-1b[1] D00747 (Name: Actimmune (TN))[2] IFNGR1,
IFNGR2 💬		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326
88 Iodine
(Synonym: Multi-actin)		[2] Iodine; Iodo[1] D00108 --[3] 28, 46, 88
89 Irbesartan
(Synonym: Act Irbesartan/hct)		[2] Aprovel; Irbesartan[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[4] 66, 167, 168, 222
90 Iron
(Synonym: Active OB)		[1] Iron---[6] 18, 96, 97, 238, 254, 284
91 Levetiracetam
(Synonym: Levetiracetam Actavis)		[2] KEPPRA; Levetiracetam[1] D00709 [1] SV2A 💬[1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307
92 Levofloxacin
(Synonym: Act Levofloxacin)		[2] Levaquin; Levofloxacin[2] D00588 ,
D08120 		--[5] 46, 53, 84, 85, 299
93 Levonorgestrel
(Synonym: Take Action)		[1] LEVONORGESTREL[1] D00950 [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13
94 Lidocaine
(Synonym: HUSH Fast Acting Topical Anesthetic)		[4] Aloe; Lidocaine; Lignocaine; Xylocaine[3] D00358 ,
D02086 ,
D08127 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
95 Lisinopril
(Synonym: Act Lisinopril)		[2] Lisinopril; Zestril[2] D00362 ,
D08131 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 19, 46, 49, 66, 67, 113, 222
96 Loperamide
(Synonym: Rx Act Anti Diarrheal)		[2] Loperamide; Loperamide hydrochloride[3] D00729 ,
D07113 ,
D08144 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97
97 Losartan
(Synonym: Act Losartan)		[3] Cozaar; Losartan; LOSARTAN POTASSIUM[2] D00357 ,
D08146 		[1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
98 Lovastatin
(Synonym: Act Lovastatin)		[1] LOVASTATIN[1] D00359 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
99 Magnesium
(Synonym: Usana Optimizer Actical Plus Calcium-magnesium-vitamin D3-silicon Tablets)		[1] Magnesium---[21] 3, 6, 11, 13, 15, 46, 51, 64, 70, 93, 97, 111, 166, 225, 235, 256, 284, 291, 296, 297, 298
100 Magnesium hydroxide
(Synonym: Tums Dual Action)		[1] Magnesium hydroxide[1] D00731 --[1] 284
101 Magnesium oxide
(Synonym: Active FE)		[1] Magnesium oxide[1] D01167 --[3] 6, 166, 291
102 Maltodextrin
(Synonym: Re-action E)		[1] Maltodextrin[1] D02329 --[4] 6, 13, 96, 97
103 Meloxicam
(Synonym: Act Meloxicam)		[1] Meloxicam[1] D00969 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 46, 49, 271, 296
104 Memantine
(Synonym: Act Memantine)		[3] Ebixa; MEMANTINE; MEMANTINE HYDROCHLORIDE[2] D04905 ,
D08174 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[7] 2, 6, 8, 13, 49, 127, 205
105 Metformin
(Synonym: Actoplus Met)		[5] Metformin; Metformin HCl; Metformin Hydrochloride; Metformina; Metformine[2] D00944 ,
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
106 Methylphenidate
(Synonym: Act Methylphenidate ER)		[3] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin[2] D01296 ,
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206
107 Mineral oil
(Synonym: Phillips Dual Action)		[1] Paraffin Oil[1] D05042 --[1] 291
108 Misoprostol
(Synonym: Act Diclo-miso)		[1] Misoprostol[1] D00419 [3] PTGER2,
PTGER3,
PTGER4 💬		[9] Calcium signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway 💬[3] 46, 70, 271
109 Moxifloxacin
(Synonym: Act Moxifloxacin)		[2] Moxifloxacin; Moxifloxacin hydrochloride[2] D00874 ,
D08237 		--[9] 2, 6, 46, 49, 85, 86, 113, 240, 299
110 Nabilone
(Synonym: Act Nabilone)		[1] NABILONE[1] D05099 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[2] 6, 13
111 Naproxen
(Synonym: Rx Act All Day Pain Relief)		[5] Naprosyn; NAPROXEN; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid[1] D00118 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 13, 46, 107, 271
112 Neomycin
(Synonym: Dual Action Cream)		[1] Neomycin[1] D08260 --[3] 96, 97, 296
113 Niacin
(Synonym: Fusion Activator Formula Tab)		[2] Niacin; Nicotinic acid[1] D00049 --[4] 6, 78, 79, 265
114 Nicotinamide
(Synonym: MEDIKOii Bio Active Vital Shot Ampoule)		[4] Ginseng; Multivitamin; Niacinamide; Nicotinamide[1] D00036 --[11] 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
115 Nifedipine
(Synonym: Nu-nifedipine-PA - Prolonged Action Tab)		[1] Nifedipine[1] D00437 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 50, 81
116 Norethisterone
(Synonym: Activelle Ld)		[3] Norethindrone; Ortho-novum; Ortho-Novum 777[2] D00182 ,
D00953 		[1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[4] 13, 46, 49, 299
117 Olanzapine
(Synonym: Act Olanzapine ODT)		[2] Olanzapine; Zyprexa[2] D00454 ,
D06623 		[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
118 Ondansetron
(Synonym: Act Ondansetron)		[1] Ondansetron[2] D00456 ,
D00678 		[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[4] 6, 97, 107, 231
119 Oxycodone
(Synonym: Act Oxycodone CR)		[3] Oxycodone; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen[3] D03783 ,
D05312 ,
D05462 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298
120 Pantoprazole
(Synonym: Act Pantoprazole)		[1] Pantoprazole[2] D02593 ,
D05353 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 13, 65
121 Paroxetine
(Synonym: Act Paroxetine)		[1] Paroxetine[4] D02260 ,
D02362 ,
D05374 ,
D05375 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85
122 Petrolatum
(Synonym: Rx Act Hemorrhoidal)		[1] Petrolatum[1] D05331 --[3] 35, 158, 162
123 Phenylephrine
(Synonym: Mucinex Multi-action Cold & Sinus Liquid)		[1] Phenylephrine[2] D00511 ,
D08365 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22
124 Pioglitazone
(Synonym: Actos)		[1] Pioglitazone[2] D00945 (Name: Actos (TN)),
D08378 (Name: Actos (TN))		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
125 Potassium
(Synonym: Multi-actin)		[1] Potassium[1] D08403 --[12] 36, 46, 66, 67, 88, 94, 98, 115, 167, 179, 215, 235
126 Pramipexole
(Synonym: Act Pramipexole)		[7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; PRAMIPEXOLE; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20
127 Pravastatin
(Synonym: Act Pravastatin)		[2] Pravastatin; Pravastatin sodium[2] D00893 ,
D08410 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
128 Pregabalin
(Synonym: Act Pregabalin)		[2] Lyrica; Pregabalin[1] D02716 [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298
129 Progesterone
(Synonym: Act Progesterone Injection)		[1] Progesterone[1] D00066 [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 76
130 Pseudoephedrine
(Synonym: Actifed Tablets)		[1] Pseudoephedrine[4] D00485 ,
D05648 ,
D05649 ,
D08449 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17
131 Pyridoxine
(Synonym: Active OB)		[2] Pyridoxine; Vitamin B6[2] D02179 ,
D08454 		--[5] 6, 93, 145, 206, 320
132 Quetiapine
(Synonym: Act Quetiapine)		[2] Quetiapine; Seroquel[2] D00458 ,
D08456 		[2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13
133 Raloxifene
(Synonym: Act Raloxifene)		[2] Raloxifene; Raloxifene hydrochloride[2] D02217 ,
D08465 		[2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 46
134 Ramipril
(Synonym: Act Ramipril)		[1] Ramipril[1] D00421 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257
135 Ranitidine
(Synonym: Rx Act Heartburn Relief)		[1] Ranitidine[2] D00422 ,
D00673 		[1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 13, 65
136 Repaglinide
(Synonym: Act Repaglinide)		[1] Repaglinide[1] D00594 [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[3] 6, 21, 299
137 Riboflavin
(Synonym: Active OB)		[2] Riboflavin; Vitamin B2[3] D00050 ,
D01622 ,
D01913 		--[8] 13, 38, 46, 96, 97, 162, 168, 265
138 Risedronic acid
(Synonym: Actonel Plus Calcium)		[3] Risedronate; Risedronate sodium; Risedronic acid[3] D00942 (Name: Actonel (TN)),
D03234 (Name: Actonel (TN)),
D08484 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274
139 Risperidone
(Synonym: Act Risperidone)		[1] Risperidone[1] D00426 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206
140 Rivastigmine
(Synonym: Act Rivastigmine Patch 5)		[3] EXELON; RIVASTIGMINE; Rivastigmine Transdermal System[2] D02558 ,
D03822 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13
141 Rosuvastatin
(Synonym: Act Rosuvastatin)		[3] Crestor; Rosuvastatin; Rosuvastatin calcium[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
142 Salicylic acid
(Synonym: Avon Clearskin 2 Triple Action Astringent Cleansing Lotion)		[2] 2-Hydroxybenzoic acid; Salicylic acid[1] D00097 --[1] 97
143 Selenium
(Synonym: Multi-actin)		[1] Selenium---[4] 13, 96, 278, 298
144 Sertraline
(Synonym: Act Sertraline)		[1] Sertraline[2] D00825 ,
D02360 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 206
145 Sildenafil
(Synonym: Sildenafil Actavis)		[6] Mysildecard; Revatio; Sildenafil; SILDENAFIL CITRATE; SILDENAFILO; Viagra[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
146 Silicon
(Synonym: Usana Optimizer Actical Plus Calcium-magnesium-vitamin D3-silicon Tablets)		[1] Silicon---[1] 6
147 Silver
(Synonym: Argentyn 23Bio active silver Bio active silver hydrosol)		[1] Silver---[2] 35, 162
148 Simvastatin
(Synonym: Act Simvastatin)		[3] Simvastatin; Simvastatina; Simvastatine[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
149 Sodium fluoride
(Synonym: ACT Anticavity Fluoride Iced Berry)		[2] Beam; Sodium fluoride[1] D00943 --[1] 51
150 Solifenacin
(Synonym: Act Solifenacin)		[2] Solifenacin; Solifenacin Succinate[2] D01269 ,
D08522 		[1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53
151 Spectinomycin
(Synonym: Actinospectacina)		[0] [2] D00869 ,
D08526 		--[1] 13
152 Tadalafil
(Synonym: Act Tadalafil)		[4] Adcirca; Cialis; Tadalafil; TADALAFILO[1] D02008 [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210
153 Telmisartan
(Synonym: Act Telmisartan/hct)		[1] Telmisartan[1] D00627 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 66, 67
154 Temozolomide
(Synonym: Act Temozolomide)		[1] Temozolomide[1] D06067 --[1] 34
155 Terbinafine
(Synonym: Act Terbinafine)		[1] Terbinafine[2] D02219 ,
D02375 		--[3] 96, 97, 271
156 Tetracycline
(Synonym: Actisite)		[2] Tetracyclin; Tetracycline[1] D00201 --[5] 13, 36, 46, 53, 97
157 Thiamine
(Synonym: Active FE)		[2] Thiamine; Vitamin B1[1] D08580 --[5] 8, 13, 93, 145, 265
158 Timolol
(Synonym: Act Dorzotimolol)		[2] Timolol; TIMOLOL MALEATE[3] D00378 ,
D00603 ,
D08600 		[2] ADRB1,
ADRB2 💬		[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 157, 227
159 Tocilizumab
(Synonym: Actemra ACTPen)		[3] ACTEMRA; ROACTEMRA; TOCILIZUMAB[1] D02596 (Name: Actemra (TN))[1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
160 Topotecan
(Synonym: Topotecan Actavis)		[1] Topotecan[2] D02168 ,
D08618 		[1] TOP1 💬-[1] 25
161 Tramadol
(Synonym: Act Tramadol/acet)		[2] Tramadol; Ultracet[2] D01355 ,
D08623 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271
162 Ubidecarenone
(Synonym: Acti-ubiquinone 50 Cap 50mg)		[3] Coenzyme Q-10; Coenzyme Q10; CoQ10[1] D01065 --[13] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 193, 214, 215
163 Ursodeoxycholic acid
(Synonym: Actigall)		[4] UDCA; URSODEOXYCHOLIC ACID; Ursodiol; Ursofalk[1] D00734 (Name: Actigall (TN))[1] NR1H4 💬[1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299
164 Valsartan
(Synonym: Act Valsartan)		[3] Diovan; Entresto; Valsartan[1] D00400 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 57, 58, 66, 75, 218, 222, 224
165 Venlafaxine
(Synonym: Act Venlafaxine XR)		[2] Venlafaxine; Venlafaxine Hydrochloride[2] D00821 ,
D08670 		[2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 46
166 Vitamin A
(Synonym: Acti-retinol & Zn Caplet)		[1] Vitamin A[2] D00069 ,
D06543 		[2] RARA,
RARB 💬		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[3] 13, 53, 90
167 Vitamin E
(Synonym: Acti-D Alphacopherol Cap 400unit)		[2] Alpha-tocopherol; Vitamin E[1] D02331 --[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317
168 Water
(Synonym: Activase RT-PA)		[9] AVONEX; ENBREL; Glucagon; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION[1] D00001 --[23] 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299
169 Zinc
(Synonym: Acti-retinol & Zn Caplet)		[3] Nicotinamide; Wilzin; Zinc---[4] 2, 113, 171, 299
170 Zinc acetate
(Synonym: Action Cream)		[2] Wilzin; Zinc acetate[1] D06408 --[2] 171, 299
171 Zoledronic acid
(Synonym: Act Zoledronic Acid)		[4] ACLASTA; Zoledronate; Zoledronic acid; Zometa[4] D01968 ,
D06378 ,
D06379 ,
D08689 		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
172 Zopiclone
(Synonym: Act Zopiclone)		[1] Zopiclone[1] D01372 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6