Drug Description in Trials / DrugBank / KEGG DRUG


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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Tryptophan [1] Tryptophan[2] Propanoic acid; Tryptophan; --[2] 6, 75
2 Tyrosine [1] Tyrosine[4] Alanine; L-tyrosine; Propanoic acid; Tyrosine; --[5] 6, 75, 86, 111, 298
3 Threonine [1] Threonine[1] Threonine; --[3] 86, 96, 97
4 Taurine [1] Taurine[1] Taurine; --[2] 13, 337
5 Thioctic acid amide [1] Lipoic acid[3] Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid; --[5] 2, 5, 13, 14, 20
6 Trypsin, crystallized -[0] ---
7 Tobramycin [1] Tobramycin[9] Bethkis; TOBI; TOBI PODHALER; TOBRAMICINA; TOBRAMYCIN; Tobramycin inhalation solution; TOBRAMYCIN SULFATE; Tobramycine; Tobramycinum; --[1] 299
8 Testosterone [1] Testosterone[1] Testosterone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
9 Thioctic acid [1] Lipoic acid[3] Alpha Lipoic Acid; ALPHA-LIPOIC ACID; Lipoic acid; --[5] 2, 5, 13, 14, 20
10 Thrombin [1] Thrombin[1] Thrombin; --[2] 86, 88
11 Tretinoin [1] Tretinoin[5] ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID; [3] PML,
RARA,
RARB 💬
[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[6] 2, 62, 63, 75, 94, 231
12 Tacrolimus [1] Tacrolimus[2] Prograf; Tacrolimus; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
13 Trimethoprim [1] Trimethoprim[2] Bactrim; Trimethoprim; --[8] 36, 44, 49, 60, 61, 85, 298, 299
14 Testolactone -[0] ---
15 Tolmetin sodium -[0] ---
16 Tetracycline [1] Tetracycline[2] Tetracyclin; Tetracycline; --[5] 13, 36, 46, 53, 97
17 Trolamine -[0] ---
18 Temazepam -[0] ---
19 Theophylline [1] Theophylline[1] Theophylline; [18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬
[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299
20 Thiabendazole -[0] ---
21 Thioridazine -[0] ---
22 Thiothixene -[0] ---
23 Timolol [1] Timolol[2] Timolol; TIMOLOL MALEATE; [2] ADRB1,
ADRB2 💬
[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 157, 227
24 Tolazamide -[0] ---
25 Tolbutamide -[0] ---
26 Tolnaftate -[0] ---
27 Torsemide -[0] ---
28 Trandolapril -[0] ---
29 Triacetin [1] Triacetin[1] Glyceryl triacetate; --[1] 307
30 Triamcinolone [1] Triamcinolone[4] Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
31 Triamterene -[0] ---
32 Triazolam -[0] ---
33 Triflupromazine -[0] ---
34 Trifluridine -[0] ---
35 Trimethadione -[0] ---
36 Trimipramine -[0] ---
37 Troglitazone -[0] ---
38 Tromethamine [1] Tromethamine[4] Tham; Tris; Trometamol; Tromethamine; --[5] 51, 96, 97, 226, 299
39 Tropicamide [1] Tropicamide[1] Tropicamide; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 19
40 Terfenadine -[0] ---
41 Topiramate [1] Topiramate[2] TOPAMAX; Topiramate; [36] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬
[53] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193
42 Tetracaine -[0] ---
43 Thiotepa [1] Thiotepa[1] Thiotepa; --[12] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285
44 Timolol maleate [1] Timolol[2] Timolol; TIMOLOL MALEATE; [2] ADRB1,
ADRB2 💬
[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 157, 227
45 Terazosin hydrochloride [1] Terazosin[1] Terazosin; [3] ADRA1A,
ADRA1B,
ADRA1D 💬
[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 6
46 Trimetaphan camsilate [1] Trimethaphan[1] Trimethaphan; [1] CHRNA10 💬[1] Neuroactive ligand-receptor interaction 💬[1] 17
47 Telmisartan [1] Telmisartan[1] Telmisartan; [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 66, 67
48 Tolterodine [1] Tolterodine[1] Tolterodine; [1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 17, 53
49 Trichlormethiazide -[0] ---
50 Tazobactam [1] Tazobactam[1] TAZOBACTAM; --[1] 299
51 Terbutaline sulfate [1] Terbutaline[1] Terbutaline; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 118
52 Thiopental sodium -[0] ---
53 Tridihexethyl chloride -[0] ---
54 Thalidomide [1] Thalidomide[1] Thalidomide; [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
55 Tizanidine hydrochloride [1] Tizanidine[1] Tizanidine; [3] ADRA2A,
ADRA2B,
ADRA2C 💬
[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 13
56 Tolcapone [1] Tolcapone[3] Tasmar; Tolcapon; TOLCAPONE; [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[3] 6, 28, 127
57 Trihexyphenidyl hydrochloride [1] Trihexyphenidyl[1] Trihexyphenidyl; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6
58 Thioridazine hydrochloride -[0] ---
59 Trifluoperazine hydrochloride [1] Trifluoperazine[1] Trifluoperazine; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 283, 284
60 Triflupromazine hydrochloride -[0] ---
61 Trazodone hydrochloride [1] Trazodone[1] Trazodone; [4] HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬
[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 2
62 Tranylcypromine sulfate -[0] ---
63 Thimerosal -[0] ---
64 Terconazole -[0] ---
65 Tioconazole -[0] ---
66 Testosterone cypionate [1] Testosterone[1] Testosterone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
67 Testosterone enanthate [2] Testosterone,
Testosterone enanthate
[3] Testosterone; Testosterone Enanthate; Xyosted; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[11] 1, 2, 3, 13, 13, 60, 76, 78, 113, 113, 265
68 Testosterone propionate [2] Testosterone,
Testosterone propionate
[2] Testosterone; Testosterone propionate; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[10] 1, 2, 3, 13, 60, 76, 78, 113, 113, 265
69 Tamoxifen citrate [1] Tamoxifen[2] Tamoxifen; TAMOXIFEN CITRATE; [2] ESR1,
ESR2 💬
[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 2, 86, 113, 227
70 Toremifene citrate -[0] ---
71 Triamcinolone acetonide [1] Triamcinolone[4] Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
72 Triamcinolone diacetate [1] Triamcinolone[4] Kenalog; Naltrexone; Triamcinolone; TRIAMCINOLONE ACETONIDE; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
73 Triamcinolone hexacetonide [1] Triamcinolone[4] Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
74 Tolazoline hydrochloride -[0] ---
75 Tamsulosin hydrochloride -[0] ---
76 Ticlopidine hydrochloride -[0] ---
77 Tirofiban hydrochloride -[0] ---
78 Tragacanth -[0] ---
79 Trioxsalen -[0] ---
80 Thymol [1] Thymol[1] Thymol; --[1] 13
81 Telithromycin -[0] ---
82 Tigecycline [1] Tigecycline[1] Tigecycline; --[1] 93
83 Talc -[0] ---
84 Tribenoside -[0] ---
85 Trospium chloride -[0] ---
86 Thiethylperazine maleate -[0] ---
87 Tazarotene -[0] ---
88 Tranexamic acid [1] Tranexamic acid[1] Tranexamic acid; [1] PLG 💬[4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬[6] 46, 70, 215, 227, 288, 299
89 Tolterodine tartrate [1] Tolterodine[1] Tolterodine; [1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 17, 53
90 Trilostane -[0] ---
91 Tolfenamic acid [1] Tolfenamic acid[1] Tolfenamic Acid; [2] PTGS1,
PTGS2 💬
[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 5
92 Tiemonium iodide -[0] ---
93 Tolvaptan [1] Tolvaptan[3] Jinarc; Samsca; Tolvaptan; [1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[3] 67, 72, 225
94 Trapidil -[0] ---
95 Tegafur [1] Tegafur[0] [1] TYMS 💬[4] Antifolate resistance, Metabolic pathways, One carbon pool by folate, Pyrimidine metabolism 💬[1] 46
96 Tofisopam -[0] ---
97 Tesaglitazar -[0] ---
98 Troxipide -[0] ---
99 Troleandomycin -[0] ---
100 Tiaprofenic acid -[0] ---
101 Terguride [1] Terguride[1] Terguride; [2] DRD2,
PRL 💬
[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 51, 86
102 Tramadol hydrochloride [1] Tramadol[2] Tramadol; Ultracet; [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271
103 Trepibutone -[0] ---
104 Tolciclate -[0] ---
105 Thiamphenicol -[0] ---
106 Tamibarotene [1] Tamibarotene[1] Tamibarotene; [1] RARA 💬[5] Acute myeloid leukemia, Estrogen signaling pathway, Pathways in cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[2] 26, 96
107 Tinidazole -[0] ---
108 Tiopronin -[0] ---
109 Trifluoperazine maleate [1] Trifluoperazine[1] Trifluoperazine; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 283, 284
110 Tibolone -[0] ---
111 Theophylline sodium acetate [1] Theophylline[1] Theophylline; [18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬
[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299
112 Tenoxicam -[0] ---
113 Triprolidine hydrochloride -[0] ---
114 Teprenone -[0] ---
115 Tripamide -[0] ---
116 Titanium dioxide -[0] ---
117 Transfluthrin -[0] ---
118 Tannic acid -[0] ---
119 Travoprost -[0] ---
120 Trimetoquinol hydrochloride -[0] ---
121 Tenofovir disoproxil fumarate [1] Tenofovir disoproxil[4] Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA; --[2] 93, 265
122 Tadalafil [1] Tadalafil[4] Adcirca; Cialis; Tadalafil; TADALAFILO; [1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[7] 6, 51, 75, 84, 86, 113, 210
123 Tranilast [1] Tranilast[1] Tranilast; --[4] 46, 84, 106, 113
124 Tacrine hydrochloride [1] Tacrine[0] [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 46, 271, 299
125 Tocainide hydrochloride -[0] ---
126 Tripelennamine hydrochloride -[0] ---
127 Tiagabine hydrochloride -[0] ---
128 Trovafloxacin mesylate -[0] ---
129 Tropisetron -[0] ---
130 Teicoplanin [1] Teicoplanin[1] Teicoplanin; --[2] 70, 299
131 Trichomycin -[0] ---
132 Tulobuterol [1] Tulobuterol[1] Tulobuterol; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6
133 Topotecan hydrochloride [1] Topotecan[1] Topotecan; [1] TOP1 💬-[1] 25
134 Tubocurarine chloride -[0] ---
135 Terbinafine hydrochloride [1] Terbinafine[1] Terbinafine; --[3] 96, 97, 271
136 Trimeprazine tartrate -[0] ---
137 Tiludronate disodium -[0] ---
138 Tolrestat -[0] ---
139 Tocopherol [1] Tocopherol[2] Tocoferol; Tocopherol; --[6] 13, 49, 90, 206, 257, 298
140 Thiethylperazine -[0] ---
141 Tolmetin -[0] ---
142 Terbinafine [1] Terbinafine[1] Terbinafine; --[3] 96, 97, 271
143 Ticrynafen -[0] ---
144 Trimipramine maleate -[0] ---
145 Temafloxacin hydrochloride -[0] ---
146 Tylosin -[0] ---
147 Tilmicosin -[0] ---
148 Tobramycin sulfate [1] Tobramycin[9] Bethkis; TOBI; TOBI PODHALER; TOBRAMICINA; TOBRAMYCIN; Tobramycin inhalation solution; TOBRAMYCIN SULFATE; Tobramycine; Tobramycinum; --[1] 299
149 Toloxatone -[0] ---
150 Tianeptine -[0] ---
151 Tocilizumab [1] Tocilizumab[3] ACTEMRA; RoActemra; Tocilizumab; [1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
152 Thiethylperazine malate -[0] ---
153 Trifluperidol -[0] ---
154 Talampanel [1] Talampanel[1] Talampanel; [4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬
[16] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[2] 2, 6
155 Teniposide -[0] ---
156 Talniflumate [1] Talniflumate[1] Talniflumate; --[1] 299
157 Tarazepide -[0] ---
158 Tibezonium iodide -[0] ---
159 Tegaserod maleate -[0] ---
160 Trimethobenzamide hydrochloride [1] Trimethobenzamide[3] Tigan; Trimethobenzamide; Trimethobenzamide Hydrochloride; --[1] 6
161 Teceleukin -[0] ---
162 Trastuzumab -[0] ---
163 Tyloxapol -[0] ---
164 Thiamine disulfide -[0] ---
165 Trafermin -[0] ---
166 Tipifarnib [1] Tipifarnib[1] Tipifarnib; [2] FNTA,
FNTB 💬
[1] Terpenoid backbone biosynthesis 💬[1] 34
167 Tanomastat -[0] ---
168 Telinavir -[0] ---
169 Tipranavir disodium [1] Tipranavir[1] Tipranavir; --[1] 265
170 Tacedinaline -[0] ---
171 Talabostat -[0] ---
172 Talactoferrin alfa -[0] ---
173 Tanaproget -[0] ---
174 Tandutinib -[0] ---
175 Tapentadol -[0] ---
176 Tariquidar -[0] ---
177 Tasosartan -[0] ---
178 Tecadenoson -[0] ---
179 Tecastemizole -[0] ---
180 Technetium Tc 99m sulfur colloid -[0] ---
181 Teclozan -[0] ---
182 Teduglutide [1] Teduglutide[1] Teduglutide; [1] GLP2R 💬[1] Neuroactive ligand-receptor interaction 💬[1] 96
183 Tefibazumab [1] Tefibazumab[1] Tefibazumab; --[1] 299
184 Tegaserod -[0] ---
185 Telbermin -[0] ---
186 Temefos -[0] ---
187 Temocillin -[0] ---
188 Temoporfin -[0] ---
189 Temozolomide [1] Temozolomide[1] Temozolomide; --[1] 34
190 Temsirolimus [1] Temsirolimus[1] Temsirolimus; [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[4] 13, 34, 89, 331
191 Tenecteplase -[0] ---
192 Tenidap -[0] ---
193 Tenofovir [1] Tenofovir[1] Tenofovir; --[6] 2, 13, 25, 93, 265, 325
194 Tepoxalin -[0] ---
195 Terbogrel -[0] ---
196 Teriparatide [1] Teriparatide[4] FORSTEO; Forteo; PTH 1-34; Teriparatide; [1] PTH1R 💬[3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[7] 46, 65, 68, 70, 71, 235, 274
197 Terpin hydrate -[0] ---
198 Testosterone ketolaurate [1] Testosterone[1] Testosterone; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[9] 1, 2, 3, 13, 60, 76, 78, 113, 265
199 Testosterone undecanoate [2] Testosterone,
Testosterone undecanoate
[2] Testosterone; Testosterone undecanoate; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[11] 1, 2, 3, 13, 13, 60, 60, 76, 78, 113, 265
200 Tetrofosmin -[0] ---
201 Tetroxoprim -[0] ---
202 Tetracycline metaphosphate -[0] ---
203 Tezacitabine -[0] ---
204 Theophylline [1] Theophylline[1] Theophylline; [18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬
[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299
205 Theophylline sodium glycinate [1] Theophylline[1] Theophylline; [18] ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬
[23] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299
206 Thiamylal -[0] ---
207 Thioguanine [1] Tioguanine[0] [1] HPRT1 💬[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[2] 13, 37
208 Thiostrepton -[0] ---
209 Thiram -[0] ---
210 Thymalfasin [1] Thymalfasin[1] THYMALFASIN; --[2] 65, 299
211 Thymopentin -[0] ---
212 Thyroglobulin -[0] ---
213 Thyrotropin alfa -[0] ---
214 Tiamulin -[0] ---
215 Tiazofurin -[0] ---
216 Ticlatone -[0] ---
217 Tifacogin -[0] ---
218 Tioxidazole -[0] ---
219 Tirapazamine -[0] ---
220 Tocainide -[0] ---
221 Tocladesine -[0] ---
222 Tocophersolan [1] Tocofersolan[1] VEDROP; --[1] 299
223 Tolbutamide sodium, sterile -[0] ---
224 Tolu balsam -[0] ---
225 Toralizumab [1] Toralizumab[1] Anti-CD40L; [1] CD40LG 💬[14] Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬[1] 63
226 Torapsel -[0] ---
227 Torcetrapib -[0] ---
228 Trabectedin [1] Trabectedin[2] TRABECTEDINA; Yondelis; --[1] 159
229 Tramiprosate -[0] ---
230 Trenbolone acetate -[0] ---
231 Treprostinil [1] Treprostinil[4] Remodulin; Treprostinil; Treprostinilo; Tyvaso; [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 51, 84, 85, 86, 88, 210
232 Trestolone acetate -[0] ---
233 Triamcinolone acetonide sodium phosphate [1] Triamcinolone[4] Kenalog; Naltrexone; Triamcinolone; TRIAMCINOLONE ACETONIDE; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
234 Triciribine phosphate -[0] ---
235 Triclocarban -[0] ---
236 Triclofenol piperazine [1] Piperazine[1] Piperazine; --[2] 58, 272
237 Triclosan -[0] ---
238 Trimegestone -[0] ---
239 Trimethoprim sulfate [1] Trimethoprim[2] Bactrim; Trimethoprim; --[8] 36, 44, 49, 60, 61, 85, 298, 299
240 Trimetrexate -[0] ---
241 Trimetrexate glucuronate -[0] ---
242 Tripelennamine citrate -[0] ---
243 Triptorelin [1] Triptorelin[2] GnRH; Triptorelin; [1] GNRHR 💬[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬[2] 49, 76
244 Trodusquemine -[0] ---
245 Troxacitabine -[0] ---
246 Typhoid vaccine -[0] ---
247 Tyrothricin -[0] ---
248 Tafluprost [1] Tafluprost[1] TAFLUPROST; [1] PTGFR 💬[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬[1] 299
249 Thrombomodulin alfa [1] Thrombomodulin Alfa[1] Thrombomodulin Alfa; [1] F2 💬[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬[1] 85
250 Tanespimycin -[0] ---
251 Tedisamil -[0] ---
252 Tesamorelin [1] Tesamorelin[2] GHRH; Tesamorelin; [1] GHRHR 💬[2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 78, 265
253 Tezampanel -[0] ---
254 Tremelimumab [1] Tremelimumab[1] Ticilimumab; [1] CTLA4 💬[4] Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬[1] 96
255 Tipelukast [1] Tipelukast[1] Tipelukast; [1] CYSLTR1 💬[2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 85
256 Terlipressin [1] Terlipressin[1] TERLIPRESSIN; [3] AVPR1A,
AVPR1B,
AVPR2 💬
[5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬[1] 299
257 Telbivudine [1] Telbivudine[0] --[1] 65
258 Talbutal -[0] ---
259 Tiropramide -[0] ---
260 Tioclomarol -[0] ---
261 Triflusal -[0] ---
262 Taurolidine -[0] ---
263 Theodrenaline -[0] ---
264 Tiracizine -[0] ---
265 Tolonidine -[0] ---
266 Troxerutin -[0] ---
267 Tertatolol -[0] ---
268 Talinolol -[0] ---
269 Tiadenol -[0] ---
270 Thenalidine -[0] ---
271 Tolpropamine -[0] ---
272 Tromantadine -[0] ---
273 Tioxolone -[0] ---
274 Tiratricol [1] Tiratricol[1] Tiratricol; [2] THRA,
THRB 💬
[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[2] 78, 139
275 Tiocarlide -[0] ---
276 Terizidone -[0] ---
277 Trofosfamide -[0] ---
278 Treosulfan [1] Treosulfan[2] OVASTAT; Treosulfan; --[6] 13, 19, 62, 65, 283, 286
279 Triaziquone -[0] ---
280 Thiocolchicoside -[0] ---
281 Tetrazepam -[0] ---
282 Tisopurine -[0] ---
283 Tropatepine -[0] ---
284 Tilbroquinol -[0] ---
285 Tenonitrozole -[0] ---
286 Triclabendazole -[0] ---
287 Tetramethrin -[0] ---
288 Tuaminoheptane -[0] ---
289 Tymazoline -[0] ---
290 Thebacon -[0] ---
291 Talastine -[0] ---
292 Tritoqualine -[0] ---
293 Trimazosin -[0] ---
294 Turofexorate isopropyl -[0] ---
295 Trolamine salicylate -[0] ---
296 Tacalcitol -[0] ---
297 Tacrine [1] Tacrine[0] [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 46, 271, 299
298 Tacrolimus [1] Tacrolimus[2] Prograf; Tacrolimus; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
299 Talampicillin -[0] ---
300 Tamoxifen [1] Tamoxifen[2] TAMOXIFEN; TAMOXIFEN CITRATE; [2] ESR1,
ESR2 💬
[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 2, 86, 113, 227
301 Tamsulosin -[0] ---
302 Tandospirone -[0] ---
303 Tasonermin -[0] ---
304 Temocapril -[0] ---
305 Terazosin [1] Terazosin[1] Terazosin; [3] ADRA1A,
ADRA1B,
ADRA1D 💬
[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 6
306 Terbutaline [1] Terbutaline[1] Terbutaline; [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 118
307 Testosterone decanoate [1] Testosterone decanoate[1] Testosterone decanoate; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 113
308 Testosterone phenylpropionate [1] Testosterone phenylpropionate[1] Testosterone phenylpropionate; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 113
309 Tetrabenazine [1] Tetrabenazine[2] Tetrabenazine; Xenazine; [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8
310 Tetramisole -[0] ---
311 Tetryzoline -[0] ---
312 Thiamine [1] Thiamine[2] Thiamine; Vitamin B1; --[5] 8, 13, 93, 145, 265
313 Thioacetazone -[0] ---
314 Thioproperazine -[0] ---
315 Thiosalicylic acid -[0] ---
316 Thonzylamine -[0] ---
317 Tiagabine -[0] ---
318 Tiapride [1] Tiapride[0] [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8
319 Ticarcillin [1] Ticarcillin[1] Ticarcillin; --[1] 299
320 Ticlopidine -[0] ---
321 Tiletamine -[0] ---
322 Tilidine -[0] ---
323 Tiludronic acid -[0] ---
324 Timolol [1] Timolol[2] Timolol; TIMOLOL MALEATE; [2] ADRB1,
ADRB2 💬
[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 157, 227
325 Timonacic -[0] ---
326 Tinoridine -[0] ---
327 Tioguanine [1] Tioguanine[0] [1] HPRT1 💬[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[2] 13, 37
328 Tipepidine -[0] ---
329 Tipranavir [1] Tipranavir[1] Tipranavir; --[1] 265
330 Tirilazad -[0] ---
331 Tirofiban -[0] ---
332 Tixocortol -[0] ---
333 Tizanidine [1] Tizanidine[1] Tizanidine; [3] ADRA2A,
ADRA2B,
ADRA2C 💬
[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 13
334 Tolazoline -[0] ---
335 Teneligliptin -[0] ---
336 Tolperisone [1] Tolperisone[1] Tolperisone; --[1] 13
337 Topotecan [1] Topotecan[1] Topotecan; [1] TOP1 💬-[1] 25
338 Toremifene -[0] ---
339 Tositumomab -[0] ---
340 Tramadol [1] Tramadol[2] Tramadol; Ultracet; [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[5] 46, 70, 78, 226, 271
341 Tramazoline -[0] ---
342 Tranylcypromine -[0] ---
343 Trazodone [1] Trazodone[1] Trazodone; [4] HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬
[6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 2
344 Trenbolone -[0] ---
345 Tretoquinol -[0] ---
346 Trichloroacetic acid -[0] ---
347 Triclofos -[0] ---
348 Trifluoperazine [1] Trifluoperazine[1] Trifluoperazine; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 283, 284
349 Trihexyphenidyl [1] Trihexyphenidyl[1] Trihexyphenidyl; [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6
350 Trimebutine [1] Trimebutine[1] Trimebutine; [2] OPRK1,
OPRM1 💬
[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 51
351 Trimetazidine [1] Trimetazidine[1] Trimetazidine; --[3] 2, 58, 86
352 Trimethobenzamide [1] Trimethobenzamide[3] Tigan; Trimethobenzamide; Trimethobenzamide Hydrochloride; --[1] 6
353 Tripelennamine -[0] ---
354 Triphosadenine -[0] ---
355 Triprolidine -[0] ---
356 Troclosene -[0] ---
357 Trovafloxacin -[0] ---
358 Tagatose -[0] ---
359 Taranabant -[0] ---
360 Tarenflurbil [1] Tarenflurbil[2] FLURBIPROFEN; Tarenflurbil; [4] APH1A,
NCSTN,
PSEN1,
PSENEN 💬
[6] Alzheimer disease, Human papillomavirus infection, Neurotrophin signaling pathway, Notch signaling pathway, Pathways of neurodegeneration - multiple diseases, Wnt signaling pathway 💬[1] 13
361 Telaprevir -[0] ---
362 Teplizumab -[0] ---
363 Terameprocol -[0] ---
364 Thrombin alfa -[0] ---
365 Ticagrelor [1] Ticagrelor[1] Ticagrelor; [1] P2RY12 💬[1] Platelet activation 💬[3] 36, 46, 85
366 Tofimilast -[0] ---
367 Tucotuzumab celmoleukin -[0] ---
368 Thiopropazate -[0] ---
369 Talarozole -[0] ---
370 Talmapimod -[0] ---
371 Tanezumab [1] Tanezumab[1] Tanezumab; [1] NGF 💬[9] Apoptosis, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[2] 226, 298
372 Tasimelteon [1] Tasimelteon[1] Tasimelteon; [2] MTNR1A,
MTNR1B 💬
[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[1] 202
373 Tecovirimat -[0] ---
374 Telcagepant -[0] ---
375 Tafamidis [1] Tafamidis[2] Tafamidis; Vyndaqel; [1] TTR 💬[1] Thyroid hormone synthesis 💬[1] 28
376 Taliglucerase alfa [1] Taliglucerase alfa[3] Elelyso; PrGCD; TALIGLUCERASE ALFA; [1] GBA 💬[4] Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬[1] 19
377 Tecarfarin -[0] ---
378 Teprotumumab [1] Teprotumumab[1] TEPEZZA; [1] IGF1R 💬[29] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, HIF-1 signaling pathway, Hepatocellular carcinoma, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬[1] 51
379 Tipapkinogene sovacivec -[0] ---
380 Tivozanib -[0] ---
381 Tonapofylline -[0] ---
382 Tedizolid [1] Tedizolid[1] Tedizolid; --[1] 299
383 Tedizolid phosphate -[0] ---
384 Taspoglutide -[0] ---
385 Topiroxostat -[0] ---
386 Talimogene laherparepvec -[0] ---
387 Taprenepag -[0] ---
388 Tofacitinib [1] Tofacitinib[4] Tasocitinib; Tofacitinib; XELJANZ; Xeljanz XR; [4] JAK1,
JAK2,
JAK3,
TYK2 💬
[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
389 Tegobuvir -[0] ---
390 Telapristone acetate -[0] ---
391 Telotristat [1] Telotristat[1] Telotristat; [2] TPH1,
TPH2 💬
[4] Folate biosynthesis, Metabolic pathways, Serotonergic synapse, Tryptophan metabolism 💬[1] 97
392 Telotristat ethyl -[0] ---
393 Temanogrel -[0] ---
394 Tofogliflozin -[0] ---
395 Tralokinumab [1] Tralokinumab[1] Tralokinumab; [1] IL13 💬[8] Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬[2] 85, 97
396 Trastuzumab emtansine -[0] ---
397 Tosedostat -[0] ---
398 Tylvalosin -[0] ---
399 Tabalumab [1] Tabalumab[1] TABALUMAB; [1] TNFSF13B 💬[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[2] 46, 49
400 Tanzisertib -[0] ---
401 Tavaborole -[0] ---
402 Tedatioxetine -[0] ---
403 Teriflunomide [1] Teriflunomide[2] AUBAGIO; TERIFLUNOMIDE; [1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[3] 13, 25, 26
404 Tivantinib -[0] ---
405 Tozadenant [1] Tozadenant[1] TOZADENANT; [1] ADORA2A 💬[7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬[1] 6
406 Trametinib [1] Trametinib[2] Mekinist; Trametinib; [2] MAP2K1,
MAP2K2 💬
[89] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[4] 2, 34, 279, 280
407 Trebananib -[0] ---
408 Trelagliptin -[0] ---
409 Trabedersen -[0] ---
410 Turoctocog alfa -[0] ---
411 Tirasemtiv [1] Tirasemtiv[1] Tirasemtiv; --[1] 2
412 Tildrakizumab [1] Tildrakizumab[2] Ilumetri; Tildrakizumab; [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[2] 162, 271
413 Trenonacog alfa -[0] ---
414 Tovetumab -[0] ---
415 Tenofovir alafenamide [1] Tenofovir alafenamide[1] Tenofovir alafenamide; --[2] 2, 13
416 Tafenoquine -[0] ---
417 Tildipirosin -[0] ---
418 Trabodenoson -[0] ---
419 Taladegib [1] Taladegib[1] Taladegib; [1] SMO 💬[5] Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer 💬[1] 85
420 Talazoparib -[0] ---
421 Temsavir -[0] ---
422 Toreforant -[0] ---
423 Turoctocog alfa pegol -[0] ---
424 Tucidinostat -[0] ---
425 Tezacaftor [1] Tezacaftor[5] Kaftrio; Symdeko; Symkevi; TEZACAFTOR; Trikafta; [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
426 Tibulizumab [1] Tibulizumab[1] Tibulizumab; [2] IL17A,
TNFSF13B 💬
[8] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis, Th17 cell differentiation 💬[1] 53
427 Trilaciclib -[0] ---
428 Tucatinib -[0] ---
429 Tinostamustine -[0] ---
430 Trifarotene -[0] ---
431 Tavilermide -[0] ---
432 Trevogrumab -[0] ---
433 Taldefgrobep alfa -[0] ---
434 Tozuleristide -[0] ---
435 Telisotuzumab -[0] ---
436 Telisotuzumab vedotin -[0] ---
437 Tagraxofusp -[0] ---
438 Tirzepatide -[0] ---
439 Tapinarof -[0] ---
440 Trastuzumab duocarmazine -[0] ---
441 Tisagenlecleucel-T -[0] ---
442 Troriluzole -[0] ---
443 Tavapadon [1] Tavapadon[2] PF-06649751; TAVAPADON; [2] DRD1,
DRD5 💬
[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
444 Tazemetostat -[0] ---
445 Tomivosertib -[0] ---
446 Triheptanoin [1] Triheptanoin[1] TRIHEPTANOIN; --[10] 2, 8, 65, 149, 156, 248, 256, 257, 317, 324
447 Tiragolumab -[0] ---
448 Tislelizumab -[0] ---
449 Tomaralimab -[0] ---
450 Tilsotolimod -[0] ---
451 Trastuzumab deruxtecan -[0] ---
452 Tropifexor [1] Tropifexor[1] Tropifexor; [1] NR1H4 💬[1] Bile secretion 💬[1] 93
453 Tafasitamab -[0] ---
454 Tenapanor -[0] ---
455 Tirbanibulin -[0] ---
456 Tepotinib -[0] ---
457 Taniborbactam -[0] ---
458 Tradipitant -[0] ---
459 Telaglenastat -[0] ---
460 Tezepelumab -[0] ---
461 Tesevatinib [1] Tesevatinib[1] Tesevatinib; [5] EGFR,
EPHB4,
ERBB2,
FLT4,
KDR 💬
[53] Adherens junction, Axon guidance, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction, VEGF signaling pathway 💬[1] 67
462 Taselisib -[0] ---
463 Tarextumab -[0] ---
464 Tofersen [1] Tofersen[1] Tofersen; [1] SOD1 💬[8] Amyotrophic lateral sclerosis, Chemical carcinogenesis - reactive oxygen species, Huntington disease, Longevity regulating pathway - multiple species, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Peroxisome, Prion disease 💬[1] 2
465 Tisotumab vedotin -[0] ---
466 Taurursodiol [1] Tauroursodeoxycholic acid[2] Tauroursodeoxycholic acid; TUDCA; --[4] 2, 13, 93, 299
467 Tozinameran [1] Pfizer-BioNTech COVID-19 Vaccine[2] Comirnaty; Tozinameran; --[5] 13, 46, 51, 53, 299
468 Tixagevimab -[0] ---
469 Thyme -[0] ---
470 Thyme oil -[0] ---
471 Teclistamab -[0] ---
472 Tesnatilimab -[0] ---
473 Talquetamab -[0] ---
474 Toripalimab -[0] ---
475 Tegoprazan -[0] ---