Drug Description in Trials / DrugBank / KEGG DRUG


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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Riboflavin [1] Riboflavin[2] Riboflavin; Vitamin B2; --[8] 13, 38, 46, 96, 97, 162, 168, 265
2 Resorcinol -[0] ---
3 Reserpine -[0] ---
4 Rescinnamine -[0] ---
5 Rifampin [1] Rifampicin[2] Rifampicin; Rifampin; --[9] 6, 13, 17, 46, 84, 86, 93, 299, 338
6 Ramipril [1] Ramipril[1] Ramipril; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257
7 Ranitidine [1] Ranitidine[1] Ranitidine; [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 13, 65
8 Ribavirin [1] Ribavirin[2] Copegus; Ribavirin; --[2] 2, 96
9 Rifabutin [1] Rifabutin[1] RIFABUTIN; --[1] 96
10 Risperidone [1] Risperidone[1] Risperidone; [2] DRD2,
HTR2A 💬
[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206
11 Ritonavir [1] Ritonavir[2] Norvir; Ritonavir; --[3] 2, 86, 265
12 Rofecoxib [1] Rofecoxib[1] Rofecoxib; [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
13 Repaglinide [1] Repaglinide[1] Repaglinide; [2] ABCC8,
KCNJ11 💬
[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[3] 6, 21, 299
14 Rosiglitazone maleate [1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265
15 Ranitidine hydrochloride [1] Ranitidine[1] Ranitidine; [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 13, 65
16 Rizatriptan benzoate -[0] ---
17 Rabeprazole sodium [1] Rabeprazole[1] Rabeprazole; [2] ATP4A,
ATP4B 💬
[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 2, 51
18 Rocuronium bromide [1] Rocuronium[1] Rocuronium; [16] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB2,
CHRNB3,
CHRNB4 💬
[15] Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Nicotine addiction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 296
19 Riluzole [1] Riluzole[2] Rilutek; Riluzole; [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬
[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
20 Ropinirole hydrochloride [1] Ropinirole[3] Requip; Ropinirole; ROPINIROLE HYDROCHLORIDE; [3] DRD2,
DRD3,
DRD4 💬
[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 74, 309
21 Rifapentine -[0] ---
22 Rimantadine hydrochloride -[0] ---
23 Risedronate sodium [1] Risedronic acid[3] Risedronate; RISEDRONATE SODIUM; Risedronic acid; [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274
24 Raltitrexed -[0] ---
25 Rebamipide [1] Rebamipide[1] Rebamipide; --[4] 46, 53, 97, 271
26 Ramatroban [1] Ramatroban[1] Ramatroban; [2] PTGDR,
TBXA2R 💬
[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬[1] 13
27 Remifentanil hydrochloride [1] Remifentanil[2] Remifentanil; Remifentanyl; [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[2] 6, 70
28 Ritodrine hydrochloride -[0] ---
29 Riboflavin sodium phosphate [1] Riboflavin[2] Riboflavin; Vitamin B2; --[8] 13, 38, 46, 96, 97, 162, 168, 265
30 Roxithromycin [1] Roxithromycin[1] Roxithromycin; --[2] 46, 299
31 Ranimustine -[0] ---
32 Rolipram [1] Rolipram[1] Rolipram; [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬
[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 8, 13
33 Rokitamycin -[0] ---
34 Riboflavin butyrate [1] Riboflavin[2] RIBOFLAVIN; Vitamin B2; --[8] 13, 38, 46, 96, 97, 162, 168, 265
35 Rosuvastatin calcium [1] Rosuvastatin[3] Crestor; Rosuvastatin; Rosuvastatin calcium; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
36 Reglitazar -[0] ---
37 Raloxifene hydrochloride [1] Raloxifene[2] Raloxifene; Raloxifene hydrochloride; [2] ESR1,
ESR2 💬
[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 46
38 Rolitetracycline -[0] ---
39 Rosoxacin -[0] ---
40 Ritodrine -[0] ---
41 Resorcinol monoacetate -[0] ---
42 Rufloxacin -[0] ---
43 Rifamycin -[0] ---
44 Rifalazil -[0] ---
45 Rifaximin [1] Rifaximin[3] Rifaximin; RIFAXIMINA; Xifaxan; --[8] 6, 65, 93, 94, 96, 97, 99, 296
46 Ravuconazole -[0] ---
47 Rivastigmine tartrate [1] Rivastigmine[3] Exelon; Rivastigmine; Rivastigmine Transdermal System; [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13
48 Rasagiline mesylate [1] Rasagiline[4] Azilect; Rasagilina; Rasagiline; RASAGILINE MESYLATE; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 2, 5, 6, 13, 17, 58, 66
49 Reboxetine mesylate -[0] ---
50 Remoxipride -[0] ---
51 Remoxipride hydrochloride -[0] ---
52 Ramelteon [1] Ramelteon[2] Ramelteon; ROZEREM; [2] MTNR1A,
MTNR1B 💬
[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46
53 Rimabotulinumtoxin B [1] Botulinum toxin type B[3] Botulinum toxin type B; NEUROBLOC; RimabotulinumtoxinB; [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[4] 2, 6, 13, 51
54 Rituximab [1] Rituximab[6] MabThera; Rituxan; RITUXIMAB; Rixathon; Ruxience; TRUXIMA; [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[49] 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
55 Rebimastat -[0] ---
56 Rivastigmine [1] Rivastigmine[3] EXELON; Rivastigmine; Rivastigmine Transdermal System; [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13
57 Rubitecan -[0] ---
58 Ropivacaine hydrochloride [1] Ropivacaine[1] Ropivacaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 36, 46, 70
59 Racemethionine [1] Methionine[3] Butanoic acid; L-methionine; Methionine; --[7] 34, 75, 84, 93, 229, 298, 300
60 Racepinephrine -[0] ---
61 Raluridine -[0] ---
62 Ramoplanin -[0] ---
63 Ranibizumab [1] Ranibizumab[3] Lucentis; Ranibizumab; RhuFab V2; [1] VEGFA 💬[24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[4] 34, 166, 227, 301
64 Ranolazine [1] Ranolazine[3] RANEXA; Ranolazina; Ranolazine; --[6] 2, 58, 86, 96, 113, 114
65 Ranolazine hydrochloride [1] Ranolazine[3] RANEXA; Ranolazina; Ranolazine; --[6] 2, 58, 86, 96, 113, 114
66 Ranpirnase -[0] ---
67 Rasburicase -[0] ---
68 Raxibacumab -[0] ---
69 Regadenoson [1] Regadenoson[1] Regadenoson; [1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 58
70 Regramostim [1] Regramostim[2] GM-CSF; RhGM-CSF; [1] CSF2RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[1] 229
71 Repifermin -[0] ---
72 Retapamulin -[0] ---
73 Reteplase -[0] ---
74 Riboprine -[0] ---
75 Ridogrel -[0] ---
76 Rilapladib -[0] ---
77 Rimexolone -[0] ---
78 Rimonabant [1] Rimonabant[2] Acomplia; Rimonabant; [1] CNR1 💬[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 193
79 Ritanserin -[0] ---
80 Rivoglitazone -[0] ---
81 Rizatriptan sulfate -[0] ---
82 Roflumilast [1] Roflumilast[1] Roflumilast; [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬
[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 84, 299
83 Ronnel -[0] ---
84 Roquinimex -[0] ---
85 Rostaporfin -[0] ---
86 Rotigaptide -[0] ---
87 Rotigotine [1] Rotigotine[3] NEUPRO; ROTIGOTINA; Rotigotine; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 127
88 Roxarsone -[0] ---
89 Rufinamide [1] Rufinamide[2] Inovelon; RUFINAMIDE; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 144
90 Rupintrivir -[0] ---
91 Ruplizumab -[0] ---
92 Renzapride -[0] ---
93 Ranirestat -[0] ---
94 Relacatib -[0] ---
95 Rilonacept [1] Rilonacept[1] Rilonacept; [2] IL1A,
IL1B 💬
[45] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬[4] 51, 106, 107, 266
96 Romidepsin -[0] ---
97 Rusalatide acetate -[0] ---
98 Raltegravir [1] Raltegravir[2] ISENTRESS; Raltegravir; --[4] 13, 26, 93, 265
99 Rhubarb -[0] ---
100 Rosin -[0] ---
101 Rociverine -[0] ---
102 Rivaroxaban [1] Rivaroxaban[2] RIVAROXABAN; Xarelto; [1] F10 💬[1] Complement and coagulation cascades 💬[5] 46, 49, 75, 91, 210
103 Ronifibrate -[0] ---
104 Ritiometan -[0] ---
105 Rupatadine [1] Rupatadine[1] Rupatadine; [2] HRH1,
PTAFR 💬
[4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬[1] 46
106 Rabeprazole [1] Rabeprazole[1] Rabeprazole; [2] ATP4A,
ATP4B 💬
[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 2, 51
107 Racecadotril -[0] ---
108 Raloxifene [1] Raloxifene[2] Raloxifene; Raloxifene hydrochloride; [2] ESR1,
ESR2 💬
[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 46
109 Ramosetron -[0] ---
110 Rasagiline [1] Rasagiline[4] AZILECT; Rasagilina; RASAGILINE; RASAGILINE MESYLATE; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 2, 5, 6, 13, 17, 58, 66
111 Raubasine -[0] ---
112 Reboxetine -[0] ---
113 Remifentanil [1] Remifentanil[2] Remifentanil; Remifentanyl; [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[2] 6, 70
114 Reproterol -[0] ---
115 Ribostamycin -[0] ---
116 Rilmenidine [1] Rilmenidine[2] HYPERIUM; Rilmenidine; [3] ADRA2A,
ADRA2B,
ADRA2C 💬
[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 8
117 Rimantadine -[0] ---
118 Risedronic acid [1] Risedronic acid[3] Risedronate; Risedronate Sodium; Risedronic acid; [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274
119 Rizatriptan -[0] ---
120 Robenidine -[0] ---
121 Romifidine -[0] ---
122 Ropinirole [1] Ropinirole[3] REQUIP; Ropinirole; Ropinirole Hydrochloride; [3] DRD2,
DRD3,
DRD4 💬
[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 74, 309
123 Ropivacaine [1] Ropivacaine[1] Ropivacaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 36, 46, 70
124 Rosiglitazone [1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265
125 Rosuvastatin [1] Rosuvastatin[3] Crestor; Rosuvastatin; Rosuvastatin calcium; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
126 Roxatidine acetate -[0] ---
127 Ruscogenin -[0] ---
128 Rutoside -[0] ---
129 Ridaforolimus -[0] ---
130 Reparixin [1] Reparixin[1] Reparixin; [2] CXCR1,
CXCR2 💬
[7] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Human cytomegalovirus infection, Phospholipase D signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬[2] 298, 299
131 Reslizumab [1] Reslizumab[1] Reslizumab; [1] IL5 💬[13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[2] 44, 98
132 Retosiban -[0] ---
133 Rolofylline -[0] ---
134 Romiplostim [1] Romiplostim[2] NPLATE; Romiplostim; [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[4] 60, 63, 64, 65
135 Ropidoxuridine -[0] ---
136 Remikiren -[0] ---
137 Raspberry [1] Raspberry[1] Raspberry; --[1] 97
138 Radezolid -[0] ---
139 Ramucirumab -[0] ---
140 Retaspimycin -[0] ---
141 Riociguat [1] Riociguat[2] Adempas; RIOCIGUAT; [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 51, 84, 86, 88, 225, 299
142 Razupenem -[0] ---
143 Rilotumumab -[0] ---
144 Rindopepimut -[0] ---
145 Rintatolimod -[0] ---
146 Rontalizumab [1] Rontalizumab[1] Rontalizumab; [13] IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬
[25] Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 49
147 Rozrolimupab -[0] ---
148 Remestemcel-L [1] Remestemcel-L[3] Adult human mesenchymal stem cells; Prochymal; Remestemcel-L; --[3] 85, 96, 97
149 Rilpivirine -[0] ---
150 Riferminogene pecaplasmid -[0] ---
151 Royal jelly [1] Royal jelly[1] Royal jelly; --[1] 49
152 Rezatomidine -[0] ---
153 Ruxolitinib [1] Ruxolitinib[1] Ruxolitinib; [2] JAK1,
JAK2 💬
[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 228
154 Remogliflozin etabonate -[0] ---
155 Robatumumab -[0] ---
156 Rucaparib -[0] ---
157 Regorafenib -[0] ---
158 Radavirsen -[0] ---
159 Rigosertib [1] Rigosertib[1] Rigosertib; [1] PLK1 💬[4] Cell cycle, FoxO signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 36
160 Romosozumab [1] Romosozumab[2] Evenity; ROMOSOZUMAB; [1] SOST 💬[2] Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬[1] 274
161 Rebastinib -[0] ---
162 Ramatercept -[0] ---
163 Rabusertib -[0] ---
164 Radium Ra 223 dichloride -[0] ---
165 Rivipansel -[0] ---
166 Roxadustat -[0] ---
167 Ralimetinib -[0] ---
168 Relamorelin -[0] ---
169 Ricolinostat -[0] ---
170 Rimegepant -[0] ---
171 Rabacfosadine -[0] ---
172 Ralinepag [1] Ralinepag[1] RALINEPAG; [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[1] 86
173 Relebactam -[0] ---
174 Rolapitant -[0] ---
175 Rurioctocog alfa pegol [1] Rurioctocog alfa pegol[1] Rurioctocog alfa pegol; --[1] 288
176 Rasagiline tartrate [1] Rasagiline[4] AZILECT; Rasagilina; Rasagiline; Rasagiline mesylate; [1] MAOB 💬[14] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 2, 5, 6, 13, 17, 58, 66
177 Rociletinib -[0] ---
178 Ribociclib -[0] ---
179 Relugolix -[0] ---
180 Recanaclotide -[0] ---
181 Remetinostat -[0] ---
182 Revefenacin -[0] ---
183 Rovalpituzumab tesirine -[0] ---
184 Ropeginterferon alfa-2b -[0] ---
185 Risankizumab [1] Risankizumab[1] Risankizumab; [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[4] 37, 96, 97, 271
186 Ravulizumab [1] Ravulizumab[2] RAVULIZUMAB; ULTOMIRIS; [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 2, 11, 13, 50, 62, 66, 109
187 Rimiducid [1] Rimiducid[1] Rimiducid; [1] CASP9 💬[35] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[6] 19, 60, 65, 284, 285, 326
188 Ribaxamase -[0] ---
189 Rezafungin -[0] ---
190 Ruzasvir -[0] ---
191 Relenopride -[0] ---
192 Roluperidone -[0] ---
193 Reltecimod -[0] ---
194 Ravoxertinib -[0] ---
195 Rivoceranib -[0] ---
196 Reproxalap [1] Reproxalap[1] Reproxalap; --[1] 160
197 Rovazolac -[0] ---
198 Relacorilant [1] Relacorilant[2] CORT125134; Relacorilant; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 75
199 Relatlimab -[0] ---
200 Ripretinib -[0] ---
201 Reldesemtiv [1] Reldesemtiv[2] CK-2127107; RELDESEMTIV; [1] TNNC2 💬[1] Calcium signaling pathway 💬[2] 2, 3
202 Risdiplam [1] Risdiplam[2] EVRYSDI; Risdiplam; [1] SMN2 💬[1] Nucleocytoplasmic transport 💬[1] 3
203 Risuteganib -[0] ---
204 Remdesivir -[0] ---
205 Razuprotafib -[0] ---
206 Ravagalimab [1] Ravagalimab[1] Ravagalimab; [1] CD40 💬[17] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬[2] 53, 97
207 Romilkimab -[0] ---
208 Racemetyrosine -[0] ---
209 Rovafovir etalafenamide -[0] ---
210 Remimazolam -[0] ---
211 Retifanlimab -[0] ---
212 Rimtuzalcap -[0] ---
213 Ridinilazole -[0] ---
214 Rozanolixizumab [1] Rozanolixizumab[1] ROZANOLIXIZUMAB; [1] FCGRT 💬-[3] 11, 14, 63
215 Regdanvimab -[0] ---