Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Synonym: Nalocet)
[5] Acetaminophen; Oxycodone/Acetaminophen; PARACETAMOL; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Buprenorphine
(Synonym: Teva-buprenorphine/naloxone)
[1] Buprenorphine[2] D00836 ,
D07132
[2] OPRK1,
OPRM1 💬
[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[3] 46, 70, 298
3 Bupropion
(Synonym: Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release)
[2] Bupropion; Bupropion Hydrochloride[3] D00817 ,
D07591 ,
D07938
[2] SLC6A2,
SLC6A3 💬
[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
4 Cromoglicic acid
(Synonym: Nalcrom)
[4] Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium[2] D00526 ,
D07753
--[3] 2, 85, 98
5 Nalbuphine [2] Nalbuphine; NALBUPHINE HYDROCHLORIDE[2] D00843 (Name: Nalbuphine hydrochloride),
D08246 (Name: Nalbuphine)
[3] OPRD1,
OPRK1,
OPRM1 💬
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85
6 Nalmefene [1] Nalmefene[1] D05111 (Name: Nalmefene)[3] OPRD1,
OPRK1,
OPRM1 💬
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6
7 Naloxone [2] Naloxone; NALOXONE HYDROCHLORIDE[2] D01340 (Name: Naloxone hydrochloride),
D08249 (Name: Naloxone)
[3] OPRD1,
OPRK1,
OPRM1 💬
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226
8 Naltrexone [2] Naltrexone; Naltrexone hydrochloride[2] D02095 (Name: Naltrexone hydrochloride),
D05113 (Name: Naltrexone)
[3] OPRD1,
OPRK1,
OPRM1 💬
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[13] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
9 Oxycodone
(Synonym: Nalocet)
[3] OXYCODONE; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen[3] D03783 ,
D05312 ,
D05462
[3] OPRD1,
OPRK1,
OPRM1 💬
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298
10 Triamcinolone
(Synonym: Naltrexone)
[4] Kenalog; Naltrexone; Triamcinolone; TRIAMCINOLONE ACETONIDE[5] D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216
[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298