Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	ABAT	[4] Valine, leucine and isoleucine degradation, Propanoate metabolism, Metabolic pathways, GABAergic ...	D00399	Valproic acid	[17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
2	ABAT	[4] Valine, leucine and isoleucine degradation, Propanoate metabolism, Metabolic pathways, GABAergic ...	D00535	Vigabatrin	[2] 145, 158
3	GABBR1	[5] Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, GnRH secretion, ...	D00241	Baclofen	[7] 2, 10, 13, 18, 65, 149, 206
4	GABBR1	[5] Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, GnRH secretion, ...	D08861	Arbaclofen Placarbil	[1] 13
5	GABBR1	[5] Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, GnRH secretion, ...	D09791	Arbaclofen	[2] 13, 206
6	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00225	Alprazolam	[2] 8, 75
7	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00267	Chlordiazepoxide	[1] 46
8	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00280	Clonazepam	[1] 6
9	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00293	Diazepam	[3] 46, 155, 298
10	GABRA1	[6] Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00365	Lorazepam	[2] 36, 231

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