Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Oxygen [1] Oxygen[3] Medical air; Nitrogen; Oxygen; --[20] 6, 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 168, 193, 226, 271, 294, 299, 330
2 Oxiglutatione [1] Glutathione[2] GLUTATHIONE; Reduced glutathione; --[2] 6, 299
3 Orotic acid -[0] ---
4 Oxytocin [1] Oxytocin[2] Oxytocin; Syntocinon; [1] OXTR 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[6] 6, 72, 127, 193, 206, 226
5 Oxytetracycline -[0] ---
6 Octreotide [1] Octreotide[3] Octreotide; OCTREOTIDE ACETATE; Sandostatin LAR; [1] SSTR2 💬[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[7] 67, 75, 84, 85, 89, 193, 227
7 Ofloxacin -[0] ---
8 Olanzapine [1] Olanzapine[2] OLANZAPINE; Zyprexa; [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
9 Omeprazole [1] Omeprazole[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
10 Ondansetron [1] Ondansetron[1] Ondansetron; [5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[4] 6, 97, 107, 231
11 Oxamniquine -[0] ---
12 Oxandrolone [1] Oxandrolone[1] Oxandrolone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 211, 285
13 Oxaprozin -[0] ---
14 Oxazepam -[0] ---
15 Oxybutynin [1] Oxybutynin[1] Oxybutynin; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53
16 Oxymetholone -[0] ---
17 Oxcarbazepine [1] Oxcarbazepine[2] Oxcarbazepine; Trileptal; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 13
18 Ondansetron hydrochloride hydrate [1] Ondansetron[1] Ondansetron; [5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[4] 6, 97, 107, 231
19 Oxybutynin chloride [1] Oxybutynin[1] Oxybutynin; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53
20 Olsalazine sodium [1] Olsalazine[1] Olsalazine; --[1] 271
21 Orphenadrine citrate -[0] ---
22 Oxiconazole nitrate [1] Oxiconazole[1] Oxiconazole; --[1] 160
23 Oseltamivir phosphate [1] Oseltamivir[1] Oseltamivir; --[2] 97, 299
24 Oxacillin sodium -[0] ---
25 Oxyphencyclimine hydrochloride -[0] ---
26 Oxymetazoline hydrochloride -[0] ---
27 Oxabolone cipionate -[0] ---
28 Oxethazaine -[0] ---
29 Olopatadine hydrochloride -[0] ---
30 Olmesartan medoxomil -[0] ---
31 Omeprazole sodium [1] Omeprazole[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
32 Oxypertine -[0] ---
33 Oxazolam -[0] ---
34 Oxymetebanol -[0] ---
35 Osalmid -[0] ---
36 Oxytetracycline hydrochloride -[0] ---
37 Ozagrel hydrochloride hydrate -[0] ---
38 Oxatomide [1] Oxatomide[1] Oxatomide; [1] ALOX5 💬[6] Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬[1] 113
39 Oxaliplatin -[0] ---
40 Omapatrilat -[0] ---
41 Oxtriphylline [1] Theophylline[1] Theophylline; [18] ADORA1,
ADORA2A,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		[24] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299
42 Oxolinic acid -[0] ---
43 Oleic acid [1] Oleic Acid[1] Oleic Acid; --[2] 13, 299
44 Oxypurinol -[0] ---
45 Orphenadrine hydrochloride -[0] ---
46 Ocinaplon -[0] ---
47 Ocaperidone -[0] ---
48 Olive oil [1] Olive oil[1] Olive Oil; --[3] 13, 49, 53
49 Opium -[0] ---
50 Oxycodone terephthalate [1] Oxycodone[3] OXYCODONE; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298
51 Orlistat -[0] ---
52 Ocrelizumab [1] Ocrelizumab[2] OCRELIZUMAB; OCREVUS; [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[3] 13, 46, 49
53 Ocrylate -[0] ---
54 Octanoic acid -[0] ---
55 Octinoxate -[0] ---
56 Octisalate -[0] ---
57 Octocrylene -[0] ---
58 Octyldodecanol -[0] ---
59 Olaflur -[0] ---
60 Olmesartan -[0] ---
61 Omalizumab [1] Omalizumab[2] Omalizumab; XOLAIR; [1] FCER1A 💬[4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299
62 Omega-3-acid ethyl esters -[0] ---
63 Omeprazole magnesium [1] Omeprazole[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
64 Omeprazole sodium injection [1] Omeprazole[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
65 Onercept -[0] ---
66 Opebacan -[0] ---
67 Oprelvekin [1] Oprelvekin[5] IL-11; Interleukin 11; Interleukin-11; Oprelvekin; Recombinant interleukin-11; [1] IL11RA 💬[3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[2] 96, 288
68 Oregovomab -[0] ---
69 Ornidazole -[0] ---
70 Oxfendazole -[0] ---
71 Oxfenicine -[0] ---
72 Oxibendazole -[0] ---
73 Oxidronic acid -[0] ---
74 Oxybenzone -[0] ---
75 Oxycodone [1] Oxycodone[3] Oxycodone; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298
76 Oxyphenbutazone hydrate -[0] ---
77 Oxyphenisatin acetate -[0] ---
78 Oxyquinoline [1] Oxyquinoline[1] Oxine; --[1] 13
79 Oxytetracycline calcium -[0] ---
80 Oxycodone hydrochloride hydrate [1] Oxycodone[3] OXYCODONE; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen; [3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298
81 Octreotide acetate [1] Octreotide[3] Octreotide; OCTREOTIDE ACETATE; Sandostatin LAR; [1] SSTR2 💬[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[7] 67, 75, 84, 85, 89, 193, 227
82 Olanzapine pamoate [1] Olanzapine[2] Olanzapine; Zyprexa; [11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
83 Oxyphenonium bromide -[0] ---
84 Oxaceprol -[0] ---
85 Ornipressin -[0] ---
86 Oxametacin -[0] ---
87 Oxycinchophen -[0] ---
88 Oxitriptan -[0] ---
89 Oxaflozane -[0] ---
90 Oxiracetam -[0] ---
91 Oxolamine -[0] ---
92 Oxomemazine -[0] ---
93 O-Acetyldihydrocodeine hydrochloride -[0] ---
94 Octenidine -[0] ---
95 Oblimersen -[0] ---
96 Olopatadine -[0] ---
97 Olsalazine [1] Olsalazine[1] Olsalazine; --[1] 271
98 Omoconazole -[0] ---
99 Opipramol -[0] ---
100 Orbifloxacin -[0] ---
101 Orciprenaline -[0] ---
102 Ormeloxifene -[0] ---
103 Ornithine [1] Ornithine[1] Ornithine; --[2] 245, 251
104 Orphenadrine -[0] ---
105 Oseltamivir [1] Oseltamivir[1] Oseltamivir; --[2] 97, 299
106 Oxacillin -[0] ---
107 Oxeladin -[0] ---
108 Oxetorone -[0] ---
109 Oxiconazole [1] Oxiconazole[1] Oxiconazole; --[1] 160
110 Oxilofrine -[0] ---
111 Oxprenolol -[0] ---
112 Oxybuprocaine [1] Oxybuprocaine[1] Oxybuprocaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6
113 Oxyfedrine -[0] ---
114 Oxymetazoline -[0] ---
115 Oxymorphone [1] Oxymorphone[1] Opana; [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 70
116 Oxyphenbutazone -[0] ---
117 Oxyphencyclimine -[0] ---
118 Oxyphenisatine -[0] ---
119 Ozagrel -[0] ---
120 Odanacatib -[0] ---
121 Omacetaxine mepesuccinate -[0] ---
122 Ospemifene -[0] ---
123 Otelixizumab [1] Otelixizumab[1] Otelixizumab; [3] CD3D,
CD3E,
CD3G 💬		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 46
124 Ofatumumab [1] Ofatumumab[4] Arzerra; HuMax-CD20; Kesimpta; OFATUMUMAB; [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[3] 13, 35, 46
125 Obinutuzumab [1] Obinutuzumab[2] Gazyvaro; OBINUTUZUMAB; [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[2] 49, 222
126 Obeticholic acid [1] Obeticholic acid[4] 6-ECDCA; 6-ethylchenodeoxycholic acid; Obeticholic Acid; Ocaliva; [1] NR1H4 💬[1] Bile secretion 💬[3] 93, 265, 296
127 Otenabant -[0] ---
128 Ozenoxacin -[0] ---
129 Onapristone -[0] ---
130 Ocriplasmin -[0] ---
131 Omadacycline [1] Omadacycline[1] Omadacycline; --[1] 299
132 Omecamtiv mecarbil -[0] ---
133 Orvepitant -[0] ---
134 Olaparib [1] Olaparib[1] Olaparib; [2] PARP1,
PARP2 💬		[5] Apoptosis, Base excision repair, Diabetic cardiomyopathy, NF-kappa B signaling pathway, Necroptosis 💬[2] 86, 285
135 Olaratumab -[0] ---
136 Onartuzumab -[0] ---
137 Oxelumab -[0] ---
138 Ozoralizumab [1] Ozoralizumab[1] Ozoralizumab; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46
139 Ondelopran -[0] ---
140 Olodaterol -[0] ---
141 Orteronel -[0] ---
142 Omarigliptin -[0] ---
143 Oprozomib -[0] ---
144 Ozanezumab [1] Ozanezumab[1] Ozanezumab; [1] RTN4 💬[1] Alzheimer disease 💬[1] 2
145 Ombitasvir -[0] ---
146 Omipalisib -[0] ---
147 Onalespib -[0] ---
148 Obiltoxaximab -[0] ---
149 Olipudase alfa [1] Olipudase alfa[1] Olipudase alfa; [1] SMPD1 💬[5] Lysosome, Metabolic pathways, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19
150 Opicapone [1] Opicapone[2] Ongentys; OPICAPONE; [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6
151 Olmutinib -[0] ---
152 Ofranergene obadenovec -[0] ---
153 Oleclumab -[0] ---
154 Omaveloxolone [1] Omaveloxolone[1] Omaveloxolone; [1] NFE2L2 💬[7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18
155 Omidenepag isopropyl -[0] ---
156 Ozanimod [1] Ozanimod[2] Ozanimod; Zeposia; [5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬		[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 96, 97
157 Osilodrostat [1] Osilodrostat[1] OSILODROSTAT; [1] CYP11B2 💬[3] Aldosterone synthesis and secretion, Metabolic pathways, Steroid hormone biosynthesis 💬[1] 75
158 Olumacostat glasaretil -[0] ---
159 Oliceridine -[0] ---
160 Olendalizumab -[0] ---
161 Otilimab [1] Otilimab[1] Otilimab; [1] CSF2 💬[16] Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬[2] 46, 256
162 Olacaftor -[0] ---
163 Oxycodegol -[0] ---
164 Olorinab -[0] ---
165 Onvansertib -[0] ---
166 Olinciguat -[0] ---
167 Obexelimab -[0] ---
168 Omburtamab -[0] ---
169 Odronextamab -[0] ---
170 Onasemnogene abeparvovec [1] Onasemnogene abeparvovec[3] ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-xioi; Zolgensma; [1] SMN1 💬-[1] 3
171 Odevixibat [1] Odevixibat[1] Odevixibat; [1] SLC10A2 💬[1] Bile secretion 💬[3] 296, 297, 338
172 Opicinumab [1] Opicinumab[1] Opicinumab; [1] LINGO1 💬-[1] 13
173 Oteseconazole -[0] ---
174 Oportuzumab monatox -[0] ---
175 Odesivimab -[0] ---
176 Orilanolimab [1] Orilanolimab[1] ORILANOLIMAB; [1] FCGRT 💬-[1] 61
177 Orelabrutinib [1] Orelabrutinib[1] Orelabrutinib; [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 13, 61, 63